Jan Pinkas

Former PI: 

Jan Pinkas earned his Doctor of Philosophy degree in Molecular and Cellular Biology in 1998. His dissertation was titled "Alternative Splicing Of Mdm2 During Breast Tumorigenesis and Mammary Gland Development." Dr. Pinkas was a postdoctoral fellow in Dr. Philip Leder's laboratory in the Genetics Department at Harvard Medical School. He has been employed as a research scientist at Genzyme and Amgen and is currently the Senior Director of Translational Research at ImmunoGen, Inc. There he leads a research team charged with utilizing animal model systems to understand features of ImmunoGen’s antibody-maytansinoid conjugates that impact tolerability, pharmacokinetics, metabolism and anti-tumor activity. In addition, he is responsible for preclinical development-related pharmacology, toxicology, pharmacokinetic, IHC/biomarker activities to support molecules advancing to IND as well as molecules currently in clinical development.