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  • Specific Aims (1 page)
    Opening paragraph or two.
    The central hypothesis will be tested with XXX specific aims:
    • Aim 1: To determine...
    • Aim 2: To characterize... 
  • Research Strategy (1 page for significance and innovation)
    • Significance. ~0.5 – 0.66 page
    • Innovation. ~0.33 – 0.5 page
  • Approach (Up to 10 pages for Approach)
    • Specific Aim 1: To determine XXX
      • Introduction.
      • Justification & Feasibility.
      • Research Design. (Variable number of sub-aims labeled Study1.X – see below)
      • Study 1.1: To define XXX.
      • Study 1.2: To examine XXX
      • Study 1.3: To measure XXX
      • Study 1.4: To study how XXX
      • Expected Outcomes.
      • Potential Problems & Alternative Strategies.
    • Specific Aim 2: To characterize XXX
      • Introduction.
      • Justification & Feasibility.
      • Research Design.
      • Study 2.1: To XXX
      • Study 2.2: To XXX
      • Study 2.3: To XXX
      • Expected Outcomes.
      • Potential Problems & Alternative Strategies
  • Bibliography