Shape Instabilities and Curvature Localization in Photo-isomerizing Lipid GUVs Controlled by Excitation Rate and Tension
Speaker: Chris Oville
Authors: Chris Oville, Haim Diamant, and Tony Dinsmore
We drive compression and shape instabilities in lipid membranes composed of photo-isomerizing, azobenzene-based lipids and develop quantitative design principles. Under blue or UV exposure, giant unilamellar vesicles (GUVs) undergo rapid, reversible changes in area and stress. By modulating the rate of increase of UV intensity, we tune the rate of isomerization from straight to bent lipid tails and thereby reduce tension – and even drive compression. Slow UV-ramp rates produce nearly isotropic expansion with fluctuation amplitudes up to 1,000x thermal. Ramping rates above 1/(15s) produce transient "extended modes" - lobed excitations with dominant mode numbers ranging from n = 3 to n = 7, extracted from the vesicle's equatorial contour. An increase in n with UV ramping rate is evident in multiple same-vesicle experiments as well as across vesicles. From real-space fluctuations, we measure the tension during photo-excitation and find periods of compression lasting upwards of 60s. We find quantitative agreement of the peak mode numbers and growth rates with a continuum theory of extended mode growth as a function of relative perimeter change, radius, bending modulus, initial tension, and a novel measurement of an effective dilational viscosity. In some GUVs, a single proboscis-like protrusion or "localized mode" is observed. We examine the energetics of this state theoretically. In cell membranes, active proteins give rise to control of membrane tension, shape, topology, and permeability. Here, we show that we can achieve similar responses in a robust, photo-isomerizing, synthetic lipid system.
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Extreme Clusters and Particle Memory in Decaying Hydrodynamic Turbulence
Speaker: Zhiyu Yang
Authors: Zhiyu Yang, Enrico Calzavarini, Rodolfo Monico, and Varghese Mathai
Particles of different densities are known to show variations in acceleration statistics and preferential concentrations in statistically stationary turbulence. Yet, there is a limited understanding of whether a universal clustering response is possible in decaying isotropic turbulence. We show using experiments and simulations that decay can drive an increase in the clustering, exceeding even the upper bound of clustering possible in stationary turbulence. Standard deviation of cluster volumes show non-monotonic trends depending on the particle inertia and density, although the mean cluster size does grow in decaying turbulence. We show that the fractal dimension of clusters for particles of wide-ranging densities may be collapsed using a revised effective evolving Stokes built on an intermediate sized eddy.
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Low-temperature Depletion of Superfluid Density in the Absence of Galilean Symmetry
Speaker: Viktor Berger
Authors: Viktor Berger, Nikolay Prokof'ev, and Boris Svistunov
Landau theory of superfluidity associates low-temperature flow of the normal component with the phonon wind. This picture does not apply to superfluids in which Galilean invariance is broken either by disorder, porous media, or lattice potential, and the phonon wind is no longer solely responsible for depletion of the superfluid component. Based on Popov's hydrodynamic action with anharmonic terms, we present a general theory for low-temperature (T) dependence of the superfluid stiffness, which reproduces Landau result as a special case when several parameters of the hydrodynamic action are fixed by Galilean invariance, and validate it with numerical simulations of interacting lattice bosons. In a broader context, our approach reveals universal low-temperature thermodynamics of superfluids with an intrinsic connection between finite-T and finite-size (L) effects implying universal scaling, Td+1 and 1/Ld+1, respectively, for a large class of thermodynamic quantities. We discuss the experimental detection of this law and compare our prediction to the existing literature.