4. Why aren't alternatives, like cell culture or computer models, used instead of animals?

Alternatives to the use of whole living animals are being developed constantly, and significant progress has been made in this area over the past 20 years. Animal cell culture lines and computer programs have been substituted in some areas of research, which has contributed to the decrease in the use of live animals.

However, whole animals continue to be necessary in many areas of research where the complicated, multi-system interactions and effects must be assessed. No computer on earth can mimic an entire living system and all the diseases and conditions that can impact that system.

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