Contact details
Contact
Email:
jianhanc [at] umass [dot] edu
About
We use computer modeling as a primary tool to understand how biomolecules perform their biological functions, via stable 3D structures, or, equally important, lack of stable structures.
Current focus areas:
- Intrinsically disordered proteins: structure, function and disease
- Multi-scale simulations of biomolecular condensates
- Coarse-grained modeling of flexible RNAs
- Gating and regulation of ion channel proteins
- Advanced sampling techniques and implicit solvent models
- Statistical learning and prediction of protein function