Alex Knee

Alex Knee

AL-iks Nee
Lecturer in Biostatistics

Applied biostatistics/epidemiology, scientific review, clinical research

Location

Arnold House

715 North Pleasant Street
Amherst, MA 01003
United States

410 Arnold House

Links

Alex Knee is an applied epidemiologist/biostatistician with nearly 20 years of experience collaborating on clinical research and leading scientific review for a large academic medical center. He has broad expertise consulting on observational and experimental study design and grant development across a range of clinical settings such as: Behavioral Health, Cardiology, Infectious Disease, Internal Medicine, Nursing, Obstetrics & Gynecology, Oncology, Pathology, Pediatrics, Pharmacy and Surgery. In addition to his applied experience, he is a long-time educator, and much of his applied experience is incorporated within his teaching through applications with reproducible reporting, harnessing clinical data systems, data management, interpreting statistical analyses and scientific publication.  His main interests are related to the promotion of evidence based scientific methods in applied settings and the reduction of research waste.

Education

  • MS, University of Massachusetts Amherst
  • BS, University of New Hampshire

Key Publications

Hsu A, Arny M, Knee AB, Bell C, Cook E, Novak AL, Grow D. Antral Follicle Count (AFC) in Clinical Practice: Analyzing Clinical Relevance. Fertil Steril: February 2011: 95(2), 474-479.

Goff SL, Pekow PS, Markenson G, Knee A, Chasan-Taber L, Lindenauer PK. Validity of using ICD-9-CM codes to identify selected categories of obstetric complications, procedures and co-morbidities. Paediatr Perinat Epidemiol. 2012 Sep;26(5):421-9. doi: 10.1111/j.1365-3016.2012.01303.x. Epub 2012 Jul 23. PMID: 22882786.

Soares WE 3rd, Knee A, Gemme SR, Hambrecht R, Dybas S, Poronsky KE, Mader SC, Mader TJ. A Prospective Evaluation of Clinical HEART Score Agreement, Accuracy, and Adherence in Emergency Department Chest Pain Patients. Ann Emerg Med. 2021 Aug;78(2):231-241. doi: 10.1016/j.annemergmed.2021.03.024. Epub 2021 Jun 18. PMID: 34148661; PMCID: PMC8324528.

Goldsweig AM, Knee A, Tak HJ, Desai NR, Bradley SM, Lotfi AS, Spertus JA, Goldsweig BK. Cardiovascular Event Prevalence in Type 1 Versus Type 2 Diabetes: Veradigm Metabolic Registry Insights. J Soc Cardiovasc Angiogr Interv. 2025 Feb 12;4(3Part A):102502. doi: 10.1016/j.jscai.2024.102502. PMID: 40231053; PMCID: PMC11993881.

Stefan MS, Knee AB, Ready A, Rastegar V, Burgher Seaman J, Gunn B, Shaw E, Bannuru RR. Efficacy of models of palliative care delivered beyond the traditional physician-led, subspecialty consultation service model: a systematic review and meta-analysis. BMJ Support Palliat Care. 2022 Apr 19:bmjspcare-2021-003507. doi: 10.1136/bmjspcare-2021-003507. Epub ahead of print. PMID: 35440488.