Stylianos Scordilis
Professor of Biological Sciences
Smith College
Scordilis’ research interests are in molecular physiology, myogenesis and sexual dimorphism of skeletal muscle. Ordered, regulated movement is one of the distinguishing characteristics of life. In Scordilis’ lab, students attempt to discover how contractility is maintained following repairable muscle damage. Muscle cells are remarkably adaptable; they can atrophy, hypertrophy, remodel depending on environmental stimuli and repair following a damaging event. All of these adaptations involve stress proteins, enzyme signaling cascades and steroid receptors.
Selected Publications
Morris, E., Abreu, A and S. P. Scordilis. “The Effect of Tamoxifen on Proteome Expression During in vitro Myogenesis in Murine Skeletal Muscle C2C12 Cells.” J Proteome Res., 22: 3040-3053, 2023.
Russ, D., Dimova, K., Morris, E., Pacheco, M., Garvey, S. M. and S. P. Scordilis. Dietary Fish Oil Supplement Induces Age-Specific Contractile and Proteomic Responses in Muscles of Male Rats. Lipids in Health and Disease, 19: 165-177, DOI: 10.1186/s12944-020-01333-4, 2020
Dimova, K., L. Metskas, M. Kulp and S. P. Scordilis. "Skeletal Muscle Gender Dimorphism From Proteomics." J. Vis. Exp. 58, e3536, DOI: 10.3791/3536, 2011.