Human Magnetic Resonance Center


Human Magnetic Resonance Center

state-of-the-art non-invasive whole body imaging

Located on the 2nd floor in the Life Science Laboratories the Human Magnetic Resonance Center (hMRC) provides state-of-the-art, non-invasive neuroimaging, whole body imaging, and spectroscopy technologies for academic and industry-based research in central and western Massachusetts. This is the only research-dedicated 3T MRI/MRS system in western Massachusetts. This system is ideal for investigating questions regarding normal and abnormal changes in human brain and whole body structure and function across the lifespan.

Center email: hmrc@umass.edu

Remote video URL
Watch Core Facilities Seminar: Human Magnetic Resonance Center (hMRC) on YouTube.
Tuesday, May 4, 2021

Human Magnetic Resonance Center (hMRC)

2:00 pm

Rajakumar Nagarajan, MR Physicist, hMRC

Guest Speaker
Gwenael Layec, Assistant Professor, Kinesiology Department and IALS–“Investigation of Muscle Function by MR Spectroscopy/Imaging”

Siemens 3T Skyra Scanner

Siemens 3T Skyra Scanner

Siemens 3T (123 MHz) Skyra is a 70-cm bore MRI/MRS scanner for acquisition of BOLD, Diffusion, and MR spectroscopy data. The scanner uses state-of-the-art technology for fast and efficient collection of:

  • structural neuroimaging (white and gray matter and CSF morphology and diffusion tractography),
  • functional neuroimaging (resting state and task-based fMRI),
  • multi-nuclear spectroscopy (1H, 31P and 13C)
  • MR elastography
  • structural imaging of bone and tissue
Neuroimaging-four views of brain scan

Functional Neuroimaging

Noninvasive imaging that measures brain activity and function during resting state and task-based imaging (fMRI) by detecting dynamic physiological processes in real time associated with blood flow and the blood oxygen levels in response to neural activation and consumption, this is referred to as BOLD or Blood Oxygen Level Dependent Imaging. This is used to investigate neurotypical brain connectivity and regional function across the lifespan and to understand brain dysfunction and neuroplasticity. 

Magnetic resonance spectroscopy stack

Spectroscopy

Magnetic resonance spectroscopy (MRS) is a noninvasive data collection technique that is ideal for measuring biochemical content and metabolism of tissues in the body. This method allows us to gather metabolic information, which is unique and independent, but complementary to the anatomic information obtained with other magnetic resonance imaging (MRI) techniques in various pathology. MRS is able to display data in various ways, including chemical composition and measurement of the spatial distribution of metabolite concentrations.

Aphasia sag left to right

Structural Brain Imaging

Static imaging of the white and gray matter and CSF of the brain, as well as bone and tissue, are used to examine typical structural morphology and connectivity, as well as atypical structure, neuroplasticity, and neurodegeneration.

Musculoskeletal & Whole Body MRI

Musculoskeletal & Whole Body MRI

Demonstrates various aspects of muscle, organ, bone, joint, soft tissue and nerve structure and function. High resolution images can be generated in which the following details can be demonstrated: fat, muscle, tendons, ligaments, and fluid as well as vasculature and nerve systems. These can be used to quantify various data such as fat quantification, edema, pathology and structural damage or degeneration.

Equipment

Siemens 3T Skyra Scanner

Siemens 3T Skyra Scanner

Siemens 3T (123 MHz) Skyra is a 70-cm bore MRI/MRS scanner for acquisition of BOLD, Diffusion, and MR spectroscopy data. The scanner uses state-of-the-art technology for fast and efficient collection of:

  • structural neuroimaging (white and gray matter and CSF morphology and diffusion tractography),
  • functional neuroimaging (resting state and task-based fMRI),
  • multi-nuclear spectroscopy (1H, 31P and 13C)
  • MR elastography
  • structural imaging of bone and tissue,

The Skyra provides a wide bore and short length, making it ideal for scanning certain populations, e.g., children and obese persons, who may otherwise feel claustrophobic in a typical 60mm bore.

Additional Equipment

Additional Equipment

  • The hMRC is equipped with 3 head coils (20, 32, and 64 channel), and a full array of body, foot/ankle, knee, and breast coils, and a docking exam table.
  • A variety of MR compatible peripheral equipment is available, such as a 32” high resolution BOLD screen, a 128-channel EEG system, an eyetracking system, an active noise canceling microphone/headphone system, a system for MR elastography, an ergometer, and an array of button box, grip force, and joystick devices for acquiring experimental responses.
  • The hMRC has a complete mock scanner system, including participant interfaces, and is particularly well suited for training participants to stay still in the scanner.
  • Double tuned 1H-31P and 1H-13C surface and volume coils.
hMRC Scan

Ancillary Equipment

  • BOLD screen: Cambridge Research Systems (http://www.crsltd.com) LCD monitor, 32", 1920x1080 resolution, 120Hz refresh rate
  • Button response unit: Current Design (http://www.curdes.com/), package 932, 4 buttons on both hands
  • Audio system: Optoacoustic, Optoactive ANC headphone, FOMRI-III microphone
  • 128-channel EEG system: Brain Vision, (http://brainvision.com/products/), BrainAmp
  • Eyetracking system: SR Research, EyeLink 1000 Plus system
  • Ergometer

Staff

  • Location

    S230 Life Science Laboratories
    University of Massachusetts Amherst
    240 Thatcher Road
    Amherst, MA 01003

    hmrc@umass.edu