
Biomedical Engineering
LSL 625
240 Thatcher Road
Amherst, MA 01003-9292
(413) 545-6366
swdonahue@umass.edu
www.umass.edu/engineering/about/directory/seth-donahue
Professor of Biomedical Engineering
Developing new tissue engineering strategies for bone regeneration by utilizing innovative biomaterials to deliver stem cells and gene therapy to large bone defects. Elucidating the biology, physiology, and mechanics of bone from animals that have adapted to extreme environmental conditions.
Current Research
- Hydrogel delivery of mesenchymal stem cells for bone regeneration.
- Collagen scaffold delivery of microRNA or bone regeneration.
- Bioinspired design for 3D printing.
The Donahue lab studies the biology, physiology, and mechanics of bone from animals that have adapted to extreme environmental conditions. Examples include Trinidadian guppies, little pocket mice, arctic ground squirrels, bighorn sheep, hibernating bears, and dinosaurs. We also use more traditional laboratory rodent models to study treatments for osteoporosis and tissue engineering approaches to regenerating new bone tissue.
Learn more at Donahue Research Group
Academic Background
BS 1992, Worcester Polytechnic Institute - Mechanical Engineering
MS 1997, University of California, Davis - Biomedical Engineering
PhD 1999, University of California, Davis - Biomedical Engineering
Post-Doc 2001, Pennsylvania State University Medical Center - Orthopaedics