Directions Centrally located on Main Street in downtown Springfield. Close to major highways and on multiple PVTA bus routes, it’s a convenient ride from just about anywhere. UMass Amherst Center at Springfield 1500 Main St. Springfield, MA 01103 Get Google Maps Directions to UMass Amherst Center at Springfield here. Get Google Maps Directions from UMass Amherst Center at Springfield here. You can print directions from the menu or send directions to your smart phone.