Image
Bridget Twombly '24
Royal College of Surgeons Graduate Award
About
2024
Biomedical Engineering
RCSI StAR PhD Programme
Fall 2024-Spring 2028
Ireland
My project is looking for tissue engineering solutions to post traumatic osteoarthritis (PTOA) by first using in vitro models to study how damage to subchondral bone cells (caused during knee injury) can evoke inflammatory responses. This inflammatory response communicates via a bone-cartilage crosstalk mechanism to drive cartilage degeneration. I will also evaluate a drug candidate that blocks a step in this process as an early intervention treatment to prevent PTOA.