
Processing and isolation of bioactive food components, emulsions, and powders
Equipment

Pilot Plant Agglomeration System
This GEA system allows for spray drying and agglomeration to produce powders from food and bioactive delivery systems.

UHT/HTST Pasteurization Unit
The Microthermics system allows for both High Temperature Short Time and UltraHigh Temperature pasteurization and aseptic filling.

Preparative HPLC with Mass Spectroscopy
The Shimadzu system can be used for preparative scale isolation and identification of bioactive using standard HPLC techniques.

Freeze Drying System
A small scale lyophilization system for food grade components.

Laser Diffraction Particle Size Analyzer
Conducts analysis of physical characteristics of powders.

Size Exclusion Chromatography
HPLC technique to characterize biopolymers.

Nano Crystallization Units
Homogenization technique that can be used to produce nanocrystals for food and pharma applications.

Colonic Fermenter
A model colonic microbial model system that can be used to test the metabolic fates of nutrients and pharmaceuticals.

Supercritical Fluid System
A carbon dioxide method for the clean isolation of bioactive compounds from biological materials.

Gas Absorption Analyzer
Fully automated, high vacuum, manometric gas sorption analyzer capable of analyzing surface area, pore size distribution, pore volume and isothermal heats of adsorption using a variety of coolants and adsorbates for a wide variety of sample types.

Reverse Osmosis Pilot Plant Ultrafiltration Unit
A technique for the removal of water and small molecular weight compounds from aqueous systems.

Agitating retort
A pilot scale retort for sterilization of flexible pouches.

Constant Systems CF Range Cell Disruptor
The CF cell disruptor in the core is a “French press” type system to lyse cells and extract expressed proteins. Once a sample is drawn into our high pressure cylinder, pressure is built until it reaches the value set by the user. Then a piston forces the sample through a fixed orifice at high velocity before it impacts on a cooled heat exchange surface, and then flows through an outlet for collection.

ÄKTA Flux 6
ÄKTA flux is a versatile cross flow filtration system for sample concentration and diafiltration as well as cell harvest and clarification.
- Low working and hold-up volumes to support a wide range of concentration factors
- Automated end-point control and data logging
- Flexible handling of both hollow fiber cartridges and cassettes
- Versatile design enables use in both ultra- and microfiltration applications
- Easy-to-use operator interface
The ÄKTA flux system allows effortless filtrations using cassettes and hollow fiber filter cartridges. It is available in two versions: ÄKTA flux s for research and filter screenings, and ÄKTA flux 6 for process development and scale-up experiments.
The ÄKTA flux filtration system is well-suited for use in protein purification workflows as a complement to the ÄKTA chromatography systems.
Location
127 Chenoweth Laboratory
University of Massachusetts Amherst
100 Holdsworth Way
Amherst, MA 01003