Lynne A. McLandsborough

Food safety, cleaning and sanitation, biofilm formation and removal; antimicrobial delivery systems

Food processors are moving away from water-based (wet) cleaning in the food processing environment because water enhances bacterial growth. In addition, some food products, such as peanut butter or chocolate, are often manufactured without wet cleaning and rely solely on non-water-based (dry cleaning) approaches to cleaning. Furthermore, under dry conditions (such as those found in peanut butter, chocolate, or dried foods), bacteria, such as Salmonella,exhibit increased resistance to heat and antimicrobial agents. My laboratory group recently focused on developing and formulating antimicrobial compounds for cleaning and sanitizing food processing equipment without water.

Projects in my lab include:

• Development of antimicrobial delivery systems for cleaning and sanitation
• The biological, physical, and chemical aspects of bacterial adhesion, transfer, and removal.
• The genetics of Listeria sp. biofilm growth.

Winner, 2024 Mahoney Life Sciences Prize

Finalist, 2018-2019 UMass Distinguished Teaching Award

College of Food and Natural Resources Certificate for Excellence in Teaching, December 2000 

College of Food and Natural Resources Outstanding Teacher Award, Dec 2001

College of Food and Natural Resources Outstanding Advisor Award

Recent Publications

• Bechtel, T.D.  J. Hershelman, M. Ghoshal, L. McLandsborough, J. G. Gibbons. 2024. Chemical mutagenesis of Listeria monocytogenes for increased tolerance to benzalkonium chloride shows independent genetic underpinnings and off-target antibiotic resistance PLOS One https://doi.org/10.1371/journal.pone.0305663
• Noptana, R. D. J. McClements, L. A. McLandsborough, and E. Onsaard. 2024.  Comparison of characteristics and antioxidant activities of protein hydrolysates and their fractions.  Heliyon e27891  https://doi.org/10.1016/j.heliyon.2024.e27891
• Ryu, V., M. Ghoshal, P. Chuesiang, S. Ruiz-Ramirez, L. McLandsborough, and M. G. Corradini. 2024.  Mechanisms of microbial photoactivation by curcumin’s micellar delivery.  Front. Food Sci Technol. 4:1361817 https://doi.org/10.3389/frfst.2024.1361817
• Chuang, S. L. McLandsborough. 2024 Clean-in-place (CIP) validation of oil-based cleaning and sanitization for Salmonella-contaminated tubing: Evaluation of Enterococcus faecium as a surrogate. Food Control 161:110392 https://doi.org/10.1016/j.foodcont.2024.110392
• Ghoshal, M., T. D. Bechtel, J.G. Gibbons, L. McLandsborough. 2024. Transcriptomic analysis using RNA sequencing and phenotypic analysis of Salmonella enterica after acid exposure for different time durations using Adaptive Laboratory Evolution. Front. Microbiology: 15:1348063 https://doi.org/10.3389/fmicb.2024.1348063
• Ghoshal M, Bechtel TD, Gibbons JG, McLandsborough L. 2023 Adaptive laboratory evolution of Salmonella enterica in acid stress. Front Microbiol. Nov 16;14:1285421. https://doi.org/10.3389/fmicb.2023.1285421
• Ryu, V.; Uknalis, J.; Corradini, M.G.; Chuesiang, P.; McLandsborough, L.; Ngo, H.; Jin, T.; Fan, X. 2023. Mechanism of Synergistic Photoinactivation Utilizing Curcumin and Lauric Arginate Ethyl Ester against Escherichia coli and Listeria innocua. Foods  12: 4195. https://doi.org/10.3390/foods12234195
• Gensler, C., K. Harper, S. Stoufer, M. D. Moore, A. J. Kinchla, & L. McLandsborough 2023. Exploring washing procedures for produce brush washer.  J. Food Prot.  86:100126 https://doi.org/10.1016/j.jfp.2023.100126
• Chuang, S., Ghoshal, M., & McLandsborough, L. 2023. Efficacy of acidified water-in-oil emulsions against desiccated Salmonella as a function of acid carbon chain length and membrane viscosity.  Front. Microbiol. https://doi.org/10.3389/fmicb.2023.1197473
• Chuang, S., Ghoshal, M., & McLandsborough, L. 2023. Oil-Based Sanitization in Low-Moisture Environments: Delivery of Acetic Acid with Water-in-Oil Emulsions. Microbiology Spectrum, e05293-22. https://journals.asm.org/doi/10.1128/spectrum.05293-22
• Ryu,V,  P. Chuesiang, M. G. Corradini, L. McLandsborough, T. Jin, H. Ngo, X.Fan. 2023. Synergistic photoinactivation of Escherichia coli and Listeria innocua by curcumin and lauric arginate ethyl ester micelles. LWT 173: 114317. https://doi.org/10.1016/j.lwt.2022.114317
• Goshal, M, S. Chuang, Y. Zhang, and L. McLandsborough. 2022. Efficacy of acidified oils against Salmonella in low-moisture environments. Appl Environ Microbiol 88: e00935-22 https://doi.org/10.1128/aem.00935-22 *Selected for ASM press release 8/8/2022
• Ghoshal, M., V. Ryu, and L. McLandsborough. 2022. Evaluation of the efficacy of antimicrobials against pathogens on food contact surfaces using a rapid microbial log reduction detection method. Intl J. Food Microbiol 373:109699.