Our research group is interested in creating synthetic DNA- and RNA-based tools for analytical and biomedical applications. Our research program integrates the disciplines of chemistry, bionanotechnology, cellular biology, and synthetic biology. Our ultimate goal is to understand the fundamentals of life, and to construct artificial genetic devices and pathways.
Currently we have four primary research focuses:
- Discover novel molecular mechanisms for precise conditional self-assembly of nucleic acid nanostructures.
- Systematically evolve functional aptamers and ribozymes based on high-throughput approaches.
- Construct RNA circuits and dynamic devices for intracellular imaging of RNAs and metabolites.
- Develop photo-switchable tools for gene expression control, cancer diagnosis and targeted therapy.
Learn more at elements.chem.umass.edu/youlab/
- BS Chemistry, Peking University, 2008
- PhD Chemistry, University of Florida, 2012
- Postdoctoral Scholar, Nano-Optic Joint Program between UF and MSU, 2013
- Postdoctoral Scholar, Pharmacology, Weill Medical College, Cornell University, 2014-2016