Biomarker Discovery

Xu, H., Gu, X., Tadesse, M. G., Balasubramanian, R. (2018). A modified Random Survival Forests algorithm for variable selection in the presence of imperfect self-reports or laboratory based diagnostic tests, Journal of Computational and Graphical Statistics, in press.

Xu, H.*, Qian, J.*, Paynter, N. P., Zhang, X., Whitcomb, B. W., Tworoger, S. S., Rexrode, K. M., Hankinson, S. E., Balasubramanian, R. (2018): Estimating the area under the Receiver Operating Characteristic (ROC) curve in matched case control studies, Statistics in Medicine, in press. *equal contribution

Paynter, N. P., Balasubramanian, R., Gopal, S., Giulianini, F., Tinker, L., Manson, J.E., Cook, N. R., Albert, C. M., Clish, C., Rexrode, K. M. (2018). Metabolomic Profiles Associated With Coronary Heart Disease in Women, Circulation, 137(8), 841-853.

Qian, J., Payabvash, S., Kemmling, A., Lev, M.H., Schwamm, L.H., and Betensky, R.A. (2014) Variable selection and prediction using a nested, matched case-control study: Application to hospital acquired pneumonia in stroke patients. Biometrics, 70, 153-163.

Qian, J., Nunez, S., Kim, S., Reilly, M.P., and Foulkes, A.S. (2017) A score test for class-level association with non-linear biomarker trajectories. Statistics in Medicine, 36(19):3075-3091.

Qian, J., Hyman, B.T. and Betensky, R.A. (2017) Neurofibrillary tangle stage and the rate of progression of Alzheimer symptoms: Modeling using an autopsy cohort and application to clinical trial design. JAMA Neurology, 74(5):540-548.

Qian, J., Ray, E., Brecha, R., Reilly, M.P. and Foulkes, A.S. A likelihood-based approach to transcriptome association analysis. Statistics in Medicine, in press.