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Sandra Petersen

Professor

Research in our laboratory focuses on determining: 1) the molecular and cellular mechanisms underlying the brain signal for ovulation; 2) developmental mechanisms responsible for sex differences in the brain; 3) how developmental exposure to environmental contaminants like dioxins and estrogenic substances produces neural dysfunctions in adulthood.

Current Research

  1. The mechanisms through which a non-classical progesterone signaling molecule, progesterone receptor
    component 1, suppresses neuroimmune responses to proinflammatory cytokines in the etiology and
    progression of neurodegenerative diseases.

  2. Mechanisms through which CUG binding protein 2 directs dendritic spine development, a process important for functions ranging from learning and memory to ovulation.
  3. The effects of dioxin-disruption of CUG binding protein 2 during early life on the development of neurodegenerative diseases.

Learn more at www.vasci.umass.edu/research-faculty/sandra-l-petersen

Academic Background

  • BS Biology, Rutgers University, 1977
  • MS Neuroendocrinology, Oregon State University, 1980
  • PhD Neuroendocrinology, Oregon State University, 1984
  • Postdoctoral training, University of Maryland School of Medicine, 1984-1988
Del Pino Sans J 1 , Clements KJ 1 , Suvorov A 1 , Krishnan S 1 , Adams HL 1 , Petersen SL 2 . Neuroscience. 2016 Aug 4;329:239-53. doi: 10.1016/j.neuroscience.2016.04.051. Epub 2016 May 13.
Del Pino Sans J, Krishnan S, Aggison LK, Adams HL, Shrikant MM, López-Giráldez F, Petersen SL.Neuroscience. 2015 Sep 10;303:312-22. doi: 10.1016/j.neuroscience.2015.07.008. Epub 2015 Jul 9. PMID:26166732
THORSON, J.F., L.D. PREZOTTO, H. ADAMS, S.L. PETERSEN, J.A. CLAPPER, E.C. WRIGHT, W.T. OLIVER, B. A. FREKING, A.F. FOOTE, E.D. BERRY, D.J. NONNEMAN AND C.A. LENTS (2018)
 
Contact Info

Department of Veterinary and Animal Sciences
Life Sciences Laboratory N231 Lab N240
240 Thatcher Way
Amherst, MA 01003-9292

(413) 545-1808
spetersen@vasci.umass.edu

www.vasci.umass.edu/research-faculty/sandra-l-petersen