The University of Massachusetts Amherst
 
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Lawrence Schwartz

E&R Isenberg Professor of Integrated Science

Research areas include programmed cell death is a fundamental component of development and homeostasis in virtually all organisms. Defects in the regulation of cell death serves as the basis of many human diseases, including auto-immunity, neurodegeneration and most cancers.

Current Research
We are using NextGen sequencing methods to determine the identities and expression patterns for the transcriptome and all of the small RNAs in a model system for skeletal muscle atrophy and death so that we can build a framework for understanding the molecular mechanisms that mediate these processes during development and pathogenesis.

Learn more at www.bio.umass.edu/biology/about/directories/faculty/lawrence-m-schwartz

Academic Background

  • AB. Northwestern University, 1976
  • PhD University of Washington, Seattle, 1982
  • Postdoctoral training: 1982-1984 University of Washington, Seattle; 1984-1987 University of North Carolina, Chapel Hill; 1995-1996 Whitehead Institute for Biomedical Sciences
Hyldahl RD, Schwartz LM, Clarkson PM. (2013) NF-kB Functions in Primary Pericyte Cells in a Cell- and Non-Cell Autonomous Manner to Affect Myogenesis. Muscle and Nerve, 47:522-531.
Fahrbach, S.E., Nambu, J.R. and Schwartz, L.M. (2012) Programmed cell death in insect neuromuscular systems during metamorphosis. in Insect Molecular Biology and Biochemistry, L.I. Gilbert editor, pp 419-449.
Schwartz, L.M., Kosz, L., and Kay, B.K. 1990. Gene Activation is Required for Developmentally Programmed Cell Death. Proc. Natl. Acad. Sci. USA, 87: 6594-6598.
 
Contact Info

Department of Biology
417 Morrill II South
North Pleasant Street
Amherst, MA 01003

(413) 545-2435
schwartz@bio.umass.edu

www.bio.umass.edu/biology/about/directories/faculty/lawrence-m-schwartz