Perry Research Group

Welcome to the Perry Lab

Perry Research Group

Research in the Perry laboratory utilizes self-assembly, molecular design, and microfluidic technologies to generate biomimetic microenvironments to study and enable the implementation of biomolecules to address real-world challenges. Individually, microfluidics represents an enabling technology for high throughput analyses such as the time-resolved structural analysis of enzyme dynamics, while control over molecular interactions in self-assembling polyelectrolyte systems can be used to examine the interplay between biomolecules and the environment. Together, these capabilities can be coupled to generate artificial organelles for use in applications ranging from biochemistry to bioenergetics, biocatalysis, and biomedicine. Furthermore, this work has tremendous pedagogical potential to inspire students to work at the intersection of chemistry, biology, and engineering.

News and Announcements

September 18th, 2022
Timothy Wheeler

Welcome to Timothy Wheeler, a new undergraduate member of the lab who will be studying the effects of temperature on the phase behavior of complex coacervates.

September 18th, 2022
Umme Habeeba

Welcome to Umme Habeeba, a new undergraduate member of the lab who will be studying the encapsulation proteins in peptide-based complex coacervates as a function of different peptide chemistries.

September 15th, 2022
Prof. Sarah Perry

Prof. Perry gave a seminar on X-ray Compatible Microfluidics in the Department of Physics at the University at Buffalo.

September 14th, 2022
Xiangxi (Zoey) Meng

So proud of Zoey Meng for having been awarded the Department of Chemical Engineering Best Dissertation Award for 2021!!!

September 10th, 2022
Drew Knudson

Congratulations to group alum Drew Knudson his new position as a Senior Equipment Engineer at Kite Pharma!

September 8th, 2022
Yaozu Chen

Congratulations to Yaozu Chen on having been selected to participate in the 2022 Gulf Coast Undergraduate Research Symposium!

September 1st, 2022
Diwakaran Rathinam Palaniswamy

Super excited to welcome Diwakaran Rathinam Palaniswamy as a PhD student in the group!

September 1st, 2022
SeungBo Hong

Best wishes and congratulations to SeungBo Hong as he transitions to being an awesome PhD student in the lab of Prof. Scott Auerbach!

August 21st, 2022
ACS Logo

Prof. Perry will be presenting on Polyelectrolyte Complex Materials at a special symposium honoring Matt Tirrell for having won the ACS Award in Colloid Chemistry at the Fall ACS Meeting in Chicago, IL.

August 16th, 2022
2022 IMRC Cancun

Prof. Perry presented on Brushy Nanoparticle Complex Coacervates at a session honoring Matt Tirrell at the International Materials Research Congress in Cancun, Mexico.

August 20th, 2022
Adam Murphy

Congratulations to group alumnus Adam Murphy on starting his new role as a Supervisor in Manufacturing Engineering at Thermo Fisher Scientific!

August 12th, 2022
Louisa Coughlin

Fantastic end to a summer research experience for Louisa Coughlin. We hope you will consider joining us again in the future!

August 5th, 2022
Isaac Ramírez Marrero

So exciting! Isaac Ramírez Marrero was selected to serve as a mentor for the Nextprof Pathfinder Future Faculty Workshop!

August 5th, 2022
Yaozu Chen

Congratulations to Yaozu Chen on having been awarded a Commonwealth Honors College Research Assistant Fellowship!

August 4th, 2022
Mayayi Izzo

Mayayi Izzo presented her research on Encapsulating Protein Using Self-Assembling Peptides at the end-of summer MURALS REU poster session!

August 4th, 2022
Nickolas Holmlund

Nick Holmlund presented the work he has done developing methods to study the Microrheology of Charge-Patterned Peptide-Based Complex Coacervates at the end-of summer undergraduate research poster session!

August 4th, 2022
Yaozu Chen

Yaozu Chen presented his awesome work on Counter-Diffusive Protein Crystallization Using Electrically Actuated Valving as part of the end-of summer undergraduate research poster session!

July 27th, 2022
Prof. Sarah Perry

Prof. Perry presented a poster on Polyelectrolyte Complex Materials at the GRC on Polymer Physics.

July 22nd, 2022
Isaac Ramírez Marrero

Congratulations to Isaac Ramírez Marrero on having been awarded a SACNAS Travel Scholarship to attend the 2022 National Diversity in STEM Conference!

July 15th, 2022
Sarthak Saha

Congratulations to Sarthak Saha on having been awarded the James Douglas Graduate Fellowship to support his proposal to teach Fluid Dynamics this fall and adapt the curriculum to increase student engagement!

July 14th, 2022
2022 World Champion LlabLlama

Congratulations to Prof. Perry on having won the title of World Champion in her Combat Sparring Division at the ATA Martial Arts World Championships!

July 13th, 2022
Prof. Sarah Perry

Prof. Perry presented on Sarthak Saha's work on High Throughput Screening of Crystallization Condition for Protein using X-ray Transparent Microfluidics at the 96th ACS Colloid and Surface Science Symposium, held in Goldon, CO.

July 11th, 2022
2022 EMBL Sarthak Saha

Sarthak Saha presented his research on Counter-Diffusive Protein Crystallization and Liquid Handling in Polymer-based Microfluidic Devices at the EMBL Microfluidic Conference in Heidelberg, Germany!

July 11th, 2022
Prof. Sarah Perry

Prof. Perry presented on Juanfeng Sun's work on Time-Alcohol Superposition of Chitosan/Hyaluronic Acid Complex Coacervates at the 96th ACS Colloid and Surface Science Symposium, held in Goldon, CO.

July 5th, 2022
Sarah Perry

The review article that Prof. Perry and Prof. Charles Sing wrote on the science of complex coacervation in 2020 has been highlighted as one of the top 3% of cited articles from 2021!

"Recent Progress in the Science of Complex Coacervation," C.E. Sing, S.L. Perry, Soft Matter, (2020), 16, 2885-2914. [PDF]

June 28th, 2022
Prof. Sarah Perry

Prof. Perry presented on Coacervate-driven Compartmentalization at the GRC on Systems Chemistry.

June 27th, 2022
Prof. Sarah Perry

Prof. Perry had the privilege of leading the Power Hour discussion on diversity, equity, and inclusion at the GRC on Systems Chemistry!

June 16th, 2022
Li-Wei Chang

Congratulations to Li-Wei Chang, who will soon be starting a new position as a Scientist at Regeneron!

June 14th, 2022
Isaac Ramírez Marrero

Isaac Ramírez Marrero presented his research on Understanding the Mechanical Properties of Polyelectrolyte Complex Materials at the BASF NORA Collaboration Days Event at UMass Amherst!

June 14th, 2022
Dr. Priyanka

Dr. Priyanka presented her work on Exploring Complex Coacervates to Regulate the Release of Agricultural Actives at the BASF NORA Collaboration Days Event at UMass Amherst!

June 13th, 2022
Louisa Coughlin

Welcome to Louisa Coughlin, a high school student who will be studying the effects of polymer chemistry on complex coacervates!

May 31st, 2022
Mayayi Izzo

Welcome to Mayayi Izzo, a summer REU student who is part of the MURALS program. She will be studying protein encapsulation in complex coacervates!

May 25th, 2022
Shannon McIntosh

Congratulations to Shannon McIntosh on accepting a position as a Quality Engineer at Insulet!

May 19th, 2022
Microfluidics Class

Check out this awesome UMass Amherst News Highlight on Prof. Perry's microfluidics class!

May 19th, 2022
Sarthak Saha

Congratulations to Sarthak Saha on having been awarded a fee waiver through the EMBL Corporate Partnership Programme, and travel grant through the BioXFEL program and CBI at UMass to attend the 2022 EMBL Conference on Microfluidics!

May 18th, 2022
Lila Durán Ruiz

Congratulations to Perry lab alumna Lila Durán Ruiz who just earned her M.S. in Chemical Engineering from the University of Waterloo in Canada!

May 16th, 2022
Whitney Blocher McTigue
May 14th, 2022
2022 Kat Nilov Commencement Speaker

Congratulations to Kat Nilov on being selected as the 2022 College of Engineering Commencement Student Speaker! They gave the most amazing, honest, inspiring, and inclusive speech. Looking forward to seeing all of your future successes!

May 13th, 2022
2022 Seniors

Congratulations to our 2022 graduating seniors Luke Boudreau, Shannon McIntosh, and Kat Nilov! We wish each of you the very best!

April 28th, 2022
Whitney Blocher McTigue

We are so excited to host Dr. Whitney Blocher McTigue back on campus to give seminar and be honored for winning the Departmental Best Dissertation Award!

April 9th, 2022
Nickolas Holmlund

Welcome to Nickolas Holmlund, a second year undergraduate who has joined the group to use microrheology to study complex coacervates!

April 6th, 2022
Kat Nilov

Congratulations to Kat Nilov, who has decided to join PhD program in Chemical Engineering at Northeastern University this fall!

April 4th, 2022
University of Florida Logo

Prof. Perry is headed to the Department of Chemical Engineering at the University of Florida to give seminar and talk about science and education with some awesome folks!

March 30th, 2022
Princeton Logo

Prof. Perry had a great visit and seminar to the Department of Chemical and Biological Engineering at Princeton. So much amazing science around the field of coacervates and beyond! It was also a great chance to meet up with group alum Hansen Tjo!

March 23rd, 2021
Maria Santore

Prof. Maria Santore gave a talk on Particle-Integrated Complex Coacervates and the Role of Surface Brushes at the Spring ACS Meeting.

March 15th, 2021
2022 APS March Meeting Logo

Prof. Perry gave an invited talk on Polyelectrolyte Complex Materials as part of the Dillon Medal Symposium honoring Jian Qin at the APS March Meeting.

March 14th, 2021
2022 APS March Meeting Logo

Prof. Perry gave an invited talk on The Effect of Chemistry, Sequence, and Architecture on Complex Coacervation at the APS March Meeting.

March 14th, 2021
2022 APS March Meeting Logo

Prof. Maria Santore gave a talk on Brushing Up on Coacervates: How Chain Anchoring Can Incorporate Solid Particles into Fluid Polyelectrolyte Complexes at the APS March Meeting.

February 28th, 2022
Alex Ayzner

Check out our new collaborative paper with Prof. Alex Ayzner's group from the University of California Santa Cruz on conjugated complex coacervates!

"Conjugated Polyelectrolyte-Based Complex Fluids as Aqueous Exciton Transport Networks," A.R. Johnston, E. Albert-Minckler, M. Shockley, L. Matsushima, S.L. Perry, A.L. Ayzner, Angewandte Chemie International Edition, (2022), 61(20), e202117759. [PDF]

February 25th, 2022
2022 Biotech tAles One Ring

Sarthak Saha and Diwakaran Rathinam Palaniswamy gave an inspired presentation on the benefits of microfluidis for protein crystallography as part of the Biotech tAles debate series.

February 21st, 2022
Emily Ng

Welcome to Emily Ng, a first year undergraduate student who will be studying material properties of polyelectrolyte complexes!

February 10th, 2022
Savannah Szemethy

Congratulations to group alumna Savannah Szemethy on her new position at TScan Therapeutics!

February 9th, 2022
Sarthak Saha

Sarthak Saha gave a great talk and poster on A Microfluidic Device for Room Temperature Crystallography at the 2022 BioXFEL Meeting!

February 7th, 2022
Juanfeng Sun

Check out Juanfeng Sun's latest paper on the effects of cosolvents on the phase behavior and rheology of complex coacervates!

"Linear Viscoelasticity and Time–Alcohol Superposition of Chitosan/Hyaluronic Acid Complex Coacervates," J. Sun, J.D. Schiffman, S.L. Perry, ACS Applied Polymer Materials, (2022), 4(3), 1617-1625. [PDF]

February 4th, 2022
Dr. Mingjun Zhou

Congratulations and best wishes to Dr. Mingjun Zhou, who will be leaving us next week to start a faculty position in Chemistry at Yantai University! Dr. Zhou is the first member of the Perry group to start a faculty career!

February 3rd, 2022
Henry Xu

Welcome to Henry Xu, a first year undergraduate student who will be studying the phase behavior of complex coacervates!

January 28th, 2022
Júlia Bonesso Sabadini

Welcome to Júlia Bonesso Sabadini, a visiting PhD student from the Institute of Chemistry at the University of Campinas (UNICAMP) in Brazil! Júlia is joining us for a year, and will be studying the encapsulation of proteins into coacervate-core micelles.

January 27th, 2022
Isaac Ramírez Marrero

Congratulations to Isaac Ramírez Marrero, who was awarded an Eldridge Teaching Assistant Award for his efforts in ENGIN 110!

January 24th, 2022
Prof. Craig Martin

Check out this news story on the potential of mRNA therapeutics and the work we will be doing with Prof. Craig Martin and Prof. Shelly Peyton!

January 31st, 2022
Alex Lawton

Best wishes to Alex Lawton as he starts his next phase of research in Prof. Lauren Andrews' lab!

January 21st, 2022
Arjun Iyer

Welcome to Arjun Iyer, a first year undergraduate student who will be studying encapsulation of proteins in complex coacervates!

January 13th, 2022
Prof. Craig Martin

Check out this awesome news story on our new collaborative project with Prof. Craig Martin and Prof. Shelly Peyton to revolutionize mRNA therapies!

See more news from 2021.