Our lab studies neurocognitive aging in nonhuman primate models, in the context of typical and pathological aging as well as menopause.
The marmoset is a small nonhuman primate that is increasingly used in neuroscience research due to its close resemblance to humans in many aspects of physiology, brain organization and behavior. Due to a short lifespan of about 12 years, the marmoset is uniquely suited for aging studies. Three main projects focusing on marmoset neurocognitive aging are ongoing (1) A longitudinal study seeks to identify the biological correlates of sex differences in cognitive and brain aging, using behavioral, physiological, neuroimaging and neurohistological techniques; (2) In a second project, we are developing a marmoset model for menopausal symptoms in order to understand potential interactions between cognitive deficits, sleep disturbances and thermoregulation impairments that are associated with estrogen loss; (3) Recent studies examine the aged marmoset as a model for preclinical Alzheimer's disease, in order to identify behavioral predictors of neuropathology.
- PhD Université Paul Sabatier, Toulouse, France,1994
- Postdoctoral Training: University of Georgia, 1995; Emory University, 1997
- Postdoctoral Training: Yerkes Natl Primate Res Ctr, Emory University, 1997-2002
- Res Assistant Professor, Yerkes Natl Primate Res Ctr, Emory University 2002-2006
- Assistant Professor, University of Massachusetts, 2006-2012
- Associate Professor, University of Massachusetts, 2012-present