| PI | DEPARTMENT | CENTER | PROJECT |
| Changhui Pak | Biochemistry & Molecular Biology | M2M | Exploring Venom Neuropeptide Mimics as Precision Modulators of Human Neuronal Signaling |
| PI | DEPARTMENT | CENTER | PROJECT |
| Xian Du | Mechanical & Industrial Engineering | CPHM/CBD | 3D Light Printing for Transdermal Drug Delivery Patches and Microneedles with Integrated Real-Time Monitoring |
| Stephanie Padilla | Biology | CPHM | The mechanism underlying menopausal hot flushes: thermosensory input to the neuroendocrine reproductive axis. |
| Elena Vazey | Biology | M2M | Exploring platelet factors as a therapeutic target for alcohol use disorder |
| Wouter Hoogkamer | Kinesiology | CPHM | Novel Technologies to Reduce Gait Asymmetries in Stroke Patients: Proof of Concept |
| Joyita Dutta | Biomedical Engineering | CPHM | Advancing AI-Assisted Radiopharmaceutical Therapy: A UMass Inter-Campus Strategic Partnership |
| Chase Cornelison | Biomedical Engineering | M2M | Development and validation of a circadian reporter system in astrocytes |
| Anna Green | Information & Computer Science | M2M | Machine learning to redesign antibiotics with boosted efficiency against M. tuberculosis |
| David Moorman | Psychological and Brain Sciences | M2M | Circadian regulation of neural circuits regulating cocaine seeking |
| Mark Miller | Kinesiology | CPHM/M2M | Iron replacement to improve cellular and molecular contractile function in patients with chronic kidney disease |
| John Sirard | Kinesiology | CPHM | Identifying Resistance Training Exercise using Wearable Accelerometers |
| Igor Kaltashov | Chemistry | M2M | Transient molecular signals in hemo- and lymphodynamics in health and disease |
| Joseph Bergan | Psychological and Brain Sciences | M2M | The impact of hunger on neural encoding of social behavior |
| Kristen DeAngelis | Microbiology | M2M | Lignin to bioplastics: defining and developing new technologies towards a microbial molecular sieve for the valorization of lignin |
| Joyita Dutta | Biomedical Engineering | CPHM | Advancing AI-Assisted Radiopharmaceutical Therapy: A UMass Inter-Campus Strategic Partnership |
| PI | DEPARTMENT | CENTER | PROJECT |
| Jeanne Hardy | Chemistry | M2M/CBD | A two-pronged approach to develop Inhibitores of Chikungunya virus infection |
| Alice Cheung | Biochemistry and Molecular Biology | M2M | Towards developing a sensor for environmental stresses at the plant cell surface |
| Jeremy Gummeson | Electrical and Computer Engineering | CPHM | Establishing a Model for Human Metabolic Rate Estimation Using Harvested Thermoelectric Power |
| ChangHui Pak | Biochemistry and Molecular Biology | M2M | Innovation of Human Cerebellar Organoids for Stem Cell Therapy in Cerebellar Degenerative Disorders |
| Thomas Maresca | Biology | M2M | REVISED - Axonal transport: function versus dementia-related dysfunction. |
| Sarah Roelker | Kinesiology | CPHM | Investigating Physical Activity Effects on Pregnancy Musculoskeletal Health |
| Li-Jun Ma | Biochemistry & Molecular Biology | M2M | How could one endophytic fungal strain promote the growth of both monocot |
| Seth Donahue | Biomedical Engineering | CPHM | Bioinspired shoes for mitigating osteoarthritic knee pain |
| Margaret Straton | Biochemistry and Molecular Biology | M2M | Understanding the molecular mechanism of Ca2+/calmodulin-dependent protein kinase II (CaMKII) degradation by the ubiquitin proteasome system (UPS) |
| Andrew Stephens | Biology | M2M | Analyzing the role of transcription in nuclear mechanics, structure, and function |
| Jesse Mager | VASCI | M2M | A novel protocol to enhance IVF success |
| Courtney Babbit | Chemical Engineering | M2M | This collaborative project from the Babbitt and Peyton labs will study how astrocytes from humans and primates respond to injury. |
| Kathleen Arcaro | Veterinary & Animal Sciences | M2M | Effects of Maternal Diet and Breastfeeding Practices on the Infant Gut Microbiome |
| Rebecca Spencer | PBS | CPHM | Neuroscience of sleep and aging |
| Alexander Suvorov | Environmental Health Sciences | CPHM | Aging Mechanisms |
| Phuc Nguyen | Computer Science | CPHM | A Novel Bio-Inspired Exfoliation Platform for Assistive Robots |
| Leonid Pobezinsky | VASci | M2M | Discovering origins and traits of tumor supper-killer-T cells. |
| ChangHui Pak | Biochemistry & Molecular Biology | M2M | Generation of isogenic revertant controls from patient derived iPSCs with CASK deficiency |
| PI | DEPARTMENT | CENTER | PROJECT |
| Kathleen Arcaro | VASci | M2M | Chronic Inflammation and DNA Methylation in Breast Cells |
| Alissa Rothchild | VASci | M2M | Chemical detection of Mycobacterium tuberculosis replication within infected host cells |
| Rafael Fissore | VASci | M2M | Study of sperm-specific Phospholipases C in reproduction |
| Lili He | Food Science | CPHM | Quantification of bacterial contamination levels on surfaces |
| Katherine Boyer | Kinesiology | CPHM | Feasibility of mHealth sensor platform to identify TKA candidate biomechanical phenotypes |
| Yubing Sun | Mechanical & Industrial Engineering | M2M/CPHM | Understanding and controlling stem cell differentiation through a “RECODE” mechanism |
| Simos Gerasimidis | Civil & Environmental Engineering | CPHM | 3d printing of metal auxetic lattices in the mesoscale |
| Rachel Walker | Nursing | CPHM | metal lattice prisms using the EOS |
| Megan Huber | Mechanical & Industrial Engineering | CPHM | Human-Centered Robotics |
| Madalina Fiterau | CICS | CPHM | 4Thought - A diagnostics startup focused on the early detection of Alzheimer's using AI and ML |
| Joohyun Chung | Nursing | CPHM | Conversational AI (artificial intelligence) for early detection of subtle cognitive decline. |
| Edward Debold | Kinesiology | M2M | Characterizing the load-dependence of molecular motor to understand cellular motility |
| Barbara Osborne | VASci | CBD |
| PI | DEPARTMENT | CENTER | PROJECT |
| Sloan Siegrist | Microbiology | M2M | Screen for small molecules that permeabilize the mycomembrane. |
| Ana Caicedo | Biology | M2M | Employing wild tomatoes to battle fusarium wilts of tomato |
| Jane Kent | Kinesiology | CPHM | A Multi-Scalar Approach to Linking Skeletal Muscle Bioenergetics and Daily Energy Metabolism in Humans |
| T. Leo Liu | Mechanical & Industrial Engineering | CPHM | Mechanically resilient super-repellent surfaces |
| T. Leo Liu | Deformable Super-repellent Interfaces with High Mechanical Resilience | ||
| Yasu Morita | Microbiology | M2M | Nanosponge emulsification improves the efficacy of phytochemicals and antimycobacterial drugs, especially against biofilm growth |
| Heather Richardson | Psychological & Brain Sciences | M2M | Antimycobacterial drugs, especially against biofilm growth. |
| ChangHui Pak | Biochemistry & Molecular Biology | M2M | Develop a human induced pluripotent stem (hiPS) cell model of TBCK Syndrome |
| Jinglei Ping | Mechanical & Industrial Engineering | CPHM | Implantable Blood-Flow Sensor Based on Monolayer-Graphene |
| Sunghoon (Ivan) Lee | Biomedical Engineering | CPHM | Unobtrusively Estimating Upper-Limb Impairment Level in Stroke Survivors using a Single Wearable Inertial Sensor |
| S. Thai Thayumanavan | Biomedical Engineering | CBD/M2M | Novel antibody-directed synthetic lethality strategy for targeted delivery of chemotherapeutic molecules to specific sub-types of breast cancer. |
| Carlos Gradil | VASci | M2M | 3Daughters |
| PI | DEPARTMENT | CENTER | PROJECT |
| Govind Srimathveeravalli | Mechanical & Industrial Engineering | CBD/M2M | Humanized breast model in mice using intraductal irreversible electroporation |
| Kathleen Arcaro | Veterinary & Animal Sciences | M2M | Validation and establishment of a breast milk spot card for nation-wide screening: assessing antibodies and cytokines in the milk of women diagnosed with COVID-19 and women who received a COVID-19 vaccine. |
| Jinglei Ping | Mechanical & Industrial Engineering | CPHM | The platform technology based on graphene bioelectronics for multiplex nucleic-acid analysis |
| Karen Giuliano | Nursing | CPHM | Flow Accuracy of IV Infusion Pumps Outside Patient Rooms During COVID-19. |
| Barbara Osborne | VASci | CBD | Development of a SARS-CoV2 neutralization assay. |
| PI | DEPARTMENT | CENTER | PROJECT |
| Caitlyn Butler | Civil & Environmental Engineering | CBD | Wastewater surveillance of SARS-CoV2 at UMass and in Amherst. |
| Gwenael Layec | CPHM | ||
| Igor Kaltashov | Chemistry | M2M | Identifying inhibitors of the SARS-CoV-2 spike protein (S-protein) association with its receptor, human membrane protease ACE2. |
| Mandy Muller | Microbiology | M2M | SARS-CoV2 nsp1: a master regulator of RNA stability. |
| Andrew Lover | Biostatistics & Epidemiology | M2M | Community-level Serological Surveys to Assess SARS-CoV2 Antibody Prevalence in Massachusetts using Self-Sampling. |
| Sunghoon (Ivan) Lee | Biomedical Engineering | CPHM | Pre-emptive Low-cost Wearable Solution to Discourage Face Touching. |
| Rachid Skouta | Chemistry | M2M | In Vivo Ferroptosis Inducers for Triple Negative Breast Cancer |
| Jun Yao | Electrical & Computer Engineering | CPHM | Integrated bioelectronic sensor arrays - a highly sensitive wearable sensors from proof-of-concept device to standardized scalable integration, which will be the key to biomedical implementation. |
| Rachid Skouta | Chemistry | CBD | In Vivo Ferroptosis Inducers for Triple Negative Breast Cancer. |
| PI | DEPARTMENT | CENTER | PROJECT |
| Simos Gerasimidis | Civil & Environmental Engineering | CPHM | |
| Mingxu You | Chemistry | M2M | Integrated bioelectronic sensor arrays - a highly sensitive wearable sensors from proof-of-concept device to standardized scalable integration, which will be the key to biomedical implementation. |
| Alejandro Heuck | Biochemistry & Molecular Biology | M2M | Combating Antibiotic Resistant Bacteria (CARB-X) |
| Maria Santore | Polymer Science & Engineering | M2M | Dynamic Touch-based Bacteria-Device Two-Way Communication |
| PI | DEPARTMENT | CENTER | PROJECT |
| Barry Goodell | Microbiology | M2M | Redox Chemistries Involved in Carbon Cycling and Xenobiotic Degradation by Marine Mollusks |
| Rolf Karlstrom | Biology | M2M | The Virtual Zebrafish Brain |
| Peter Chien | Biochemistry & Molecular Biology | M2M | Nonparametric Bayesian Methods for Single-cell DNA Sequence Analysis to Map the Mutational Landscape of Chaperone-Mediated Protein Folding |
| Patricia Wadsworth | M2M | Structure and function of a minimal mitotic spindle. | |
| David Moorman | Psychological & Brain Sciences | M2M | Develop a new line of research investigating the role of the orexin/hypocretin (ORX) system in alcohol use and addiction. |
| Ashish Kulkarni | Chemical Engineering | CBD | A nanoscale platform technology for early monitoring of immunotherapy response. |
| S. Thai Thayumanavan | Biomedical Engineering | CBD | Nanogels for Liver-Targeted Therapeutic Delivery |
| Larry Schwartz | Molecular & Cellular Biology | M2M | Develop in vitro assays for small molecule high-throughput screens to identify inhibitors of Acheron:BAD binding that might be developed into novel therapeutics to either kill TNBC outright or potentially sensitize them to conventional therapeutics. |
| Lisa Minter | Veterinary & Animal Sciences | M2M | Establish and validate a pre-clinical model of human disease, within the IALS Animal Model Core. |
| Dong Wang | Biochemistry & Molecular Biology | M2M | Research group studying the nitrogen-fixing symbiosis between a class of bacteria (rhizobia) and a group of plants (legumes). |
| PI | DEPARTMENT | CENTER | PROJECT |
| Mingxu You | Chemistry | M2M | Novel DNA-based molecular probes to quantify and visualize the spatiotemporal distribution of intercellular forces |
| Agnes Lecreuse | Psychological & Brain Sciences | M2M | Finding a new, safe, and effective hormone therapy for women with menopausal symptoms. |
| Courtney Babbitt | Biology | M2M | Basic Cancer Research in Cancer Health Disparities |
| PI | DEPARTMENT | CENTER | PROJECT |
| Katherine Boyer | Kinesiology | CPHM | Misfit Shine Detection of Change in Physical Activity: Evidence and Translation for a new Clinical Outcome Tool. |
| Michelle Farkas | Chemistry | CBD/M2M | Harnessing Macrophages as Cell-Based Delivery Agents for Cancer Imaging and Treatment. |
| Jeanne Hardy | Chemistry | M2M | Furoxan-based Caspase-6 Inhibitors for Treatment of Neurodegeneration. |
| Karen Kalmakis | College of Nursing | CPHM | Real-time continuous cortisol monitoring: An innovation for stress self-management. |
| Vince Rotello | Chemistry | CBD/M2M | shRNA Therapeutics for Non-Hodgkin's Lymphoma. |
| Yubing Sun | Mechanical & Industrial Engineering | M2M/CPHM | Self-powered integrated blood separation and SERS-based immunoassay (SIBSI) device for point of care analysis of pancreatic cancer biomarkers. |
| Jim Watkins | Polymer Science & Engineering | CPHM | Autonomous Sensor Platforms for In-Home and On-Body Health Monitoring. |