Metal Resistant Plants and Multiple Abiotic Stress-Tolerant Plants

Primary Inventors: 

Transgenic Rice Plants

Dr. Parkash has pioneered his original and novel idea to engineer transgenic rice plants for strong resistance to and decreased uptake of arsenic and heavy metals in order to reduce the movement of toxins in the food chain, as well as producing plants that can thrive in harsh conditions.   Rice is an important staple food of 80% of the world’s human population, and rice straw is used as livestock feed. Arsenic is a potent carcinogen and affects the health of more than 500 million people worldwide.

Stress Tolerant Transgenic plants

Climate changes have made agriculture a difficult proposition for small farmers in rain-fed and marginal lands, while available arable land is decreasing every year. Agricultural crops and vegetables that can thrive in conditions of drought, high salinity, high-temperature or heavy metal contamination will go a long way in addressing the world’s food needs.  


Increased Safety of Food Supplies

Plants grown in heavy metal-contaminated soil accumulate high levels of these pollutants, which then enter the food chain through ingestion of contaminated grain by humans and animals. Decreasing the uptake of toxins by rice plants and other crops will improve the safety of food for direct human consumption, as well as the safety of meat and dairy products.

Scientists at universities and major food corporations have developed transgenic plants with properties that enhance productivity, quality, or nutrition. Dr. Parkash also expects to engineer plants resistant to multiple abiotic stresses such as drought, high salinity, high temperature, and heavy metals. This is accomplished by isolating and characterizing a new family of Stress-Associated Proteins containing zinc-finger domains. By over-expressing genes from this family, transgenic plants gain strong tolerance to various environmental stress as well as metals such as arsenic, cadmium, nickel, manganese, and zinc.





  1. Arsenic free rice and other food crops: Safer rice and other food crops with significantly reduced levels of arsenic for human and animal consumption.
  2. Improved tolerance to Environmental Stress:  The transgenic plants have improved tolerance to drought, heat, and high salinity.
  3. Strong tolerance to Heavy Metals:  The resulting transgenic plants are highly resistant to arsenic, cadmium, nickel, manganese and zinc. This translates to higher yields in metal-contaminated soils when compared to regular plants.
  4. Enhanced biomass:  An interesting property of this technique is that it results in increased plant biomass, making it suitable for use in bioenergy crops like switchgrass, canola and crambe apart from major food crops.
Licensing Status: 
Available for Licensing and Sponsored Research
Patent Status: 

UMA 06-19: Metal Resistant Plants, Methods of Manufacture, and Methods of Use Thereof

PATENT STATUS: US Patent Issued:  US 7,816,579


UMA 07-31: Genes for Improving Tolerance to Heavy Metals and Environmental Stress

PATENT STATUS: US Patent Issued: US 7,951,992

UMA 06-19 and UMA 07-31
For More Information: 

Michael Jaremchuk
Senior Licensing Officer
Commercial Ventures and Intellectual Property
Phone: 413-577-6121