Guidance

Animal Care/Use

Name	Description
Adjuvants Use in Research	NIH ARAC guidelines for researchers using adjuvants. Document Link
Agricultural Guide	Guide for the Care and Use of Agricultural Animals in Research and Teaching Download File
Amphibian Eggs and Oocytes	NIH ARAC guidelines to assist investigators in research involving the harvest of eggs and oocytes in Xenopus laevis. Document Link
Cell Line PCR Submission	Procedure for Cell Line PCR submission Download File
Diet Control in Behavioral Animal Studies	NIH ARAC guidelines to assist investigators using diet control in behavioral animal studies.
Disinfectants - NIH Recommendations	Provides guidelines for recommended hard surface disinfectants.
Euthanasia of Animals - AVMA Guidelines	Provides additional guidance regarding the euthanasia of animals. Document Link
Euthanasia of Neonates	NIH ARAC guidelines for researchers working with rodent fetuses or neonates.
Euthanasia of Rodents by CO2	Guidelines for researchers using carbon dioxide for the euthanasia of rodents. Download File
Genotyping Mice and Rats	NIH ARAC guidelines to assist investigators in research involving genotyping of mice and rats.
Guide for the Care and Use of Laboratory Animals	Guide authored by the Institute of Laboratory Animal Research, Commission on Life Sciences, National Research Council. Download File
Guillotine Use and Maintenance	This SOP is intended to provide information for researchers at UMass using rodent guillotines. Download File
Non-Pharmaceutical Grade Compounds - Use	Provides guidelines for the use of non-pharmaceutical grade compounds.
Pain and Distress in Laboratory Animals - Responsibilities	NIH ARAC guidelines regarding pain and distress in laboratory animals and the responsibilities of researchers. Document Link
Pain and Stress Classification Levels	Describes the classification of animal pain and distress levels and provides guidance for action and response based on this classification system.
Survival Bleeding of Mice and Rats	NIH ARAC guidelines to assist investigators in their choice and application of survival rodent bleeding techniques. Document Link
Survival Rodent Surgery	Guidelines to assist investigators in research involving rodent surgery. Download File
Tabletop Isoflurane Anesthesia Machines	Operating Instructions for Tabletop Isoflurane Anesthesia Machines Download File
Use of Fishes in Research	Provides guidelines for the use of fish in research. Document Link
Zebrafish - Use in NIH Intramural Research	Guidelines for use of zebrafish in the NIH Intramural Research Program Document Link