George M. Church, PhD ’84, is professor of genetics at Harvard Medical School, a founding member of the Wyss Institute, and director of PersonalGenomes.org, the world’s only open-access information on human genomic, environmental, and trait data. Church is known for pioneering the fields of personal genomics and synthetic biology. He developed the first methods for the first genome sequence & dramatic cost reductions since then (down from $3 billion to $600), contributing to nearly all “next generation sequencing” methods and companies. His team invented CRISPR for human stem cell genome editing and other synthetic biology technologies and applications – including new ways to create organs for transplantation, gene therapies for aging reversal, and gene drives to eliminate Lyme Disease and Malaria. Church is director of IARPA & NIH BRAIN Projects and National Institutes of Health Center for Excellence in Genomic Science. He has coauthored 450 papers, 105 patents, and one book, “Regenesis”. His honors include Franklin Bower Laureate for Achievement in Science, the Time 100, and election to the National Academies of Sciences and Engineering.
His talk "Synthesis & Analysis of Biopolymers" will be held on Thursday, September 19th at 11:30 in LGRT 1634.
Abstract: We have improved technologies for reading and writing nucleic acid and proteins 10 million fold since 2001. We can design and test millions to trillions of engineered genomes, gene therapy capsids, and combinatorial protein mixtures. But this progress is not limited to linear polymers nor to biology, but enables analysis, synthesis, and high throughput functional testing of a variety of complex, yet atomically precise 3D structures including novel chiralities, high density data storage, nanopores etc.