Research Powerhouse: 2016 Report on Research
The image above was captured by a Nikon A1 microscope using enhanced resolution and deconvolution. It shows the endoplasmic reticulum (ER) localization of a novel adapter protein that contributes to cell organization. The image demonstrates colocalization (yellow/orange) in CHO cells between TTC17 (green) and an ER marker (red): the cell's nucleus is displayed in blue. This image is the product of research conducted in UMass Amherst's Institute for Applied Life Sciences examining the processes involved in the maturation and degradation of proteins that cross the secretory pathway in living cells. A number of common human genetic diseases involve protein maturation defects, including cystic fibrosis, albinism, melanoma, and heart disease. Learn more about campus research, including IALS, in the 2016 Report on Research.