Research areas include programmed cell death is a fundamental component of development and homeostasis in virtually all organisms. Defects in the regulation of cell death serves as the basis of many human diseases, including auto-immunity, neurodegeneration and most cancers.
We are using NextGen sequencing methods to determine the identities and expression patterns for the transcriptome and all of the small RNAs in a model system for skeletal muscle atrophy and death so that we can build a framework for understanding the molecular mechanisms that mediate these processes during development and pathogenesis.
- AB. Northwestern University, 1976
- PhD University of Washington, Seattle, 1982
- Postdoctoral training: 1982-1984 University of Washington, Seattle; 1984-1987 University of North Carolina, Chapel Hill; 1995-1996 Whitehead Institute for Biomedical Sciences