The University of Massachusetts Amherst

Translating fundamental biology

into new targets, leads and disease models

Facility Highlight

Faculty Highlight

Craig Martin , Professor

My group has a longstanding interest in structure and function in enzyme-nucleic acid interactions, with a particular focus on the enzymology of transcription. To understand fundamental mechanisms in the complex process of transcription, we have mostly focused our work on the single subunit model RNA polymerase from bacteriophage T7.

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