The University of Massachusetts Amherst

The Plant Cell Culture Library

Khaya anthotheca
Cell Line ID KA-12939
Media Type B122
Availability Low
Order Sapindales
Family Meliaceae
Genus Khaya
Antifungal Genus Level ➡ 2 citations
Trypanocidal Genus Level ➡ 3 citations
Anthelmintic Genus Level ➡ 2 citations
Insecticidal Genus Level ➡ 16 citations
Anticancer Genus Level
Culture Initiation Site Dusseldorf
Plant Habit Tree
Plant Habitat Tropical
Culture Start Material Seed
Native Range Topical Africa
Plant Supplier Inst/Nat. Tree Seed Programme
Antifungal Citations
  1. Abdelgaleil SA, Hashinaga F, Nakatani M. Antifungal activity of limonoids from Khaya ivorensis. Pest Manag Sci. 2005 Feb;61(2):186-90. PubMed PMID: 15619711.
  2. Abdelgaleil SA, Iwagawa T, Doe M, Nakatani M. Antifungal limonoids from the fruits of Khaya senegalensis. Fitoterapia. 2004 Sep;75(6):566-72. PubMed PMID: 15351110.
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Trypanocidal Citations
  1. Ibrahim MA, Musa AM, Aliyu AB, Mayaki HS, Gideon A, Islam MS. Phenolics-rich fraction of Khaya senegalensis stem bark: antitrypanosomal activity and amelioration of some parasite-induced pathological changes. Pharm Biol. 2013 Jul;51(7):906-13. [https://doi.org/10.3109/13880209.2013.771191.] Epub 2013 Apr 29. PubMed PMID: 23627467.
  2. Obbo CJ, Makanga B, Mulholland DA, Coombes PH, Brun R. Antiprotozoal activity of Khaya anthotheca, (Welv.) C.D.C. a plant used by chimpanzees for self-medication. J Ethnopharmacol. 2013 May 2;147(1):220-3. [https://doi.org/10.1016/j.jep.2013.03.007.] Epub 2013 Mar 14. PubMed PMID: 23501156.
  3. Owolabi OA, Makanga B, Thomas EW, Molyneux DH, Oliver RW. Trypanocidal potentials of African woody plants: in vitro trial of Khaya grandifoliola seed extracts against Trypanosoma brucei brucei. J Ethnopharmacol. 1990 Sep;30(2):227-31. PubMed PMID: 2255214.
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Anthelmintic Citations
  1. Ademola IO, Fagbemi BO, Idowu SO. Bioseparation and activity of Khaya senegalensis fractions against infective larvae of Haemonchus contortus. Vet Parasitol. 2009 Oct 28;165(1-2):170-4. [https://doi.org/10.1016/j.vetpar.2009.06.029.] Epub 2009 Jul 2. PubMed PMID: 19625127.
  2. Ademola IO, Fagbemi BO, Idowu SO. Evaluation of the anthelmintic activity of Khaya senegalensis extract against gastrointestinal nematodes of sheep: in vitro and in vivo studies. Vet Parasitol. 2004 Jun 21;122(2):151-64. PubMed PMID: 15177720.
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Insecticidal Citations
  1. Bevan, C.W.L. et al., JCS, 1962, 768- 771 (Khivorin)
  2. Bevan, C.W.L. et al., JCS, 1963, 980- 982 (7-Deacetoxy-7-oxokhivorin)
  3. Akisanya, A. et al., JCS(C), 1966, 506- 509 (Khivorin, struct)
  4. Taylor, D.A.H. et al., Chem. Comm., 1967, 500- 501 (Nyasin)
  5. Adesogan, E.K. et al., JCS(C), 1967, 554- 556 (Khaya senegalensis constits)
  6. Baldwin, M.A. et al., JCS(C), 1967, 1026- 1034 (ms)
  7. Taylor, D.A.H., Chem. Comm., 1968, 1172 (11β-Acetoxykhivorin)
  8. Buchanan, J.G.St.C. et al., Chem. Comm., 1969, 1493 (synth) [https://doi.org/10.1039/C29690001493]
  9. Adesogan, E.K. et al., JCS(C), 1970, 205- 211 (Khaya anthotheca constits)
  10. Taylor, D.A.H. et al., JCS(C), 1970, 336- 337 (11β-Acetoxykhivorin)
  11. Ekong, D.E.U. et al., JCS Perkin 1, 1972, 653- 655 (pmr) [https://doi.org/10.1039/p19720000653]
  12. Connolly, J.D. et al., JCS Perkin 1, 1973, 686- 687 (Nyasin, struct) [https://doi.org/10.1039/p19730000686]
  13. Tchimene, M.K. et al., Bull. Chem. Soc. Ethiop., 2006, 20, 69- 73 (3,7-Dideacetyl-6-hydroxykhivorin)
  14. Zhang, H. et al., Acta Cryst. E, 2007, 63, o4599 (3,7-Dideacetylkhivorin, cryst struct)
  15. Zhang, H. et al., Acta Cryst. E, 2007, 63, o4162 (1,3,7-Trideacetylkhivorin, cryst struct)
  16. Narender, T. et al., Nat. Prod. Res., 2008, 22, 763- 800 (cmr)
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