Microbiology | Courses | Faculty
(All courses carry 3 credits unless otherwise noted.)
160 Biology of Cancer and AIDS (BS) (both sem)
Not for credit toward major. How cancer and AIDS begin and progress. The roles
of individual cells, the immune system, mutations and viruses. How various physical
and subtle factors influence one's chances of getting cancer. How to not get
AIDS. The principles of vaccine development and why AIDS presents special difficulties.
Established and new medical treatments for cancer and AIDS. What cancer and
AIDS can teach us about health, healing, disease, living, and dying.
170 Plant Diseases: Feast or Famine (BS) (2nd sem)
Not for majors. Plant diseases and their effects on food supplies and human
history. Biology of pathogens that cause plant diseases, pesticide use, disease
resistance, biological control, and diseases that threaten important world crops.
Not recommended for Plant Science majors.
255 Introduction to Medical Microbiology (BSL) (2nd sem)
Not for majors. With lab. Basic concepts of microbiology with emphasis on microbial
pathogenesis and immunity. Medically important microorganisms including bacteria,
fungi, viruses, rickettsia, protozoa, and the diseases which they produce. Laboratory
exercises develop fundamental skills in aseptic technique, microscopy, pure
culture study, and the isolation and identification of pathogenic microorganisms.
Prerequisites: BIOCHM 205 and BIOL 339. Restricted to undergraduate Nursing
310 General Microbiology (both sem)
Overview of the microbial world including a survey of the structure, functioning,
and diversity of microorganisms. Introduction to the fundamental concepts of
microbial physiology, ecology, genetics, and pathogenesis. Prerequisite: CHEM
261 or concurrent enrollment.
312 Microbiology Laboratory (both sem) 2 cr
Microbiological laboratory procedures including sterile technique, microscopy,
enrichment and isolation, and preservation. Extensive experience in the cultivation
of microorganisms. Prerequisite: MICBIO 310 or concurrent enrollment.
320 Infectious Disease and Defense
The mechanisms by which microorganisms, including bacteria, protozoa, fungi,
and viruses, infect animals and plants and cause disease, and the mechanisms
of host defense against infectious microbes. Emerging and reemerging infectious
diseases of plants and animals and development of resistance to antimicrobial
chemicals. Prerequisites: BIOL 100, 101 and MICBIO 310.
330 Microbial Genetics (2nd sem)
Basic concepts of microbial genetics, and genomics. Both classic and modern
experimental approaches to studies of fundamental genetic processes. Prerequisites:
MICBIO 310 or BIOL 100 and 101 or consent of instructor.
360 Writing in Microbiology (1st sem)
Satisfies the Junior Year Writing requirement. Students develop their writing
skills while completing a series of short assignments. Each participant will
identify a biological topic of their choice to research and write about during
the semester. Prerequisites: ENGL WP 112 and MICBIO 310.
396, 496 Independent Study (both sem) 1-6 cr
Individual study of a selected problem for qualified students. By arrangement.
480 Microbial Physiology (2nd sem)
Experimental approaches used to define essential aspects of bacterial growth,
including energy metabolism, biosynthesis of macromolecule precursors and their
assembly into macromolecules, and the integration of these processes by various
regulatory mechanisms. Emphasis on the isolation and characterization of mutants
blocked in key cell functions. Prerequisite: MICBIO 310.
491A Seminar (1st sem) 1 cr
Senior Seminar required for all majors.
498 Senior Honors (both sem) 4 cr
Senior research, thesis option. By arrangement with department and/or Honors
499 Senior Honors (both sem) 1-5 cr
Continuation of 498. Thesis mandatory. By arrangement with department and/or
515 Management and Ecology of Plant Diseases
The ecology of plant, microbe, and human interactions in plant disease, from
wilderness to industrial farms. Epidemics, traditional farming, environmental
impacts, and sustainability issues. Ways in which agriculture, particularly
plant production and plant disease management, change ecosystems. Individual
project. BIOL 100 or equivalent recommended.
520 Mycology 4 cr
With lab. Biology, ecology, physiology, and taxonomy of fungi. Includes consideration
of fungi as causes of diseases in animals, humans, and plants, and their
uses in biotechnology applications such as bioremediation. Prerequisites: BIOL
530 General Plant Pathology (1st sem) 4 cr
With lab. The causes, nature, and control of plant diseases. Diagnosis of plant
diseases. Mechanisms, biochemistry, and genetics of plant disease; induction,
development, and management. Prerequisite: course in biology.
535 Diagnostic Plant Pathology 4 cr
With lab. Methods of diagnosing plant diseases caused by fungi, bacteria, viruses,
nematodes, and abiotic agents considered, using speciments collected by students.
Individual project. Prerequisite: MICBIO 530 or consent of instructor.
The cellular and molecular bases for innate and adaptive immune responses.
Antigens, antibodies, complement, T and B lymphocytes, helper and killer cells,
macrophages, and their genetics, interactions and significance in immunity to
infectious disease, allergy, autoimmunity, organ graft rejection, cancer immunodeficiencies.
Prerequisites: CHEM 261, BIOCHM 285, and introductory course in biology including
cell structure and physiology.
542 Immunology Laboratory
(2nd sem) 2 cr
Protein chemistry of antibodies, including salt precipitation, ion exchange
and molecular sieving columns, spectrophotometry, polyacrylamide gel electrophoresis
and western blotting, enzyme-linked immunoassay, and estimation of errors. Anatomy
of the lymphatic system. Cellular immunology including histology of leukocytes,
normal and diseased lymphoid tissue, and two-color flow cytometric analysis
of lymphocyte subpopulations. Prerequisite or corequisite: a course in immunology
such as MICBIO 397I or 540.
550 Infection and Immunity (1st sem)
Principles of host-parasite interactions; infections caused by pathogenic bacteria;
virulence factors, such as toxins and microbial structures; pathogenesis and
pathology of bacterial infections; non-specific factors in host resistance and
susceptibility to infectious disease; and immunology of microbial infection.
Prerequisite: MICBIO 310.
552 Pathogenic Bacteriology (1st sem) 2 cr
Lab procedures in clinical and diagnostic bacteriology including: cultural
and physiological characteristics of pathogenic bacteria; cultivation of common
and rare pathogens isolated from clinical material; conventional and rapid biochemical
methods for detection/identification of medically important bacteria; relevant
serological procedures; prescribed tests for susceptibility of bacteria to antibiotics
and antimetabolites. Occasional work outside of scheduled class time required.
Prerequisite: MICBIO 312.
560 Microbial Diversity
Exploration and interpretation of the diversity of microbial life. The role
in nature of various groups of bacteria: their physiology and ecology. Metabolism
and energy conservation in chemoheterotrophic and chemolithotrophic bacteria.
Anoxy-genic and oxygenic photosynthesis in prokaryotes. Bacterial motility and
chemotaxis. Emphasis on anaerobic bacteria. Prerequisite: MICBIO 310 or consent
of instructor. A course in biochemistry is desirable.
565 Laboratory in Molecular Genetics (1st sem) 4 cr
Techniques in modern molecular genetics of bacteria, animals, plants, and yeast.
Includes: isolation of DNA/RNA; DNA cloning and sequencing; polymerase chain
reaction; Southern, Northern and Western blots; signal transduction using reporter
genes; tissue culture; recent advances in genomics and bioinformatics. Prerequisites:
BIOCHM/BIOL 285 and consent of instructor.
Molecular biology of animal viruses and viral genetic systems; viral disease
processes. Concentrates on polio virus, influenza, herpes viruses, HIV, and
the DNA and RNA tumor viruses. Examines some aspects of animal cell molecular
biology. Prerequisite: MICBIO 310 or equivalent life science course (biochemistry
or genetics strongly recommended).
572 Nematology 4 cr
With lab. Biology and identification of soil nematodes. Parasitism of plants
and control measures stressed. Individual project. Prerequisite: MICBIO 530
or consent of instructor.
585 Concepts in Molecular Genetics
Discussion of experiments important in development of fundamental concepts
of molecular genetics. The tranforming principle and the dogma central to recent
progress in DNA replication, recombination, and transposition, and mechanisms
of genetic regulation. Prerequisite: MICBIO 330 or BIOL/BIOCHM 285.
597 Special Topics
Basic concepts of ecological theory applied to microbial interactions. Topics
include: the dynamic relationships between microorganisms and animals, plants,
other microorganisms, and their environments. A general introduction to biogeochemical
cycling in aquatic and terrestrial habitats. Prerequisite: MICBIO 310.
Antibiotics 1 cr
Mechanisms of bacterial resistance to antibiotics. The use of antibiotics as
research tools to probe various aspects of macromolecule synthesis. Topics include
roles of transposons and plasmids in evolution of multiple drug resistance and
resistance to heavy metals. Prerequisite: general background in microbiology,
genetics, and biochemistry.
Agricultural and industrial uses of microorganisms and efforts to genetically
modify microorganisms for specific purposes. Topics include: history and development,
microbial products, microbial biomass as a protein source, bioremediation, N2
fixation, Agrobacterium and the manipulation of plant genes, detection
and monitoring of genetically engineered microorganisms, government regulation
and social implications. Prerequisite: MICBIO 310 or consent of instructor.
Course in genetics desirable.
Microbiology | Courses | Faculty