Shuo Sui (he/him)
2014-2020
PhD
Biographical Statement
Shuo obtained his bachelors degree at East China University of Science and Technology over the period of Sep 2009 to July 2013. His degree thesis work was related to the development of a low-volume membrane filtration system to aid in biopharmaceutical manufacturing process development. Shuo’s aspiration is to make real impacts on the modern biopharmaceutical industry, and on human healthcare and well-being. To achieve this ambition, and as a personal trait, Shuo is particularly interested in a career connecting bioscience to manufacturing engineering. Shuo worked on developing high-throughput microfluidic platforms for time-resolved crystallography, which have the potential to enable tremendous advances in the pharmaceutical industry and medicine by enabling direct visualization of the structural dynamics associated with protein function in an automated fashion.
Shuo participated in an internship in spring 2019 with BASF in Ludwigshafen, Germany.
Dr. Shuo Sui successfully defended his PhD dissertation on Microfluidic Platforms for Advanced Crystallography on March 12th, 2020. Dr. Sui was the third PhD student to graduate from the Perry Lab! He since moved first to a postdoctoral research position with Prof. Lois Pollack at Cornell University. He is now a Senior Scientist at Pfizer.
Publications
- S. Sui, A. Mulichak, R. Kulathila, J. McGee,‡ D. Filiatreault, S. Saha, A. Cohen, J. Song, H. Hung, J. Selway, C. Kirby, O.K. Shrestha, W. Weihofen, M. Fodor, M. Xu, R. Chopra, S.L. Perry, "A Capillary-based Microfluidic Device Enables Primary High-throughput Room-temperature Crystallographic Screening," Journal of Applied Crystallography, (2021), 54(4), 1034-1046. [PDF]
- R. Otten, R.A.P. Pádua, H.A. Bunzel, V. Nguyen, W. Pitsawong, M. Patterson, S. Sui, S.L. Perry, A. Cohen, D. Hilvert, D. Kern, "How Directed Evolution Reshapes Energy Landscapes to Boost Catalysis," Science, (2020), 370(6523), 1442-1446. [PDF]
- I.S. Kurtz, S. Sui, X. Hao, M. Huang, S.L. Perry, J.D. Schiffman, "Bacteria-resistant, Transparent, Free-standing Films Prepared from Complex Coacervates," ACS Applied Bio Materials, (2019), 2, 3926-3933. [PDF]
- S. Sui, Y. Wang, C. Dimitrakopoulos, S.L. Perry, "A Graphene-based Microfluidic Platform for Electro-crystallization and In Situ X-ray Diffraction," Crystals, (2018), 8(2), 76. [PDF]
- S. Sui, S.L. Perry, "Microfluidics: From Crystallization to Serial Time-Resolved Crystallography," Structural Dynamics, (2017) 4(3), 032202. [PDF]
- S. Sui, Y. Wang, K.W. Kolewe, V. Srajer, R. Henning, J.D. Schiffman, C. Dimitrakopoulos, S.L. Perry, "Graphene-Based Microfluidics for Serial Crystallography," Lab on a Chip, (2016) 16, 3082-3096. [PDF]
Highlighted in the Lab on a Chip themed collection on Emerging Investigators.
Highlighted in "Serial Crystallography Enhanced by Graphene," Chemistry World[PDF]
Featured as a Science Highlight in the 2016 Annual Report for the Advanced Photon Source.
Featured in an IALS/M2M research highlight.
Patents
- C. Martin, E. Cavac, K.H. Malagodapathiranage, S. Sui, S.L. Perry, Y. Gholamalipour, Novel Enzymatic Methods to Generate High Yields of Sequence Specific RNA Oligonucleotides with Extreme Precision, US Patent No. 11,578,348 B2, Feb. 14, 2023. [PDF]
- S.L. Perry, S. Sui, Graphene-Based Electro-Microfluidic Devices and Methods for Protein Structural Analysis, US Patent No. 11,175,244, Nov. 16, 2021. [PDF]
- S. Sui, Y. Wang, C. Dimitrakopoulos, S.L. Perry, Microfluidic Devices and Methods of Manufacture and Use Thereof, US Patent No. 10,792,657, Oct. 6, 2020. [PDF]
Honors and Awards
2019 |
Poster Award at the BioXFEL Meeting |
2018 |
Poster Award at ICCBM17 |
2018 |
IUCr Travel Award |
Spring 2017 |
Tillwick and Eldridge Teaching Assistant Award |
2017 |
BioXFEL Scholar |
2016 |
IUCr Poster Award at ICCBM16 |
2016 |
International Conference on the Crystallization of Biological Macromolecules Young Scientist Travel Award |