The Plant Cell Culture Library
Ailanthus altissima
Cell Line ID AA-13605 C1
Media Type B50
Availability Medium
Order Sapindales
Family Simaroubaceae
Genus Ailanthus
Antifungal Genus Level ➡ 36 citations
Anthelmintic Genus Level ➡ 1 citations
Insecticidal Species Level ➡ 56 citations
Anticancer Species Level ➡ 56 citations
Common Names Tree Of Heaven
Culture Initiation Site Dusseldorf
Plant Habit Tree deciduous
Plant Habitat Temperate
Culture Start Material Seed
Native Range North China
Plant Supplier Comm/Chiltern Seeds
Antifungal Citations
- Pinto, A.V. et al., Ann. Acad. Bras. Ciènc., 1982, 54, 1 (synth)
- Rao, M.M. et al., J. Nat. Prod., 1982, 45, 600- 604 (Tabebuia cassinoides constits) [https://doi.org/10.1021/np50023a014]
- Lopes, C.C. et al., J. Het. Chem., 1984, 21, 621- 622 (synth, uv, pmr, bibl)
- Wagner, H. et al., Helv. Chim. Acta, 1989, 72, 659- 667 (Tabebuia avellandae constits)
- Zani, C.L. et al., Phytochemistry, 1991, 30, 2379- 2381 (Tabebuia ochracea constits, 6-methoxy) [https://doi.org/10.1016/0031-9422(91)83653-3]
- Braga de Oliveira, A. et al., Phytochemistry, 1993, 34, 1409- 1412 (Tabebuia incana constits) [https://doi.org/10.1016/0031-9422(91)80039-4]
- Kosuge, K. et al., Chem. Pharm. Bull., 1994, 42, 1669- 1671 (Ailanthus integrifolia constits) [https://doi.org/10.1248/cpb.42.1669]
- Diaz, F. et al., J. Nat. Prod., 1996, 59, 423- 424 (5-hydroxy-1'ξ-alcohol, 7-methoxy, 7-methoxy-1'ξ-alcohol) [https://doi.org/10.1021/np9602022]
- Koyanagi, J. et al., J. Het. Chem., 1997, 34, 407- 412 (synth)
- Hagiwara, H. et al., Heterocycles, 1999, 51, 497- 500 (synth) [https://doi.org/10.3987/COM-98-8430]
- Moideen, S.V.K. et al., Planta Med., 1999, 65, 536- 540 (1'-alcohol, activity) [https://doi.org/10.1055/s-1999-14011]
- Rodriguez, E.C. et al., Rev. Latinoam. Quim., 2000, 27, 89
- Lee, Y.R. et al., Synth. Commun., 2001, 31, 381- 386 (1'-alcohol, synth, ir, pmr)
- Fotsing, M.T. et al., Planta Med., 2003, 69, 767- 770 (7-methoxy)
- Takano, A. et al., Anticancer Res., 2009, 29, 455- 464 (pharmacol)
- Fotsing, M.T. et al., Rasayan J. Chem., 2011, 4, 242- 244 (6,7-dimethoxy)
- Haynes, H.F. et al., Aust. J. Sci. Res., Ser. A, 1952, 5, 387- 400 (isol, uv, struct, oxide)
- Cannon, J.R. et al., Aust. J. Chem., 1956, 6, 86- 89 (isol) [https://doi.org/10.1071/CH9530086]
- Rosenkranz, H.J. et al., Annalen, 1966, 691, 159- 164 (synth, uv, ir)
- Mitscher, L.A. et al., Heterocycles, 1975, 3, 7- 14 (synth) [https://doi.org/10.3987/R-1975-01-0007]
- Oehl, R. et al., Chem. Ber., 1976, 109, 705- 709 (synth, uv, ir, ms)
- Ohmoto, T. et al., Chem. Pharm. Bull., 1976, 24, 1532- 1536; 1981, 29, 390 - 395 (isol, uv,ir, pmr, ms, synth, oxide) [https://doi.org/10.1248/cpb.24.1532]
- Campos, O. et al., Heterocycles, 1980, 14, 975- 984 (synth)
- Forgacs, P. et al., Planta Med., 1982, 46, 187- 189 (isol) [https://doi.org/10.1055/s-2007-971212]
- Anderson, L.A. et al., J. Nat. Prod., 1983, 46, 374- 378 (isol, biochem) [https://doi.org/10.1021/np50027a014]
- Cain, M. et al., JACS, 1983, 105, 907- 913 (synth) [https://doi.org/10.1021/ja00342a045]
- Aragozzini, F. et al., Plant Cell Rep., 1988, 7, 213- 215 (biosynth) [https://doi.org/10.1007/BF00269327]
- Ohmoto, T. et al., Alkaloids (Academic Press), 1989, 36, 135- 170 (rev)
- He, W. et al., Meded. Fac. Landbouwwet., Rijksuniv. Gent, 1998, 64, 565- 569 (activity)
- Rossler, U. et al., Tet. Lett., 1999, 40, 7075- 7078 (synth) [https://doi.org/10.1016/S0040-4039(99)01472-0]
- Czerwinski, K.M. et al., Synth. Commun., 2003, 33, 1225- 1231 (synth, pmr, cmr)
- Bröckelmann, M.G. et al., Eur. J. Org. Chem., 2004, 4856- 4863 (isol, pmr, cmr, ms)
- Soriano-Agatón, F. et al., J. Nat. Prod., 2005, 68, 1581- 1587 (synth, pmr, cmr) [https://doi.org/10.1021/np050250z]
- Suzuki, H. et al., Synthesis, 2005, 28- 31 (synth, ir, pmr, cmr)
- Gollner, A. et al., Org. Lett., 2010, 12, 1352- 1355 (synth, ir, pmr, cmr, ms) [https://doi.org/10.1021/ol100300s]
- Dai, J. et al., Molecules, 2016, 21, 493:1- 13 (Canthin-6-ones, rev, synth, biosynth, activity)
Anthelmintic Citations
- Caboni P, Ntalli NG, Aissani N, Cavoski I, Angioni A. Nematicidal activity of (E,E)-2,4-decadienal and (E)-2-decenal from Ailanthus altissima against Meloidogyne javanica. J Agric Food Chem. 2012 Feb 1;60(4):1146-51. [https://doi.org/10.1021/jf2044586.] Epub 2012 Jan 19. PubMed PMID: 22224661.
Insecticidal Citations
- Ham, A. et al., JACS, 1954, 76, 6066- 6068 (Glaucarubin, isol, ir) [https://doi.org/10.1021/ja01652a060]
- US Pat., 1958, 2 864 745 (Glaucarubin, amoebicidal activity)
- Polonsky, J. et al., Bull. Soc. Chim. Fr., 1964, 1818- 1826, 1827 - 1835; 1965, 2793 - 2799 (Glaucarubin, Glaucarubolone, pmr, struct)
- Kartha, G. et al., JACS, 1964, 86, 3630- 3634 (Glaucarubin, cryst struct) [https://doi.org/10.1021/ja01072a008]
- Polonsky, J. et al., Tet. Lett., 1964, 5, 3983- 3990 (Ailanthone, Ailanthinone) [https://doi.org/10.1016/S0040-4039(01)89352-7]
- Casinovi, G.G. et al., Tet. Lett., 1964, 5, 3991- 3997 (Ailanthinone, struct) [https://doi.org/10.1016/S0040-4039(01)89353-9]
- Polonsky, J. et al., Bull. Soc. Chim. Fr., 1965, 2793- 2799 (Chaparrinone)
- De Mayo, P. et al., Can. J. Chem., 1965, 43, 2996- 3007, 3008 - 3017 (Chaparrin)
- Nyburg, S.C. et al., Chem. Comm., 1965, 203- 204 (Glaucarubin, abs config)
- Moron, J. et al., Tet. Lett., 1965, 9, 385- 390 (Simaroubaceae terpenoids, biosynth) [https://doi.org/10.1016/S0040-4039(01)98767-2]
- Fourrey, J.L. et al., Org. Mass Spectrom., 1968, 1, 819- 833 (ms)
- Gaudemer, A. et al., Phytochemistry, 1968, 4, 149- 153 (Glaucarubolone, Glaucarubinone,struct) [https://doi.org/10.1016/S0031-9422(00)86157-9]
- Stöcklin, W. et al., Phytochemistry, 1969, 8, 1565- 1569 (Glaucarubol, struct) [https://doi.org/10.1016/S0031-9422(00)85931-2]
- Moron, J. et al., Phytochemistry, 1971, 10, 585- 592 (Glaucarubolone, Glaucarubinone,biosynth) [https://doi.org/10.1016/S0031-9422(00)94702-2]
- Kupchan, S.M. et al., JOC, 1975, 40, 654- 656 (Ailanthinone, Dehydroailanthinone, 2'S-Acetylglaucarubinone, struct) [https://doi.org/10.1021/jo00893a024]
- Polonsky, J. et al., JOC, 1975, 40, 2499- 2504 (cmr) [https://doi.org/10.1021/jo00905a017]
- Gottlieb, H.E. et al., JOC, 1975, 40, 2499- 2504 (Ailanthinone, Glaucarubinone, cmr)
- Kupchan, S.M. et al., J. Med. Chem., 1976, 19, 1130- 1133 (Glaucarubolone esters, sar) [https://doi.org/10.1021/jm00231a009]
- Ogura, M. et al., J. Nat. Prod., 1977, 40, 579- 584 (2'-Acetylglaucarubin)
- Polonsky, J. et al., Experientia, 1978, 34, 1122- 1123 (13,18-Dehydroglaucarubinone)
- Polonsky, J. et al., C. R. Seances Acad. Sci., Ser. C, 1979, 288, 269- 271 (Castelanone,struct)
- Khan, S.A. et al., Indian J. Chem., Sect. B, 1980, 19, 183- 184 (Excelsin, struct)
- Khan, S.A. et al., Phytochemistry, 1980, 19, 2484- 2485 (13,18-Dehydroexcelsin) [https://doi.org/10.1016/S0031-9422(00)91062-8]
- Tri, M.V. et al., J. Nat. Prod., 1981, 44, 279- 284 (Soularubinone, struct, activity)
- Naora, H. et al., Chem. Pharm. Bull., 1983, 56, 3694- 3698 (Shinjulactone A, Ailanthone,cryst struct)
- Handa, S.S. et al., J. Nat. Prod., 1983, 46, 359- 364 (Holacanthone, struct, activity) [https://doi.org/10.1021/np50027a011]
- Ishibashi, M. et al., Bull. Chem. Soc. Jpn., 1984, 57, 2484- 2489, 2496-2501 (Shinjulactone D, Shinjuglycosides)
- Waterman, P.G. et al., Planta Med., 1984, 50, 261- 263 (Odyendyea gabonensis constits) [https://doi.org/10.1055/s-2007-969694]
- Bhatnagar, S. et al., Tet. Lett., 1984, 25, 299- 302 (Simarouba glauca constits, cryst struct) [https://doi.org/10.1016/S0040-4039(00)99867-8]
- Bhatia, N. et al., J. Indian Chem. Soc., 1985, 62, 75- 76 (Excelsin, cmr)
- Lumonadio, L. et al., Phytochemistry, 1985, 24, 2387- 2389 (Hannoa klaineana constits) [https://doi.org/10.1016/S0031-9422(00)83047-2]
- Niimi, Y. et al., Bull. Chem. Soc. Jpn., 1986, 59, 1638- 1640 (Shinjulactone N) [https://doi.org/10.1246/bcsj.59.1638]
- O'Neill, M.F. et al., J. Ethnopharmacol., 1988, 22, 183- 190 (Simarouba amara constits) [https://doi.org/10.1016/0378-8741(88)90126-2]
- Hamburger, M.O. et al., Planta Med., 1988, 54, 352- 355 (pmr, cmr) [https://doi.org/10.1055/s-2006-962456]
- Gross, R.S. et al., JACS, 1990, 112, 9436- 9437; 1993, 115, 6078 - 6093 (Chaparrinone,synth) [https://doi.org/10.1021/ja00181a079]
- Chaudhuri, S.K. et al., Phytochemistry, 1992, 31, 3961- 3964 (Castelosides A,B) [https://doi.org/10.1016/S0031-9422(00)97563-0]
- Fleck, T.J. et al., Tet. Lett., 1992, 33, 1813- 1816 (Glaucarubolone, Holacanthone, synth) [https://doi.org/10.1016/S0040-4039(00)74149-9]
- Diakanamwa, C. et al., J. Nat. Prod., 1993, 56, 1817- 1820 (14-Hydroxychaparrenone) [https://doi.org/10.1021/np50100a024]
- Grieco, P.A. et al., JACS, 1993, 115, 6078- 6093 (Glaucarubol, synth) [https://doi.org/10.1021/ja00067a025]
- Grieco, P.A. et al., Phytochemistry, 1994, 37, 1451- 1454 (Peninsularinone, Glaucarubolone,Glaucarubinone, struct) [https://doi.org/10.1016/S0031-9422(00)90431-X]
- Dou, J. et al., J. Nat. Prod., 1996, 59, 73- 76 (Castela texana constit) [https://doi.org/10.1021/np960013j]
- Kubota, K. et al., J. Nat. Prod., 1996, 59, 683- 686 (Ailantinol B) [https://doi.org/10.1021/np960427c]
- Rodriguez Fo, E. et al., Phytochemistry, 1996, 43, 857- 862 (Glaucarubolone, pmr, cmr)
- Vieira, I.J.C. et al., Fitoterapia, 1998, 69, 88- 90 (Glaucarubol, Glaucarubolone, pmr, cmr)
- Francois, G. et al., Int. J. Parasitol., 1998, 28, 635- 640 (activity) [https://doi.org/10.1016/S0020-7519(98)00008-3]
- Ozeki, A. et al., J. Nat. Prod., 1998, 61, 776- 780 (Glaucarubolone, Glaucarubol, activity) [https://doi.org/10.1021/np980023f]
- Dayan, F.E. et al., Pestic. Biochem. Physiol., 1999, 65, 15- 24 (activity) [https://doi.org/10.1006/pest.1999.2432]
- Grieco, P.A. et al., Phytochemistry, 1999, 50, 637- 645 (Castela polyandra constits, cryst struct) [https://doi.org/10.1016/S0031-9422(98)00589-5]
- Kanchanapoom, T. et al., Phytochemistry, 2001, 57, 1205- 1208 (Iandonoside A, struct) [https://doi.org/10.1016/S0031-9422(01)00235-7]
- Joshi, B.C. et al., Phytochemistry, 2003, 62, 579- 584 (3,4-Dihydroexcelsin, struct) [https://doi.org/10.1016/S0031-9422(02)00493-4]
- Jacobs, H. et al., Biochem. Syst. Ecol., 2007, 35, 42- 44 (Castela macrophylla constits) [https://doi.org/10.1016/j.bse.2006.08.005]
- Beutler, J.A. et al., J. Nat. Prod., 2009, 72, 503- 506 (Holacanthone, activity) [https://doi.org/10.1021/np800732n]
- Usami, Y. et al., J. Nat. Prod., 2010, 73, 1553- 1558 (2'R-Acetylglaucarubinone) [https://doi.org/10.1021/np100406d]
- Wang, Y. et al., Bioorg. Med. Chem. Lett., 2013, 23, 654- 657 (Altissinols A,B) [https://doi.org/10.1016/j.bmcl.2012.11.116]
- Meng, D. et al., Fitoterapia, 2014, 92, 105- 110 (Δ4-14-Hydroxyglaucarubol, cryst struct) [https://doi.org/10.1016/j.fitote.2013.10.009]
- Sax's Dangerous Properties of Industrial Materials, 11th edn., J. Wiley, 2004, GEW700
Anticancer Citations
- Ham, A. et al., JACS, 1954, 76, 6066- 6068 (Glaucarubin, isol, ir) [https://doi.org/10.1021/ja01652a060]
- US Pat., 1958, 2 864 745 (Glaucarubin, amoebicidal activity)
- Polonsky, J. et al., Bull. Soc. Chim. Fr., 1964, 1818- 1826, 1827 - 1835; 1965, 2793 - 2799 (Glaucarubin, Glaucarubolone, pmr, struct)
- Kartha, G. et al., JACS, 1964, 86, 3630- 3634 (Glaucarubin, cryst struct) [https://doi.org/10.1021/ja01072a008]
- Polonsky, J. et al., Tet. Lett., 1964, 5, 3983- 3990 (Ailanthone, Ailanthinone) [https://doi.org/10.1016/S0040-4039(01)89352-7]
- Casinovi, G.G. et al., Tet. Lett., 1964, 5, 3991- 3997 (Ailanthinone, struct) [https://doi.org/10.1016/S0040-4039(01)89353-9]
- Polonsky, J. et al., Bull. Soc. Chim. Fr., 1965, 2793- 2799 (Chaparrinone)
- De Mayo, P. et al., Can. J. Chem., 1965, 43, 2996- 3007, 3008 - 3017 (Chaparrin)
- Nyburg, S.C. et al., Chem. Comm., 1965, 203- 204 (Glaucarubin, abs config)
- Moron, J. et al., Tet. Lett., 1965, 9, 385- 390 (Simaroubaceae terpenoids, biosynth) [https://doi.org/10.1016/S0040-4039(01)98767-2]
- Fourrey, J.L. et al., Org. Mass Spectrom., 1968, 1, 819- 833 (ms)
- Gaudemer, A. et al., Phytochemistry, 1968, 4, 149- 153 (Glaucarubolone, Glaucarubinone,struct) [https://doi.org/10.1016/S0031-9422(00)86157-9]
- Stöcklin, W. et al., Phytochemistry, 1969, 8, 1565- 1569 (Glaucarubol, struct) [https://doi.org/10.1016/S0031-9422(00)85931-2]
- Moron, J. et al., Phytochemistry, 1971, 10, 585- 592 (Glaucarubolone, Glaucarubinone,biosynth) [https://doi.org/10.1016/S0031-9422(00)94702-2]
- Kupchan, S.M. et al., JOC, 1975, 40, 654- 656 (Ailanthinone, Dehydroailanthinone, 2'S-Acetylglaucarubinone, struct) [https://doi.org/10.1021/jo00893a024]
- Polonsky, J. et al., JOC, 1975, 40, 2499- 2504 (cmr) [https://doi.org/10.1021/jo00905a017]
- Gottlieb, H.E. et al., JOC, 1975, 40, 2499- 2504 (Ailanthinone, Glaucarubinone, cmr)
- Kupchan, S.M. et al., J. Med. Chem., 1976, 19, 1130- 1133 (Glaucarubolone esters, sar) [https://doi.org/10.1021/jm00231a009]
- Ogura, M. et al., J. Nat. Prod., 1977, 40, 579- 584 (2'-Acetylglaucarubin)
- Polonsky, J. et al., Experientia, 1978, 34, 1122- 1123 (13,18-Dehydroglaucarubinone)
- Polonsky, J. et al., C. R. Seances Acad. Sci., Ser. C, 1979, 288, 269- 271 (Castelanone,struct)
- Khan, S.A. et al., Indian J. Chem., Sect. B, 1980, 19, 183- 184 (Excelsin, struct)
- Khan, S.A. et al., Phytochemistry, 1980, 19, 2484- 2485 (13,18-Dehydroexcelsin) [https://doi.org/10.1016/S0031-9422(00)91062-8]
- Tri, M.V. et al., J. Nat. Prod., 1981, 44, 279- 284 (Soularubinone, struct, activity)
- Naora, H. et al., Chem. Pharm. Bull., 1983, 56, 3694- 3698 (Shinjulactone A, Ailanthone,cryst struct)
- Handa, S.S. et al., J. Nat. Prod., 1983, 46, 359- 364 (Holacanthone, struct, activity) [https://doi.org/10.1021/np50027a011]
- Ishibashi, M. et al., Bull. Chem. Soc. Jpn., 1984, 57, 2484- 2489, 2496-2501 (Shinjulactone D, Shinjuglycosides)
- Waterman, P.G. et al., Planta Med., 1984, 50, 261- 263 (Odyendyea gabonensis constits) [https://doi.org/10.1055/s-2007-969694]
- Bhatnagar, S. et al., Tet. Lett., 1984, 25, 299- 302 (Simarouba glauca constits, cryst struct) [https://doi.org/10.1016/S0040-4039(00)99867-8]
- Bhatia, N. et al., J. Indian Chem. Soc., 1985, 62, 75- 76 (Excelsin, cmr)
- Lumonadio, L. et al., Phytochemistry, 1985, 24, 2387- 2389 (Hannoa klaineana constits) [https://doi.org/10.1016/S0031-9422(00)83047-2]
- Niimi, Y. et al., Bull. Chem. Soc. Jpn., 1986, 59, 1638- 1640 (Shinjulactone N) [https://doi.org/10.1246/bcsj.59.1638]
- O'Neill, M.F. et al., J. Ethnopharmacol., 1988, 22, 183- 190 (Simarouba amara constits) [https://doi.org/10.1016/0378-8741(88)90126-2]
- Hamburger, M.O. et al., Planta Med., 1988, 54, 352- 355 (pmr, cmr) [https://doi.org/10.1055/s-2006-962456]
- Gross, R.S. et al., JACS, 1990, 112, 9436- 9437; 1993, 115, 6078 - 6093 (Chaparrinone,synth) [https://doi.org/10.1021/ja00181a079]
- Chaudhuri, S.K. et al., Phytochemistry, 1992, 31, 3961- 3964 (Castelosides A,B) [https://doi.org/10.1016/S0031-9422(00)97563-0]
- Fleck, T.J. et al., Tet. Lett., 1992, 33, 1813- 1816 (Glaucarubolone, Holacanthone, synth) [https://doi.org/10.1016/S0040-4039(00)74149-9]
- Diakanamwa, C. et al., J. Nat. Prod., 1993, 56, 1817- 1820 (14-Hydroxychaparrenone) [https://doi.org/10.1021/np50100a024]
- Grieco, P.A. et al., JACS, 1993, 115, 6078- 6093 (Glaucarubol, synth) [https://doi.org/10.1021/ja00067a025]
- Grieco, P.A. et al., Phytochemistry, 1994, 37, 1451- 1454 (Peninsularinone, Glaucarubolone,Glaucarubinone, struct) [https://doi.org/10.1016/S0031-9422(00)90431-X]
- Dou, J. et al., J. Nat. Prod., 1996, 59, 73- 76 (Castela texana constit) [https://doi.org/10.1021/np960013j]
- Kubota, K. et al., J. Nat. Prod., 1996, 59, 683- 686 (Ailantinol B) [https://doi.org/10.1021/np960427c]
- Rodriguez Fo, E. et al., Phytochemistry, 1996, 43, 857- 862 (Glaucarubolone, pmr, cmr)
- Vieira, I.J.C. et al., Fitoterapia, 1998, 69, 88- 90 (Glaucarubol, Glaucarubolone, pmr, cmr)
- Francois, G. et al., Int. J. Parasitol., 1998, 28, 635- 640 (activity) [https://doi.org/10.1016/S0020-7519(98)00008-3]
- Ozeki, A. et al., J. Nat. Prod., 1998, 61, 776- 780 (Glaucarubolone, Glaucarubol, activity) [https://doi.org/10.1021/np980023f]
- Dayan, F.E. et al., Pestic. Biochem. Physiol., 1999, 65, 15- 24 (activity) [https://doi.org/10.1006/pest.1999.2432]
- Grieco, P.A. et al., Phytochemistry, 1999, 50, 637- 645 (Castela polyandra constits, cryst struct) [https://doi.org/10.1016/S0031-9422(98)00589-5]
- Kanchanapoom, T. et al., Phytochemistry, 2001, 57, 1205- 1208 (Iandonoside A, struct) [https://doi.org/10.1016/S0031-9422(01)00235-7]
- Joshi, B.C. et al., Phytochemistry, 2003, 62, 579- 584 (3,4-Dihydroexcelsin, struct) [https://doi.org/10.1016/S0031-9422(02)00493-4]
- Jacobs, H. et al., Biochem. Syst. Ecol., 2007, 35, 42- 44 (Castela macrophylla constits) [https://doi.org/10.1016/j.bse.2006.08.005]
- Beutler, J.A. et al., J. Nat. Prod., 2009, 72, 503- 506 (Holacanthone, activity) [https://doi.org/10.1021/np800732n]
- Usami, Y. et al., J. Nat. Prod., 2010, 73, 1553- 1558 (2'R-Acetylglaucarubinone) [https://doi.org/10.1021/np100406d]
- Wang, Y. et al., Bioorg. Med. Chem. Lett., 2013, 23, 654- 657 (Altissinols A,B) [https://doi.org/10.1016/j.bmcl.2012.11.116]
- Meng, D. et al., Fitoterapia, 2014, 92, 105- 110 (Δ4-14-Hydroxyglaucarubol, cryst struct) [https://doi.org/10.1016/j.fitote.2013.10.009]
- Sax's Dangerous Properties of Industrial Materials, 11th edn., J. Wiley, 2004, GEW700