The University of Massachusetts Amherst

The Plant Cell Culture Library

Arnica sachalinensis
Cell Line ID AS-07953
Media Type B89
Lowest Tolerable USDA Zone 2a
Drought Tolerance Not tolerant
Availability Low
Order Asterales
Family Compositae
Genus Arnica
Antibacterial Genus Level ➡ 38 citations
Antifungal Genus Level ➡ 3 citations
Insecticidal Genus Level
Culture Initiation Site Lausanne
Plant Habit Herb Perennial
Plant Habitat Arctic/Cool Temp
Culture Start Material Shoot
Native Range Sakhalin Islands, Northeast Siberia
Plant Supplier Botanical Garden Lausanne
Antibacterial Citations
  1. Herz, W. et al., JACS, 1963, 85, 19- 26 (Helenalin, Balduilin, struct) [https://doi.org/10.1021/ja00884a004]
  2. Dominguez, E. et al., Tetrahedron, 1963, 19, 1415- 1421 (Mexicanin I) [https://doi.org/10.1016/S0040-4020(01)98567-9]
  3. Herz, W. et al., Tetrahedron, 1963, 21, 1711- 1715; 1966, 22, 1907 - 1915 (Bigelovin,Gaillardia constits) [https://doi.org/10.1016/S0040-4020(01)98641-7]
  4. Mazhar-Ul-Haq, et al.JCS(B), 1969, 956- 960 (Helenalin, cryst struct)
  5. Lee, K.-H. et al., J. Pharm. Sci., 1972, 61, 626- 628 (Angustibalin) [https://doi.org/10.1002/jps.2600610431]
  6. Pettit, G.R., J. Med. Chem., 1974, 17, 1013- 1016 (Helenalin, activity) [https://doi.org/10.1021/jm00255a024]
  7. Ohfune, Y. et al., JACS, 1978, 100, 5946- 5948 (Helenalin, synth, bibl) [https://doi.org/10.1021/ja00486a059]
  8. Roberts, M.R. et al., JACS, 1979, 101, 7626- 7627 (Helenalin, synth) [https://doi.org/10.1021/ja00519a032]
  9. Bohlmann, F. et al., Phytochemistry, 1981, 20, 1146- 1148; 1985, 24, 1315 - 1318 (Kingiolide, 6-Hydroxyaromatin) [https://doi.org/10.1016/0031-9422(81)83050-6]
  10. Grieco, P.A. et al., JOC, 1983, 48, 360- 366 (Bigelovin, Mexicanin I, Linifolin A, synth) [https://doi.org/10.1021/jo00151a016]
  11. Watanabe, K. et al., J. Agric. Food Chem., 1985, 33, 83- 86 (Quadridenin) [https://doi.org/10.1021/jf00061a024]
  12. Romo De Vivar, A. et al., J. Nat. Prod., 1987, 50, 284- 286 (Linifolin A cryst struct) [https://doi.org/10.1021/np50050a037]
  13. Watson, W.H. et al., Acta Cryst. C, 1990, 46, 1524- 1528 (Helenalin, Mexicanin I, cryst struct) [https://doi.org/10.1107/S0108270189013387]
  14. Gao, F. et al., Phytochemistry, 1990, 29, 895- 899 (Villosin A) [https://doi.org/10.1016/0031-9422(90)80041-E]
  15. Silva, G.L. et al., Phytochemistry, 1992, 31, 1621- 1630 (8-Epihelenalin angelate) [https://doi.org/10.1016/0031-9422(92)83118-I]
  16. Powis, G. et al., Cancer Chemother. Pharmacol., 1994, 34, 344- 350 (Helenalin, activity)
  17. Enriz, R.D. et al., Drug Des. Discovery, 1994, 11, 23 (Helenalin, pharmacol, sar)
  18. Robles, M. et al., Planta Med., 1995, 61, 199- 203 (Helenalin, activity, rev) [https://doi.org/10.1055/s-2006-958055]
  19. Wang, Q. et al., Planta Med., 1996, 62, 166- 168 (Bigelovin, pmr, cmr, activity) [https://doi.org/10.1055/s-2006-957843]
  20. Money, T. et al., Tetrahedron, 1996, 52, 6307- 6324 (synth) [https://doi.org/10.1016/0040-4020(96)00284-0]
  21. Park, E.J. et al., Planta Med., 1998, 64, 752- 754 (Inula britannica constits, activity) [https://doi.org/10.1055/s-2006-957573]
  22. Ramanandraibe, V. et al., J. Nat. Prod., 2005, 68, 800- 803 (Vernoniopsis caudata constits) [https://doi.org/10.1021/np0401866]
  23. Nam, K.W. et al., J. Ethnopharmacol., 2009, 123, 250- 256 (Bigelovin, activity) [https://doi.org/10.1016/j.jep.2009.03.017]
  24. Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, HAK300
  25. Wollenweber, E. et al., Biochimie, 1971, 53, 935- 938 (Betuletol, struct) [https://doi.org/10.1016/S0300-9084(71)80157-8]
  26. Wollenweber, E. et al., Phytochemistry, 1974, 13, 2318- 2319 (Alnus sp. constit) [https://doi.org/10.1016/0031-9422(74)85049-1]
  27. Wollenweber, E., Biochem. Syst. Ecol., 1975, 3, 47- 52 (Betuletol, occur) [https://doi.org/10.1016/0305-1978(75)90040-X]
  28. Wagner, H. et al., Tetrahedron, 1977, 33, 1411- 1414 (Betuletol, synth, bibl) [https://doi.org/10.1016/0040-4020(77)84093-3]
  29. Goudard, M. et al., Phytochemistry, 1978, 17, 145- 146 (Betuletol, ms) [https://doi.org/10.1016/S0031-9422(00)89698-3]
  30. Wollenweber, E. et al., Phytochemistry, 1981, 20, 869- 932 (Betuletol, occur, rev) [https://doi.org/10.1016/0031-9422(81)83001-4]
  31. Merfort, I., Planta Med., 1984, 107 (Betuletol, isol) [https://doi.org/10.1055/s-2007-969637]
  32. Merfort, I., Planta Med., 1985, 51, 136- 138 (Betuletol, occur, isol) [https://doi.org/10.1055/s-2007-969428]
  33. Nair, A.G.R. et al., Phytochemistry, 1990, 29, 1011- 1012 (Betuletrin, struct) [https://doi.org/10.1016/0031-9422(90)80074-Q]
  34. Merfort, I. et al., Planta Med., 1992, 58, 355- 357 (3-glucoside, struct) [https://doi.org/10.1055/s-2006-961484]
  35. Mahato, S.B. et al., Tetrahedron, 1994, 50, 9439- 9446 (Camaraside, struct) [https://doi.org/10.1016/S0040-4020(01)85518-6]
  36. Lee, K.H. et al., Heterocycles, 2008, 75, 419- 426 (Tetragonia tetragonoides constit)
  37. Patil, G. et al., Int. J. Pharm. Sci. Res., 2012, 3, 835- 839 (chicory constit)
  38. Rashid, F. et al., J. Chem. Soc. Pak., 2013, 35, 905- 910 (apricot constit, activity)
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Antifungal Citations
  1. Stanciuc AM, Gaspar A, Moldovan L, Saviuc C, Popa M, Măruţescu L. In vitro antimicrobial activity of Romanian medicinal plants hydroalcoholic extracts on planktonic and adhered cells. Roum Arch Microbiol Immunol. 2011 Jan-Mar;70(1):11-4. PubMed PMID: 21717806.
  2. Tabanca N, Demirci B, Crockett SL, Başer KH, Wedge DE. Chemical composition and antifungal activity of Arnica longifolia, Aster hesperius, and Chrysothamnus nauseosus essential oils. J Agric Food Chem. 2007 Oct 17;55(21):8430-5. Epub 2007 Sep 26. PubMed PMID: 17894463.
  3. Koo H, Gomes BP, Rosalen PL, Ambrosano GM, Park YK, Cury JA. In vitro antimicrobial activity of propolis and Arnica montana against oral pathogens. Arch Oral Biol. 2000 Feb;45(2):141-8. PubMed PMID: 10716618.
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