The Plant Cell Culture Library

Solanum villosum
Cell Line ID SV-10821
Media Type B105
Lowest Tolerable USDA Zone 9a
Drought Tolerance Averag
Availability High
Order Solanales
Family Solanaceae
Genus Solanum
Antiviral Genus Level ➡ 15 citations
Antibacterial Genus Level ➡ 99 citations
Antifungal Genus Level ➡ 274 citations
Trypanocidal Genus Level ➡ 3 citations
Anthelmintic Genus Level ➡ 6 citations
Insecticidal Species Level
Anticancer Genus Level ➡ 14 citations
Culture Initiation Site Dusseldorf
Plant Habit Herb Annual
Plant Habitat Warm Temperate
Culture Start Material Shoot
Native Range Mediterranean
Plant Supplier Botanical Garden Chelsea Physic Garden
Antiviral Citations
  1. Coxon, D.T. et al., Tet. Lett., 1974, 15, 2921- 2924 (Solavetivone) [https://doi.org/10.1016/S0040-4039(01)91781-2]
  2. Anderson, R.C. et al., Chem. Comm., 1977, 27- 28 (tobacco constit, abs config) [https://doi.org/10.1039/c39770000027]
  3. Yamada, K. et al., Chem. Comm., 1977, 554- 555 (synth, stereochem) [https://doi.org/10.1039/C39770000554]
  4. Stoessl, A. et al., Can. J. Chem., 1978, 56, 645- 653 (biosynth) [https://doi.org/10.1139/v78-106]
  5. Fujimori, T. et al., Phytochemistry, 1979, 18, 2032 (Solavetivone, tobacco constit) [https://doi.org/10.1016/S0031-9422(00)82732-6]
  6. Murai, A. et al., Bull. Chem. Soc. Jpn., 1984, 57, 2276- 2281 (synth) [https://doi.org/10.1246/bcsj.57.2276]
  7. Murai, A. et al., Bull. Chem. Soc. Jpn., 1984, 57, 2282- 2285 (synth) [https://doi.org/10.1246/bcsj.57.2282]
  8. Murai, A. et al., Chem. Lett., 1986, 771- 772 (Oxysolavetivone) [https://doi.org/10.1246/cl.1986.771]
  9. Iwata, C. et al., Chem. Pharm. Bull., 1987, 35, 544- 552 (synth) [https://doi.org/10.1248/cpb.35.544]
  10. Hwu, J.R. et al., JOC, 1992, 57, 922- 928 (synth, abs config, bibl) [https://doi.org/10.1021/jo00029a025]
  11. Takemoto, Y. et al., Tetrahedron, 1997, 53, 603- 616 (synth) [https://doi.org/10.1016/S0040-4020(96)01006-X]
  12. Engstrom, K. et al., Potato Res., 1999, 42, 43- 50 (Solavetivone, activity)
  13. Fu, J.-J. et al., Chem. Pharm. Bull., 2010, 58, 1263- 1266 (Argutosin D)
  14. Arthan, D. et al., Phytochemistry, 2002, 59, 459- 463 (Torvanol A) [https://doi.org/10.1016/S0031-9422(01)00417-4]
  15. Mohan, M. et al., Nat. Prod. Res., 2013, 27, 2140- 2143 (Torvanol A, activity)
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Antibacterial Citations
  1. Aldrich Library of FT-IR Spectra, 1st edn., 1985, 2, 324A, 324C, 326C (ir)
  2. Aldrich Library of 13C and 1H FT-NMR Spectra, 1992, 2, 1314C, 1318A (nmr)
  3. Head, F.S.H. et al., JCS, 1939, 1266- 1267 (Cichoriin, synth)
  4. Jain, B.D., Anal. Chim. Acta, 1967, 37, 135- 138 (detn, Nb, U) [https://doi.org/10.1016/S0003-2670(01)80648-6]
  5. Dean, F.M. et al., Tet. Lett., 1967, 8, 2147- 2151 (Prenyletin) [https://doi.org/10.1016/S0040-4039(00)90785-8]
  6. Khan, M.A.S. et al., Anal. Chim. Acta, 1968, 43, 153- 156 (pmr) [https://doi.org/10.1016/S0003-2670(00)89195-3]
  7. Pousset, J.L. et al., C. R. Seances Acad. Sci., Ser. D, 1970, 271, 2320- 2322 (Baisseoside)
  8. Karrer, W. et al., Konstitution und Vorkommen der Organischen Pflanzenstoffe, 2nd edn., Birkhäuser Verlag, 1972, nos. 1325-1327 (occur)
  9. Sato, M. et al., Phytochemistry, 1972, 11, 657- 662 (biosynth) [https://doi.org/10.1016/0031-9422(72)80029-3]
  10. Günther, H. et al., Org. Magn. Reson., 1975, 7, 339- 344 (di-Me ether, cmr)
  11. Cussans, N.J. et al., Tetrahedron, 1975, 31, 2719- 2726 (cmr) [https://doi.org/10.1016/0040-4020(75)80338-3]
  12. Fischer, F.C. et al., Phytochemistry, 1976, 15, 1078- 1079 (activity) [https://doi.org/10.1016/S0031-9422(00)84415-5]
  13. Forgacs, P. et al., Tet. Lett., 1978, 18, 4783- 4784 (Diospyroside)
  14. Ishikura, N. et al., Bot. Mag., Tokyo, 1982, 95, 303- 308 (6-(3'-Glucosylcaffeoyl)esculetin)
  15. Chiang, M.T. et al., Phytochemistry, 1982, 21, 2753- 2755 (Haplopinol, Prenyletin,Aesculetin activity) [https://doi.org/10.1016/0031-9422(82)83119-1]
  16. Murray, R.D.H. et al., The Natural Coumarins, J. Wiley, 1982 (occur, rev)
  17. Kelkar, S.L. et al., Indian J. Chem., Sect. B, 1984, 23, 458- 459 (Scoparone, synth)
  18. Joseph-Nathan, P. et al., J. Het. Chem., 1984, 21, 1141- 1144 (di-Me ether, pmr)
  19. Abu-Eittah, R.H. et al., Can. J. Chem., 1985, 63, 1173- 1179 (uv) [https://doi.org/10.1139/v85-200]
  20. Jakupovic, J. et al., Phytochemistry, 1988, 27, 3831- 3839 (2-methyl-1-propenyl ether) [https://doi.org/10.1016/0031-9422(88)83027-9]
  21. Nonaka, G. et al., Chem. Pharm. Bull., 1989, 37, 2030 (Aesculin 6'-gallate) [https://doi.org/10.1248/cpb.37.2030]
  22. Niedmann, C. et al., An. R. Acad. Farm., 1990, 56, 171- 179 (Prenyletin, activity)
  23. Dubois, M.A. et al., Phytochemistry, 1990, 29, 3369- 3371 (Palustroside) [https://doi.org/10.1016/0031-9422(90)80221-2]
  24. Qin, B. et al., J. Chin. Pharm. Sci., 1994, 3, 91 (Prionanthoside)
  25. Jackson, Y.A. et al., Heterocycles, 1995, 41, 1979- 1986 (synth) [https://doi.org/10.3987/COM-95-7100]
  26. Sarker, S.D. et al., J. Nat. Prod., 1995, 58, 1109- 1115 (Isobaisseoside) [https://doi.org/10.1021/np50121a023]
  27. Matsuda, N. et al., Phytochemistry, 1995, 38, 803- 804 (6-apiosylglucoside) [https://doi.org/10.1016/0031-9422(94)00668-J]
  28. Dubery, I.A. et al., Phytochemistry, 1999, 50, 983- 989 (Scoparone, activity) [https://doi.org/10.1016/S0031-9422(98)00247-7]
  29. Sultana, N. et al., Phytochemistry, 1999, 52, 895- 900 (3'-Coumaroylisobaisseoside) [https://doi.org/10.1016/S0031-9422(99)00338-6]
  30. Kisiel, W. et al., Fitoterapia, 2002, 73, 544- 546 (6-4-Hydroxyphenylacetylcichoriin) [https://doi.org/10.1016/S0367-326X(02)00172-7]
  31. Torres, R. et al., Phytochemistry, 2006, 67, 984- 987 (7-dimethyloctatrienylcoumarin) [https://doi.org/10.1016/j.phytochem.2006.03.016]
  32. Chen, J.-J. et al., Planta Med., 2006, 72, 935- 938 (Hibiscusin)
  33. Suárez, L.E.C. et al., Rev. Colomb. Quim., 2006, 35, 59- 65 (Solanum validinervium constit)
  34. Zhang, D.-M. et al., J. Integ. Plant Biol., 2007, 49, 218- 221 (6'-Vanilloylaesculin, 6'-Sinapoylaesculin)
  35. Lin, S. et al., J. Nat. Prod., 2007, 70, 817- 823 (6-glucosylhydroxymethoxybenzoylglucoside) [https://doi.org/10.1021/np0700467]
  36. Razavi, S.M. et al., Phytochem. Lett., 2008, 1, 159- 162 (Prenyletin O-apiosylglucoside) [https://doi.org/10.1016/j.phytol.2008.07.009]
  37. Shi, X.-H. et al., J. Asian Nat. Prod. Res., 2009, 11, 49- 53 (6-galloylgalactoside)
  38. Sax's Dangerous Properties of Industrial Materials, 11th edn., J. Wiley, 2004, DRS800 (di-Me ether)
  39. Kim, J.-Y. et al., Int. J. Mol. Sci., 2013, 14, 4349- 4360 (Peptide G2, activity)
  40. Barger, G. et al., JCS, 1936, 1537- 1542 (Solanum pseudocapsicum constit)
  41. Boll, P.M. et al., Antibiot. Annu., 1956, 3, 255- 259 (Solanocapsine, activity)
  42. Budzikiewicz, H., Tetrahedron, 1964, 20, 2267- 2278 (Solanocapsine, ms) [https://doi.org/10.1016/S0040-4020(01)97614-8]
  43. Ripperger, H. et al., Annalen, 1969, 723, 159- 180 (Solanocapsine, pmr, ir, struct)
  44. Höhne, E. et al., Tetrahedron, 1970, 26, 3569- 3577 (Solanocapsine, cryst struct) [https://doi.org/10.1016/S0040-4020(01)92936-9]
  45. Ripperger, H. et al., Tetrahedron, 1972, 28, 1629- 1644 (Solanocapsine, synth) [https://doi.org/10.1016/0040-4020(72)88045-1]
  46. Mitscher, L. et al., Experientia, 1976, 32, 415- 416 (Solacassine, activity) [https://doi.org/10.1007/BF01920766]
  47. Ali, E. et al., Tetrahedron, 1977, 33, 1371- 1377 (Solanoforthine, isol, ms) [https://doi.org/10.1016/0040-4020(77)84088-X]
  48. Bird, G.J. et al., Aust. J. Chem., 1979, 32, 797- 816 (3β-amino steroidal alkaloids, cmr, rev) [https://doi.org/10.1071/CH9790797]
  49. Chakravarty, A.K. et al., JCS Perkin 1, 1984, 467- 474 (O-Methylsolanocapsine, synth) [https://doi.org/10.1039/p19840000467]
  50. Chakravarty, A.K. et al., Phytochemistry, 1988, 27, 956- 958 (7β-Hydroxy-O-methylsolanocapsine, isol) [https://doi.org/10.1016/0031-9422(88)84135-9]
  51. Ripperger, H., Alkaloids: Chem. Biol. Perspect., 1998, 12, 103- 185 (Solanum alkaloids, rev)
  52. Barger, G. et al., JCS, 1936, 1537- 1542 (Solanum pseudocapsicum constit)
  53. Boll, P.M. et al., Antibiot. Annu., 1956, 3, 255- 259 (Solanocapsine, activity)
  54. Budzikiewicz, H., Tetrahedron, 1964, 20, 2267- 2278 (Solanocapsine, ms) [https://doi.org/10.1016/S0040-4020(01)97614-8]
  55. Ripperger, H. et al., Annalen, 1969, 723, 159- 180 (Solanocapsine, pmr, ir, struct)
  56. Höhne, E. et al., Tetrahedron, 1970, 26, 3569- 3577 (Solanocapsine, cryst struct) [https://doi.org/10.1016/S0040-4020(01)92936-9]
  57. Ripperger, H. et al., Tetrahedron, 1972, 28, 1629- 1644 (Solanocapsine, synth) [https://doi.org/10.1016/0040-4020(72)88045-1]
  58. Mitscher, L. et al., Experientia, 1976, 32, 415- 416 (Solacassine, activity) [https://doi.org/10.1007/BF01920766]
  59. Ali, E. et al., Tetrahedron, 1977, 33, 1371- 1377 (Solanoforthine, isol, ms) [https://doi.org/10.1016/0040-4020(77)84088-X]
  60. Bird, G.J. et al., Aust. J. Chem., 1979, 32, 797- 816 (3β-amino steroidal alkaloids, cmr, rev) [https://doi.org/10.1071/CH9790797]
  61. Chakravarty, A.K. et al., JCS Perkin 1, 1984, 467- 474 (O-Methylsolanocapsine, synth) [https://doi.org/10.1039/p19840000467]
  62. Chakravarty, A.K. et al., Phytochemistry, 1988, 27, 956- 958 (7β-Hydroxy-O-methylsolanocapsine, isol) [https://doi.org/10.1016/0031-9422(88)84135-9]
  63. Ripperger, H., Alkaloids: Chem. Biol. Perspect., 1998, 12, 103- 185 (Solanum alkaloids, rev)
  64. Karle, I., Acta Cryst. B, 1970, 26, 1639- 1645 (cryst struct) [https://doi.org/10.1107/S0567740870004661]
  65. Usubillaga, A. et al., JACS, 1970, 92, 700- 701 (Solaphyllidine) [https://doi.org/10.1021/ja00706a047]
  66. Usubillaga, A., Phytochemistry, 1988, 27, 3024- 3027 (cmr) [https://doi.org/10.1016/0031-9422(88)80723-4]
  67. Alarcon, L. et al., Rev. Latinoam. Quim., 2006, 34, 13- 21 (Deacetoxysolaphyllidine, activity)
  68. Pérez Colmenares, A. et al., Nat. Prod. Commun., 2010, 5, 1743- 1746 (Deacetoxysolaphyllidine 3-glucoside, 5,6-Dihydro-4-oxoverazine)
  69. Brink, N.G. et al., JACS, 1951, 73, 4018 (Tomatidine, isol) [https://doi.org/10.1021/ja01152a509]
  70. Kuhn, R. et al., Chem. Ber., 1957, 90, 203- 218 (Tomatines, struct)
  71. Sato, Y. et al., JACS, 1957, 79, 6089- 6090 (Tomatidine, struct) [https://doi.org/10.1021/ja01579a069]
  72. Schreiber, K., Planta Med., 1958, 6, 94- 97 (Soladulcines, isol, struct) [https://doi.org/10.1055/s-0028-1101641]
  73. Uhle, F.C., JOC, 1962, 27, 656- 658 (Soladulcidine, synth) [https://doi.org/10.1021/jo01049a525]
  74. Schreiber, K., Annalen, 1964, 674, 168- 175 (Polyanine, isol)
  75. Budzikiewicz, H., Tetrahedron, 1964, 20, 2267- 2278 (Tomatidine, ms) [https://doi.org/10.1016/S0040-4020(01)97614-8]
  76. Boll, P.M. et al., Acta Chem. Scand., 1965, 19, 1365- 1370 (Soladulcidines, pmr,stereochem) [https://doi.org/10.3891/acta.chem.scand.19-1365]
  77. Schreiber, K., Annalen, 1965, 682, 219- 227 (Soladulcidine, Tomatidine, config)
  78. Schreiber, K. et al., Phytochemistry, 1966, 5, 707- 712 (Lycopersicon pimpinellifolium constits) [https://doi.org/10.1016/S0031-9422(00)83650-X]
  79. Adam, G. et al., Tetrahedron, 1966, 22, 3591- 3595 (Soladulcidine, synth) [https://doi.org/10.1016/S0040-4020(01)92547-5]
  80. Kennard, O. et al., JCS(C), 1967, 956- 964 (Tomatidine, cryst struct)
  81. Wolters, B., Planta Med., 1970, 19, 189- 193 (Soladulcidine, activity) [https://doi.org/10.1055/s-0028-1099818]
  82. Tukalo, E.A. et al., Chem. Nat. Compd. (Engl. Transl.), 1971, 7, 203 (Soladulcines, isol) [https://doi.org/10.1007/BF00568705]
  83. Roddick, J.G. et al., Phytochemistry, 1974, 13, 1459- 1462 (Tomatine, biosynth) [https://doi.org/10.1016/0031-9422(74)80307-9]
  84. Weston, R.J. et al., Aust. J. Chem., 1977, 30, 917- 921 (Tomatidine, cmr) [https://doi.org/10.1071/CH9770917]
  85. Garnero, J. et al., Riv. Ital. EPPOS, 1981, 63, 361- 364 (N-Nitrosotomatidine, isol)
  86. Osman, S.F. et al., Phytochemistry, 1986, 25, 967- 968 (Sisunine, isol) [https://doi.org/10.1016/0031-9422(86)80042-5]
  87. Willker, W. et al., Magn. Reson. Chem., 1992, 30, 645- 650 (Tomatidine, Tomatine, pmr,cmr)
  88. Nagaoka, T. et al., Phytochemistry, 1993, 34, 1153- 1155 (5α-Tomatidan-3-one, isol) [https://doi.org/10.1016/S0031-9422(00)90734-9]
  89. Lee, Y.Y. et al., Chem. Pharm. Bull., 1994, 42, 707- 709 (Soladulcines, isol) [https://doi.org/10.1248/cpb.42.707]
  90. Yahara, S. et al., Phytochemistry, 1996, 42, 169- 172 (Lycoperosides, isol) [https://doi.org/10.1016/0031-9422(95)00854-3]
  91. Maxwell, A. et al., Phytochemistry, 1996, 42, 543 (Solanum arboreum constits) [https://doi.org/10.1016/0031-9422(95)00846-2]
  92. Lee, Y.Y. et al., Chem. Pharm. Bull., 1997, 45, 1381- 1382 (Solalyratines A,B, isol) [https://doi.org/10.1248/cpb.45.1381]
  93. Friedman, M. et al., J. Agric. Food Chem., 2002, 50, 5751- 5780 (Tomatines, rev) [https://doi.org/10.1021/jf020560c]
  94. Zha, X. et al., Chem. Biodiversity, 2007, 4, 25- 31 (Soladulcidine, synth)
  95. Matsushita, S. et al., Chem. Pharm. Bull., 2007, 55, 1079- 1081 (glycosides, abs config) [https://doi.org/10.1248/cpb.55.1079]
  96. Friedman, M. et al., J. Agric. Food Chem., 2009, 57, 5727- 5733 (Tomatine, activity) [https://doi.org/10.1021/jf900364j]
  97. Ohyama, K. et al., Phytochemistry, 2013, 89, 26- 31 (biosynth) [https://doi.org/10.1016/j.phytochem.2013.01.010]
  98. Ohyawa, K. et al., Bioorg. Med. Chem. Lett., 2014, 24, 3556- 3558 (biosynth)
  99. Sax's Dangerous Properties of Industrial Materials, 11th edn., J. Wiley, 2004, THG250
[top⬆]
Antifungal Citations
  1. Feng, J. et al., Biochem. J., 2003, 376, 481- 487 (AP1) [https://doi.org/10.1042/bj20030806]
  2. Prelog, V. et al., Helv. Chim. Acta, 1944, 27, 390 (struct)
  3. Kuhn, R. et al., Chem. Ber., 1947, 80, 406; 1957, 90, 203 (Demissine)
  4. Aslanov, K.A. et al., CA, 1963, 59, 6725f (3-epimer, isol)
  5. Schreiber, K. et al., Annalen, 1964, 672, 232- 235 (3-epimer, synth)
  6. Adam, C. et al., Tetrahedron, 1964, 20, 1719 (synth) [https://doi.org/10.1016/S0040-4020(01)99172-0]
  7. Wolters, B., Planta Med., 1966, 14, 1392- 1401 (activity) [https://doi.org/10.1055/s-0028-1100066]
  8. Höhne, E. et al., Tetrahedron, 1966, 22, 673 (cryst struct) [https://doi.org/10.1016/0040-4020(66)80036-4]
  9. Osman, S.F. et al., Phytochemistry, 1976, 15, 1065 (Commersonine) [https://doi.org/10.1016/S0031-9422(00)84406-4]
  10. Radeglia, R. et al., Tet. Lett., 1977, 903 (cmr) [https://doi.org/10.1016/S0040-4039(01)92787-X]
  11. Shakirov, R. et al., Chem. Nat. Compd. (Engl. Transl.), 1996, 32, 234 (Allosolanidanol) [https://doi.org/10.1007/BF01375127]
  12. King, R.R. et al., Magn. Reson. Chem., 2012, 50, 627- 631 (Dehydrocommersonine, pmr,cmr)
  13. Zhang, Z. et al., Org. Lett., 2013, 15, 2100- 2103 (synth) [https://doi.org/10.1021/ol4004993]
  14. Zhang, Z.-D. et al., Org. Lett., 2016, 18, 3038- 3040 (synth) [https://doi.org/10.1021/acs.orglett.6b01320]
  15. Anderson, R.C. et al., JCS(C), 1977, 27- 28 (isol, abs config)
  16. Kodama, H. et al., Agric. Biol. Chem., 1985, 49, 2537- 2541 (glucoside A)
  17. Uegaki, R. et al., Phytochemistry, 1985, 20, 1567- 1568 (Nicotiana constits) [https://doi.org/10.1016/S0031-9422(00)98531-5]
  18. Uegaki, R. et al., Phytochemistry, 1988, 27, 365- 368 (3S-form) [https://doi.org/10.1016/0031-9422(88)83099-1]
  19. Iwata, C. et al., Chem. Pharm. Bull., 1989, 37, 2643- 2646 (synth) [https://doi.org/10.1248/cpb.37.2643]
  20. Nagaoka, T. et al., Z. Naturforsch., C, 2001, 56, 181- 187, 707 - 713 (Solanum aethiopicum constit) [https://doi.org/10.1515/znc-2001-9-1007]
  21. Yokose, T. et al., Biosci., Biotechnol., Biochem., 2004, 68, 2640- 2642 (3-Acetoxysolavetivone)
  22. Feng, X. et al., J. Asian Nat. Prod. Res., 2010, 12, 252- 256 (glucosides A,B)
  23. Kim, J.-Y. et al., Int. J. Mol. Sci., 2013, 14, 4349- 4360 (Peptide G2, activity)
  24. Bukhari, S.T.K. et al., JCS(C), 1969, 1073- 1079 (Rishitin, stereochem)
  25. Ishizaka, N. et al., Plant Cell Physiol., 1969, 10, 183- 192 (activity)
  26. Masamune, AT. et al., Bull. Chem. Soc. Jpn., 1977, 50, 1201- 1205, 1206 - 1216 (Rishitin,isol, struct, synth) [https://doi.org/10.1246/bcsj.50.1201]
  27. Stoessl, A. et al., Can. J. Chem., 1983, 61, 1766- 1770 (biosynth) [https://doi.org/10.1139/v83-302]
  28. Kodama, H. et al., Phytochemistry, 1984, 23, 690- 692 (sophoroside) [https://doi.org/10.1016/S0031-9422(00)80412-4]
  29. Kodama, H. et al., Agric. Biol. Chem., 1985, 49, 1527- 1528 (sophoroside, activity)
  30. Kodama, H. et al., Agric. Biol. Chem., 1985, 49, 2537- 2541 (rhamnosylglucosylglucoside)
  31. Brindle, P.A. et al., Phytochemistry, 1985, 24, 1219- 1222 (biosynth) [https://doi.org/10.1016/S0031-9422(00)81105-X]
  32. Alphey, T.J.W. et al., Rev. Nematol., 1988, 11, 399- 404 (activity)
  33. Banerjee, A.K. et al., Tetrahedron, 1993, 49, 4761- 4788 (synth, rev) [https://doi.org/10.1016/S0040-4020(01)80397-5]
  34. Chen, J. et al., Tet. Lett., 1997, 38, 1889- 1892 (synth) [https://doi.org/10.1016/S0040-4039(97)00228-1]
  35. Engstrom, K. et al., Potato Res., 1999, 42, 43- 50 (activity)
  36. Sato, Y. et al., JOC, 1969, 34, 1577- 1582 (isol, ms, ir, uv, pmr, oxo-derivs) [https://doi.org/10.1021/jo01258a010]
  37. Kusano, G. et al., JOC, 1970, 35, 2624- 2626 (synth) [https://doi.org/10.1021/jo00833a030]
  38. Katz, R. et al., CA, 1975, 83, 193635f (glycosides)
  39. Bird, G.J. et al., Aust. J. Chem., 1979, 32, 797- 816 (cmr) [https://doi.org/10.1071/CH9790797]
  40. Kusano, G. et al., Chem. Pharm. Bull., 1987, 35, 4862- 4867 (activity) [https://doi.org/10.1248/cpb.35.4862]
  41. Sato, Y. et al., JOC, 1969, 34, 1577 (ir, uv, pmr, ms) [https://doi.org/10.1021/jo01258a010]
  42. Kusano, G. et al., JOC, 1970, 35, 2624 (synth) [https://doi.org/10.1021/jo00833a030]
  43. Bird, G.J. et al., Tet. Lett., 1976, 3653 (epimer) [https://doi.org/10.1016/S0040-4039(00)92985-X]
  44. Kusano, G. et al., Chem. Pharm. Bull., 1987, 35, 4862- 4867 (activity) [https://doi.org/10.1248/cpb.35.4862]
  45. Ripperger, H. et al., Phytochemistry, 1996, 41, 1629 (20-Isosolafloridine) [https://doi.org/10.1016/0031-9422(95)00820-9]
  46. Barger, G. et al., JCS, 1936, 1537- 1542 (Solanum pseudocapsicum constit)
  47. Boll, P.M. et al., Antibiot. Annu., 1956, 3, 255- 259 (Solanocapsine, activity)
  48. Budzikiewicz, H., Tetrahedron, 1964, 20, 2267- 2278 (Solanocapsine, ms) [https://doi.org/10.1016/S0040-4020(01)97614-8]
  49. Ripperger, H. et al., Annalen, 1969, 723, 159- 180 (Solanocapsine, pmr, ir, struct)
  50. Höhne, E. et al., Tetrahedron, 1970, 26, 3569- 3577 (Solanocapsine, cryst struct) [https://doi.org/10.1016/S0040-4020(01)92936-9]
  51. Ripperger, H. et al., Tetrahedron, 1972, 28, 1629- 1644 (Solanocapsine, synth) [https://doi.org/10.1016/0040-4020(72)88045-1]
  52. Mitscher, L. et al., Experientia, 1976, 32, 415- 416 (Solacassine, activity) [https://doi.org/10.1007/BF01920766]
  53. Ali, E. et al., Tetrahedron, 1977, 33, 1371- 1377 (Solanoforthine, isol, ms) [https://doi.org/10.1016/0040-4020(77)84088-X]
  54. Bird, G.J. et al., Aust. J. Chem., 1979, 32, 797- 816 (3β-amino steroidal alkaloids, cmr, rev) [https://doi.org/10.1071/CH9790797]
  55. Chakravarty, A.K. et al., JCS Perkin 1, 1984, 467- 474 (O-Methylsolanocapsine, synth) [https://doi.org/10.1039/p19840000467]
  56. Chakravarty, A.K. et al., Phytochemistry, 1988, 27, 956- 958 (7β-Hydroxy-O-methylsolanocapsine, isol) [https://doi.org/10.1016/0031-9422(88)84135-9]
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  58. Barger, G. et al., JCS, 1936, 1537- 1542 (Solanum pseudocapsicum constit)
  59. Boll, P.M. et al., Antibiot. Annu., 1956, 3, 255- 259 (Solanocapsine, activity)
  60. Budzikiewicz, H., Tetrahedron, 1964, 20, 2267- 2278 (Solanocapsine, ms) [https://doi.org/10.1016/S0040-4020(01)97614-8]
  61. Ripperger, H. et al., Annalen, 1969, 723, 159- 180 (Solanocapsine, pmr, ir, struct)
  62. Höhne, E. et al., Tetrahedron, 1970, 26, 3569- 3577 (Solanocapsine, cryst struct) [https://doi.org/10.1016/S0040-4020(01)92936-9]
  63. Ripperger, H. et al., Tetrahedron, 1972, 28, 1629- 1644 (Solanocapsine, synth) [https://doi.org/10.1016/0040-4020(72)88045-1]
  64. Mitscher, L. et al., Experientia, 1976, 32, 415- 416 (Solacassine, activity) [https://doi.org/10.1007/BF01920766]
  65. Ali, E. et al., Tetrahedron, 1977, 33, 1371- 1377 (Solanoforthine, isol, ms) [https://doi.org/10.1016/0040-4020(77)84088-X]
  66. Bird, G.J. et al., Aust. J. Chem., 1979, 32, 797- 816 (3β-amino steroidal alkaloids, cmr, rev) [https://doi.org/10.1071/CH9790797]
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  69. Ripperger, H., Alkaloids: Chem. Biol. Perspect., 1998, 12, 103- 185 (Solanum alkaloids, rev)
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  71. Kuhn, R. et al., Chem. Ber., 1957, 90, 203- 218 (Tomatines, struct)
  72. Sato, Y. et al., JACS, 1957, 79, 6089- 6090 (Tomatidine, struct) [https://doi.org/10.1021/ja01579a069]
  73. Schreiber, K., Planta Med., 1958, 6, 94- 97 (Soladulcines, isol, struct) [https://doi.org/10.1055/s-0028-1101641]
  74. Uhle, F.C., JOC, 1962, 27, 656- 658 (Soladulcidine, synth) [https://doi.org/10.1021/jo01049a525]
  75. Schreiber, K., Annalen, 1964, 674, 168- 175 (Polyanine, isol)
  76. Budzikiewicz, H., Tetrahedron, 1964, 20, 2267- 2278 (Tomatidine, ms) [https://doi.org/10.1016/S0040-4020(01)97614-8]
  77. Boll, P.M. et al., Acta Chem. Scand., 1965, 19, 1365- 1370 (Soladulcidines, pmr,stereochem) [https://doi.org/10.3891/acta.chem.scand.19-1365]
  78. Schreiber, K., Annalen, 1965, 682, 219- 227 (Soladulcidine, Tomatidine, config)
  79. Schreiber, K. et al., Phytochemistry, 1966, 5, 707- 712 (Lycopersicon pimpinellifolium constits) [https://doi.org/10.1016/S0031-9422(00)83650-X]
  80. Adam, G. et al., Tetrahedron, 1966, 22, 3591- 3595 (Soladulcidine, synth) [https://doi.org/10.1016/S0040-4020(01)92547-5]
  81. Kennard, O. et al., JCS(C), 1967, 956- 964 (Tomatidine, cryst struct)
  82. Wolters, B., Planta Med., 1970, 19, 189- 193 (Soladulcidine, activity) [https://doi.org/10.1055/s-0028-1099818]
  83. Tukalo, E.A. et al., Chem. Nat. Compd. (Engl. Transl.), 1971, 7, 203 (Soladulcines, isol) [https://doi.org/10.1007/BF00568705]
  84. Roddick, J.G. et al., Phytochemistry, 1974, 13, 1459- 1462 (Tomatine, biosynth) [https://doi.org/10.1016/0031-9422(74)80307-9]
  85. Weston, R.J. et al., Aust. J. Chem., 1977, 30, 917- 921 (Tomatidine, cmr) [https://doi.org/10.1071/CH9770917]
  86. Garnero, J. et al., Riv. Ital. EPPOS, 1981, 63, 361- 364 (N-Nitrosotomatidine, isol)
  87. Osman, S.F. et al., Phytochemistry, 1986, 25, 967- 968 (Sisunine, isol) [https://doi.org/10.1016/0031-9422(86)80042-5]
  88. Willker, W. et al., Magn. Reson. Chem., 1992, 30, 645- 650 (Tomatidine, Tomatine, pmr,cmr)
  89. Nagaoka, T. et al., Phytochemistry, 1993, 34, 1153- 1155 (5α-Tomatidan-3-one, isol) [https://doi.org/10.1016/S0031-9422(00)90734-9]
  90. Lee, Y.Y. et al., Chem. Pharm. Bull., 1994, 42, 707- 709 (Soladulcines, isol) [https://doi.org/10.1248/cpb.42.707]
  91. Yahara, S. et al., Phytochemistry, 1996, 42, 169- 172 (Lycoperosides, isol) [https://doi.org/10.1016/0031-9422(95)00854-3]
  92. Maxwell, A. et al., Phytochemistry, 1996, 42, 543 (Solanum arboreum constits) [https://doi.org/10.1016/0031-9422(95)00846-2]
  93. Lee, Y.Y. et al., Chem. Pharm. Bull., 1997, 45, 1381- 1382 (Solalyratines A,B, isol) [https://doi.org/10.1248/cpb.45.1381]
  94. Friedman, M. et al., J. Agric. Food Chem., 2002, 50, 5751- 5780 (Tomatines, rev) [https://doi.org/10.1021/jf020560c]
  95. Zha, X. et al., Chem. Biodiversity, 2007, 4, 25- 31 (Soladulcidine, synth)
  96. Matsushita, S. et al., Chem. Pharm. Bull., 2007, 55, 1079- 1081 (glycosides, abs config) [https://doi.org/10.1248/cpb.55.1079]
  97. Friedman, M. et al., J. Agric. Food Chem., 2009, 57, 5727- 5733 (Tomatine, activity) [https://doi.org/10.1021/jf900364j]
  98. Ohyama, K. et al., Phytochemistry, 2013, 89, 26- 31 (biosynth) [https://doi.org/10.1016/j.phytochem.2013.01.010]
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  102. Kuhn, R. et al., Chem. Ber., 1957, 90, 203- 218 (Tomatines, struct)
  103. Sato, Y. et al., JACS, 1957, 79, 6089- 6090 (Tomatidine, struct) [https://doi.org/10.1021/ja01579a069]
  104. Schreiber, K., Planta Med., 1958, 6, 94- 97 (Soladulcines, isol, struct) [https://doi.org/10.1055/s-0028-1101641]
  105. Uhle, F.C., JOC, 1962, 27, 656- 658 (Soladulcidine, synth) [https://doi.org/10.1021/jo01049a525]
  106. Schreiber, K., Annalen, 1964, 674, 168- 175 (Polyanine, isol)
  107. Budzikiewicz, H., Tetrahedron, 1964, 20, 2267- 2278 (Tomatidine, ms) [https://doi.org/10.1016/S0040-4020(01)97614-8]
  108. Boll, P.M. et al., Acta Chem. Scand., 1965, 19, 1365- 1370 (Soladulcidines, pmr,stereochem) [https://doi.org/10.3891/acta.chem.scand.19-1365]
  109. Schreiber, K., Annalen, 1965, 682, 219- 227 (Soladulcidine, Tomatidine, config)
  110. Schreiber, K. et al., Phytochemistry, 1966, 5, 707- 712 (Lycopersicon pimpinellifolium constits) [https://doi.org/10.1016/S0031-9422(00)83650-X]
  111. Adam, G. et al., Tetrahedron, 1966, 22, 3591- 3595 (Soladulcidine, synth) [https://doi.org/10.1016/S0040-4020(01)92547-5]
  112. Kennard, O. et al., JCS(C), 1967, 956- 964 (Tomatidine, cryst struct)
  113. Wolters, B., Planta Med., 1970, 19, 189- 193 (Soladulcidine, activity) [https://doi.org/10.1055/s-0028-1099818]
  114. Tukalo, E.A. et al., Chem. Nat. Compd. (Engl. Transl.), 1971, 7, 203 (Soladulcines, isol) [https://doi.org/10.1007/BF00568705]
  115. Roddick, J.G. et al., Phytochemistry, 1974, 13, 1459- 1462 (Tomatine, biosynth) [https://doi.org/10.1016/0031-9422(74)80307-9]
  116. Weston, R.J. et al., Aust. J. Chem., 1977, 30, 917- 921 (Tomatidine, cmr) [https://doi.org/10.1071/CH9770917]
  117. Garnero, J. et al., Riv. Ital. EPPOS, 1981, 63, 361- 364 (N-Nitrosotomatidine, isol)
  118. Osman, S.F. et al., Phytochemistry, 1986, 25, 967- 968 (Sisunine, isol) [https://doi.org/10.1016/0031-9422(86)80042-5]
  119. Willker, W. et al., Magn. Reson. Chem., 1992, 30, 645- 650 (Tomatidine, Tomatine, pmr,cmr)
  120. Nagaoka, T. et al., Phytochemistry, 1993, 34, 1153- 1155 (5α-Tomatidan-3-one, isol) [https://doi.org/10.1016/S0031-9422(00)90734-9]
  121. Lee, Y.Y. et al., Chem. Pharm. Bull., 1994, 42, 707- 709 (Soladulcines, isol) [https://doi.org/10.1248/cpb.42.707]
  122. Yahara, S. et al., Phytochemistry, 1996, 42, 169- 172 (Lycoperosides, isol) [https://doi.org/10.1016/0031-9422(95)00854-3]
  123. Maxwell, A. et al., Phytochemistry, 1996, 42, 543 (Solanum arboreum constits) [https://doi.org/10.1016/0031-9422(95)00846-2]
  124. Lee, Y.Y. et al., Chem. Pharm. Bull., 1997, 45, 1381- 1382 (Solalyratines A,B, isol) [https://doi.org/10.1248/cpb.45.1381]
  125. Friedman, M. et al., J. Agric. Food Chem., 2002, 50, 5751- 5780 (Tomatines, rev) [https://doi.org/10.1021/jf020560c]
  126. Zha, X. et al., Chem. Biodiversity, 2007, 4, 25- 31 (Soladulcidine, synth)
  127. Matsushita, S. et al., Chem. Pharm. Bull., 2007, 55, 1079- 1081 (glycosides, abs config) [https://doi.org/10.1248/cpb.55.1079]
  128. Friedman, M. et al., J. Agric. Food Chem., 2009, 57, 5727- 5733 (Tomatine, activity) [https://doi.org/10.1021/jf900364j]
  129. Ohyama, K. et al., Phytochemistry, 2013, 89, 26- 31 (biosynth) [https://doi.org/10.1016/j.phytochem.2013.01.010]
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  133. Kuhn, R. et al., Chem. Ber., 1957, 90, 203- 218 (Tomatines, struct)
  134. Sato, Y. et al., JACS, 1957, 79, 6089- 6090 (Tomatidine, struct) [https://doi.org/10.1021/ja01579a069]
  135. Schreiber, K., Planta Med., 1958, 6, 94- 97 (Soladulcines, isol, struct) [https://doi.org/10.1055/s-0028-1101641]
  136. Uhle, F.C., JOC, 1962, 27, 656- 658 (Soladulcidine, synth) [https://doi.org/10.1021/jo01049a525]
  137. Schreiber, K., Annalen, 1964, 674, 168- 175 (Polyanine, isol)
  138. Budzikiewicz, H., Tetrahedron, 1964, 20, 2267- 2278 (Tomatidine, ms) [https://doi.org/10.1016/S0040-4020(01)97614-8]
  139. Boll, P.M. et al., Acta Chem. Scand., 1965, 19, 1365- 1370 (Soladulcidines, pmr,stereochem) [https://doi.org/10.3891/acta.chem.scand.19-1365]
  140. Schreiber, K., Annalen, 1965, 682, 219- 227 (Soladulcidine, Tomatidine, config)
  141. Schreiber, K. et al., Phytochemistry, 1966, 5, 707- 712 (Lycopersicon pimpinellifolium constits) [https://doi.org/10.1016/S0031-9422(00)83650-X]
  142. Adam, G. et al., Tetrahedron, 1966, 22, 3591- 3595 (Soladulcidine, synth) [https://doi.org/10.1016/S0040-4020(01)92547-5]
  143. Kennard, O. et al., JCS(C), 1967, 956- 964 (Tomatidine, cryst struct)
  144. Wolters, B., Planta Med., 1970, 19, 189- 193 (Soladulcidine, activity) [https://doi.org/10.1055/s-0028-1099818]
  145. Tukalo, E.A. et al., Chem. Nat. Compd. (Engl. Transl.), 1971, 7, 203 (Soladulcines, isol) [https://doi.org/10.1007/BF00568705]
  146. Roddick, J.G. et al., Phytochemistry, 1974, 13, 1459- 1462 (Tomatine, biosynth) [https://doi.org/10.1016/0031-9422(74)80307-9]
  147. Weston, R.J. et al., Aust. J. Chem., 1977, 30, 917- 921 (Tomatidine, cmr) [https://doi.org/10.1071/CH9770917]
  148. Garnero, J. et al., Riv. Ital. EPPOS, 1981, 63, 361- 364 (N-Nitrosotomatidine, isol)
  149. Osman, S.F. et al., Phytochemistry, 1986, 25, 967- 968 (Sisunine, isol) [https://doi.org/10.1016/0031-9422(86)80042-5]
  150. Willker, W. et al., Magn. Reson. Chem., 1992, 30, 645- 650 (Tomatidine, Tomatine, pmr,cmr)
  151. Nagaoka, T. et al., Phytochemistry, 1993, 34, 1153- 1155 (5α-Tomatidan-3-one, isol) [https://doi.org/10.1016/S0031-9422(00)90734-9]
  152. Lee, Y.Y. et al., Chem. Pharm. Bull., 1994, 42, 707- 709 (Soladulcines, isol) [https://doi.org/10.1248/cpb.42.707]
  153. Yahara, S. et al., Phytochemistry, 1996, 42, 169- 172 (Lycoperosides, isol) [https://doi.org/10.1016/0031-9422(95)00854-3]
  154. Maxwell, A. et al., Phytochemistry, 1996, 42, 543 (Solanum arboreum constits) [https://doi.org/10.1016/0031-9422(95)00846-2]
  155. Lee, Y.Y. et al., Chem. Pharm. Bull., 1997, 45, 1381- 1382 (Solalyratines A,B, isol) [https://doi.org/10.1248/cpb.45.1381]
  156. Friedman, M. et al., J. Agric. Food Chem., 2002, 50, 5751- 5780 (Tomatines, rev) [https://doi.org/10.1021/jf020560c]
  157. Zha, X. et al., Chem. Biodiversity, 2007, 4, 25- 31 (Soladulcidine, synth)
  158. Matsushita, S. et al., Chem. Pharm. Bull., 2007, 55, 1079- 1081 (glycosides, abs config) [https://doi.org/10.1248/cpb.55.1079]
  159. Friedman, M. et al., J. Agric. Food Chem., 2009, 57, 5727- 5733 (Tomatine, activity) [https://doi.org/10.1021/jf900364j]
  160. Ohyama, K. et al., Phytochemistry, 2013, 89, 26- 31 (biosynth) [https://doi.org/10.1016/j.phytochem.2013.01.010]
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  164. Kuhn, R. et al., Chem. Ber., 1957, 90, 203- 218 (Tomatines, struct)
  165. Sato, Y. et al., JACS, 1957, 79, 6089- 6090 (Tomatidine, struct) [https://doi.org/10.1021/ja01579a069]
  166. Schreiber, K., Planta Med., 1958, 6, 94- 97 (Soladulcines, isol, struct) [https://doi.org/10.1055/s-0028-1101641]
  167. Uhle, F.C., JOC, 1962, 27, 656- 658 (Soladulcidine, synth) [https://doi.org/10.1021/jo01049a525]
  168. Schreiber, K., Annalen, 1964, 674, 168- 175 (Polyanine, isol)
  169. Budzikiewicz, H., Tetrahedron, 1964, 20, 2267- 2278 (Tomatidine, ms) [https://doi.org/10.1016/S0040-4020(01)97614-8]
  170. Boll, P.M. et al., Acta Chem. Scand., 1965, 19, 1365- 1370 (Soladulcidines, pmr,stereochem) [https://doi.org/10.3891/acta.chem.scand.19-1365]
  171. Schreiber, K., Annalen, 1965, 682, 219- 227 (Soladulcidine, Tomatidine, config)
  172. Schreiber, K. et al., Phytochemistry, 1966, 5, 707- 712 (Lycopersicon pimpinellifolium constits) [https://doi.org/10.1016/S0031-9422(00)83650-X]
  173. Adam, G. et al., Tetrahedron, 1966, 22, 3591- 3595 (Soladulcidine, synth) [https://doi.org/10.1016/S0040-4020(01)92547-5]
  174. Kennard, O. et al., JCS(C), 1967, 956- 964 (Tomatidine, cryst struct)
  175. Wolters, B., Planta Med., 1970, 19, 189- 193 (Soladulcidine, activity) [https://doi.org/10.1055/s-0028-1099818]
  176. Tukalo, E.A. et al., Chem. Nat. Compd. (Engl. Transl.), 1971, 7, 203 (Soladulcines, isol) [https://doi.org/10.1007/BF00568705]
  177. Roddick, J.G. et al., Phytochemistry, 1974, 13, 1459- 1462 (Tomatine, biosynth) [https://doi.org/10.1016/0031-9422(74)80307-9]
  178. Weston, R.J. et al., Aust. J. Chem., 1977, 30, 917- 921 (Tomatidine, cmr) [https://doi.org/10.1071/CH9770917]
  179. Garnero, J. et al., Riv. Ital. EPPOS, 1981, 63, 361- 364 (N-Nitrosotomatidine, isol)
  180. Osman, S.F. et al., Phytochemistry, 1986, 25, 967- 968 (Sisunine, isol) [https://doi.org/10.1016/0031-9422(86)80042-5]
  181. Willker, W. et al., Magn. Reson. Chem., 1992, 30, 645- 650 (Tomatidine, Tomatine, pmr,cmr)
  182. Nagaoka, T. et al., Phytochemistry, 1993, 34, 1153- 1155 (5α-Tomatidan-3-one, isol) [https://doi.org/10.1016/S0031-9422(00)90734-9]
  183. Lee, Y.Y. et al., Chem. Pharm. Bull., 1994, 42, 707- 709 (Soladulcines, isol) [https://doi.org/10.1248/cpb.42.707]
  184. Yahara, S. et al., Phytochemistry, 1996, 42, 169- 172 (Lycoperosides, isol) [https://doi.org/10.1016/0031-9422(95)00854-3]
  185. Maxwell, A. et al., Phytochemistry, 1996, 42, 543 (Solanum arboreum constits) [https://doi.org/10.1016/0031-9422(95)00846-2]
  186. Lee, Y.Y. et al., Chem. Pharm. Bull., 1997, 45, 1381- 1382 (Solalyratines A,B, isol) [https://doi.org/10.1248/cpb.45.1381]
  187. Friedman, M. et al., J. Agric. Food Chem., 2002, 50, 5751- 5780 (Tomatines, rev) [https://doi.org/10.1021/jf020560c]
  188. Zha, X. et al., Chem. Biodiversity, 2007, 4, 25- 31 (Soladulcidine, synth)
  189. Matsushita, S. et al., Chem. Pharm. Bull., 2007, 55, 1079- 1081 (glycosides, abs config) [https://doi.org/10.1248/cpb.55.1079]
  190. Friedman, M. et al., J. Agric. Food Chem., 2009, 57, 5727- 5733 (Tomatine, activity) [https://doi.org/10.1021/jf900364j]
  191. Ohyama, K. et al., Phytochemistry, 2013, 89, 26- 31 (biosynth) [https://doi.org/10.1016/j.phytochem.2013.01.010]
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  196. Bianchi, E. et al., CA, 1961, 55, 26002g (Isosolasonine)
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  201. Boll, P.M. et al., Acta Chem. Scand., 1965, 19, 1365- 1370 (pmr, config) [https://doi.org/10.3891/acta.chem.scand.19-1365]
  202. Bognár, R. et al., Pharmazie, 1965, 20, 40- 42 (Solavilline)
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Trypanocidal Citations
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Anthelmintic Citations
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Anticancer Citations
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