Contact
Email
Location
Room 252, Chenoweth Laboratory

Field of Study

Functional foods (bioactive food components), biologically beneficial effects of conjugated linoleic acid, obesity, and environmental contaminants and development of obesity and type 2 diabetes

Research

My current research interests can be divided into two categories; first, food bioactives for prevention of obesity and aging and secondly, investigating environmental contaminants and development of obesity and type 2 diabetes.

A. Food Bioactives for Prevention of Obesity and Aging

This research interest started as I have worked on Conjugated Linoleic Acid (CLA). CLA was originally identified unexpectedly as an anti-cancer principal from ground beef in 1987. Since then, CLA has shown other biologically beneficial activities, including reducing body fat. In addition, I have expanded my research focus for many other food bioactives for obesity prevention. For this, I have used multiple experimental models, such as rodents, Caenorhabditis elegans, Drosophila, as well as many types of mammalian tissue culture models. Among them, C. elegans is also used for identifying potential food bioactives for aging study as this model has many benefits for research for aging, including a short life-span.

B. Environmental Contaminants and Development of Obesity and Type 2 Diabetes

In line with above mentioned research interest on obesity, it is important to note that current epidemic of obesity and related diseases cannot be explained completely by considering changes in societal, behavioral, or dietary habits of individuals. Recently, there is an emerging body of evidence indicating that exposure to persistent organic pollutants, including insecticides, were positively correlated with e­­xcessive weight gain and altered glucose homeostasis. However, the detailed molecular mechanism regarding how these environmental chemicals perturb metabolism and ultimately contribute to the development of obesity and other related diseases have yet to be elucidated fully. Thus my group is investigating the role of insecticides on development of obesity and type 2 diabetes.

Teaching

FS150 Science of Food (Gen. Ed. BS)
FS 270   Biology of Food in Human Health
FS 797E Bioactive Food Components
FS 797G Functional Foods
Honors 391D Advance Honors Seminar (1 credit): Foods that prevent disease

Awards

2017 & 2018 Clarivate Highly Cited Researcher (Agriculture)

2015 Faculty Convocation Award, University of Massachusetts

2015 Timothy Mounts Award, American Oil Chemists’ Society

2014 Thomson Reuters Highly Cited Researcher (Agriculture)

2014 ASN's Korean Nutrition Society Award

2009 Armstrong Fund for Science Award at UMass

ILSI 2007 Future Leader Award

Outstanding Division Volunteer Award 2007, 2008 & 2011 IFT Food Chemistry Division

American Oil Chemists Society 2003 Young Scientist Research Award

Publications

Refereed Journals

Since joining the University of Massachusetts

Under-Review

1. Y. Yue, P. Shen, A. L. Chang, W. Qi, K.-H. Kim, and Y. Parktrans-Trismethoxy Resveratrol Decreased Fat Accumulation Dependent on fat-6 and fat-7 in Caenorhabditis elegansFood Func. (submitted).

2. W. Qi, J. M. Clark, and Y. Park, Ivermectin Inhibits Differentiation of 3T3-L1 Preadipocytes, Food Chem. Tox. (submitted).

3. R. Farias-Pereira, E. Kim, and Y. Park, Cafestol increases fat oxidation and energy expenditure in Caenorhabditis elegans via DAF-12-dependent pathway, Food Chem. (submitted).

Accepted for publication

4. Y. Peng, Q. Sun, and Y. Park, The Bioactive Effects of Chicoric Acid as a Functional Food Ingredient, J. Med Food

5. Y. Peng, Q. Sun, R. Gao, and Y. Park, Chicoric Acid Extends the Lifespan of Caenorhabditis elegans: The Involvement of AAK-2 and SKN-1, J. Ag. Food Chem.

6. P. B. Chen, J. H. Kim, L. Young, J. M. Clark, and Y. Park, Epigallocatechin gallate (EGCG) Alters Body Fat and Lean Mass Through Sex-Dependent Metabolic Mechanisms in Drosophila melanogaster, Int. J. Food Sci. Nutr.

2019

7. Y. Peng, Q. Sun, and Y. Park, (2019) Chicoric Acid Promotes Glucose Uptake and Akt Phosphorylation via AMPK-Activated Protein Kinase á-Dependent Pathway, J. Func. Food 59: 8-15.

8. Y. Yue, P. Shen, Y. Xu, and Y. Park (2019) p-Coumaric Acid Improves Oxidative and Osmosis Stress Responses in Caenorhabditis elegansJ. Sci. Food and Ag99: 1190-1197.

9. J. S. Yang, W. Qi, S. Choi, J. M. Clark, D. Kim, and Y. Park (2019) Permethrin and Ivermectin Modulate Lipid Metabolism in Steatosis-Induced HepG2 Hepatocyte, Food Chem. Tox. 125: 595-604.

10. P. Shen, R. Zhang, D. J. McClements, and Y. Park (2019) Nanoemulsion-Based Delivery Systems for Testing Nutraceutical Efficacy Using Caenorhabditis elegans: Demonstration of Curcumin Bioaccumulation and Body- Fat Reduction, Food Res. Int. 120: 157-160.

2018

11. Y. Xu and Y. Park (2018) Application of Caenorhabditis elegans for Research on Endoplasmic Reticulum Stress, Prev. Nutr. Food Sci. 23: 275-281.

12. P. B. Chen, J. H. Kim, D. Kim, J. M. Clark, and Y. Park (2018) Conjugated Linoleic Acid (CLA) Regulates Body Composition and Locomotor Activity in Sex-Dependent Manners in Drosophila melanogaster, Lipids 53: 825-834.

13. J. Liu, Y. Peng, Y. Yue, P. Shen, and Y. Park (2018) Epigallocatechin-3-Gallate Reduces Fat Accumulation in Caenorhabditis elegansPrev. Nutr. Food Sci. 23: 214-219.

14. J. S. Yang, and Y. Park (2018) Insecticide Exposure and Development of Non-Alcoholic Fatty Liver Disease, J. Ag. Food Chem. 66: 10132-10138.

15. J. S. Yang, S. Symington, J. M. Clark, and Y. Park (2018) Permethrin, a Pyrethroid Insecticide, Regulates ERK1/2 Activation Through Membrane Depolarization-Mediated Pathway in HepG2 Hepatocytes, Food Chem. Tox. 121: 387-395. PMCID:PMC6235143

16. W. Qi, J. M. Clark, A. R. Timme-Laragy, and Y. Park (2018) Perfluorobutanesulfonic Acid (PFBS) Potentiates Adipogenesis of 3T3-L1 Adipocytes, Food Chem. Tox120: 340-345. PMCID:PMC6169790

17. R. Farias-Pereira, J. Oshiro, K.-H. Kim, and Y. Park (2018) Green Coffee Bean Extract and 5-O-Caffeoylquinic Acid Regulate Fat Metabolism in Caenorhabditis elegansJ. Func. Foods48: 586-593.

18. W. Wang, J. Yang, J. Zhang, Y. Wang, S. H. Hwang, W. Qi, D. Wan, D. Kim, J. Sun, K. Sanidad, H. Yang, Y. Park, J.-Y. Liu, X. Zhao, X. Zheng, Z. Liu, B.D. Hammock, and G. Zhang (2018) Lipidomic Profiling Reveals Soluble Epoxide Hydrolase as a Therapeutic Target of Obesity-Induced Colonic Inflammation, Proc. Nat. Acad Sci. USA115: 5283-5288.

19. F. Etemadi, A. V. Barker, M. Hashemi, O. R. Zandvakili, and Y. Park (2018) Nutrient Accumulation in Faba Bean Varieties, Comm. Soil Sci. Plant Anal. 49: 2064-2073.

20. P. B. Chen, S.-H. Yang, and Y. Park (2018) Adaptations of Skeletal Muscle Mitochondria to Obesity, Exercise, and Polyunsaturated Fatty Acids, Lipids 53: 271-278.

21. P. Shen, Y. Yue, J. Zheng, and Y. Park (2018) Caenorhabditis elegans: A Convenient In Vivo Model for Assessing the Impact of Food Bioactive Components on Obesity, Aging, and Alzheimer’s Disease, Ann. Rev. Food Sci. Tech9: 1-22.

22. P. Shen, Y. Yue, and Y. Park (2018) A Living Model for Obesity and Aging Research: Caenorhabditis elegansCrit. Rev. Food Sci. Nutr. 58: 741-754.

23. Z. Ma, A. Garrido-Maestu, C. Lee, J. Chon, D. Jeong, Y. Yue, K. Sung, Y. Park, and KC. Jeong (2018) Comprehensive In Vitro and In Vivo Evaluation of Chitosan Microparticles for Risk Assessments Using Epithelial Cells and Caenorhabditis elegans, J. Hazard. Mat. 342: 248-256.

24. X. Xiao, Q. Sun, Y. Kim, S.-H. Yang, W. Qi, D. Kim, K. S. Yoon, J. M. Clark, and Y. Park (2018) Exposure to Permethrin Promotes High Fat Diet-Induced Weight Gain and Insulin Resistance Male C57BL/6J Mice, Food Chem. Tox. 111: 405-416. PMCID: PMC5756676

25. P. Shen, Y. Yue, J. C. Kershaw, O. Wang, K.-H. Kim, D. J. McClements, and Y. Park (2018) Effects of Conjugated Linoleic Acid (CLA) on Fat Accumulation, Activity, and Proteomics Analysis in Caenorhabditis elegansFood Chem. 249: 193-201.

2017

26. Q. Sun, J. M. Clark, and Y. Park (2017) Environmental Pollutants and Type 2 Diabetes: A Review of Human Studies, Tox. Env. Chem. 99: 1283-1303.

27. P. Shen, Y. Yue, K.-H. Kim, and Y. Park (2017) Piceatannol Reduces Fat Accumulation in Caenorhabditis elegansJ. Med. Food 20: 887-894.

28. R. Zhang, W. Wu, Z. Shang, Y. Park, L. He, X. Baoshan, and D. J. McClements (2017) Effect of the Composition and Structure of Excipient Emulsion on the Bioaccessibility of Pesticides Residue in Agricultural Products, J. Ag. Food Chem65: 9128-9218.

29. J. Kim, M. Y. Park, Y. Kim, K. S. Yoon, J. M. Clark, Y. Park, and K.-Y. Whang (2017) 4,4’- Dichlorodiphenyltrichloroethane (DDT) and 4,4’-Dichlorodiphenyldichloroethylene (DDE) Inhibit Myogenesis in C2C12 Myoblasts, J. Sci. Food Ag. 97: 5176-5185.

30. Q. Sun, Y. Peng, W. Qi, J. M. Clark, and Y. Park (2017) Permethrin-Induced Insulin Resistance is Dependent on Extracellular Signal-Regulated Kinase -1 (ERK), but Not AMP-Activated Protein Kinase (AMPK) in C2C12 Myotubes, Food Chem. Tox. 109: 95-101.

31. X. Xiao, J. M. Clark, and Y. Park (2017) Permethrin Potentiates Adipogenesis via Intracellular Calcium and Endoplasmic Reticulum Stress-Mediated Mechanisms in 3T3-L1 Adipocytes, Food Chem. Tox109: 123-129.

32. Q. Sun, W. Qi, X. Xiao, S.-H. Yang, D. Kim, K. S. Yoon, J. M. Clark, and Y. Park (2017) Imidacloprid Promotes High Fat Diet-Induced Adiposity in Female C57BL/6J Mice and Enhance Adipogenesis in 3T3-L1 Adipocytes via AMPKá-Mediated Pathway, J. Ag. Food Chem65: 6572-6581. PMCID:PMC5576855

33. X. Xiao, Y. Kim, D. Kim, K. S. Yoon, J. M. Clark, and Y. Park (2017) Permethrin Alters Glucose Metabolism in Conjunction with High Fat Diet by Potentiating Insulin Resistance and Decreases Voluntary Activities in Female C57BL/6J Mice, Food Chem. Tox. 108: 161-170. PMCID:PMC5588858

34. E. Jahanzad, A. V. Barker, M. Hashemi, A. Sadeghpour, T. Eaton, and Y. Park (2017) Improving Yield and Mineral Nutrient Concentration of Potato Tubers Through Cover Cropping, Field Crops Res. 212: 45-51.

35. J. Lee, Y. Yue, Y. Park, and S.-H. Lee (2017) 3,3'-Diindolylmethane Suppresses Adipogenesis via AMPKDependent Mechanism in 3T3-L1 Adipocytes and Caenorhabditis elegansJ. Med. Food 20: 646-652.

36. W. Wang, J. Yang, Y. Nimiya, K. S. S. Lee, K. Sanidad, W. Qi, E. Sukamtoh, Y. Park, Z. Liu, and G. Zhang (2017) ù-3 Polyunsaturated Fatty Acids and Their Cytochrome P540-Derived Metabolites Suppress Colorectal Tumor Development in Mice, J. Nutr. Biochem. 48: 29-35.

37. P. Shen, Y. Yue, Q. Sun, N. Kasireddy, K.-H. Kim, and Y. Park (2017) Piceatannol Extends the Lifespan of Caenorhabditis elegans Via DAF-16, Biofactors43: 379-387.

38. X. Xiao, J. M. Clark, and Y. Park (2017) Potential Contribution of Insecticide Exposure and Development of Obesity and Type 2 Diabetes, Food Chem. Tox. 105: 456-474.

39. S. J. Hur, H. S. Kim, Y. Y. Bahk, and Y. Park (2017) Overview of Conjugated Linoleic Acid Formation and Accumulation in Animal Products, Livestock Sci. 195: 105-111.

40. L. Salvia-Trujillo, B. Fumiaki, Y. Park, and D. J. McClements (2017) Influence of Lipid Droplet Size on the Oral Bioavailability of Vitamin D2 Encapsulated in Emulsions: An In Vitro and In Vivo Study, Food Func8: 767-777.

41. Z. Zhang, R. Zhang, Q. Sun, Y. Park, and D. J. McClements (2017) Confocal Fluorescence Mapping of pH Profile Inside Hydrogel Beads (Microgels) with Controllable Internal pH Values, Food Hydrocolloids 65: 198- 205.

42. P. Shen, T.-H. Hsieh, Y. Yue, Q. Sun, J. M. Clark, and Y. Park (2017) Deltamethrin Increases the Fat Accumulation in 3T3-L1 Adipocytes and Caenorhabditis elegans, Food Chem. Tox. 101: 149-156.

43. W. Wang, J. Yang, W. Qi, H. Yang, C. Wang, B. Tan, B. D. Hammock, Y. Park, D. Kim, and G. Zhang (2017) Lipidomic Profiling of High-Fat Diet-Induced Obesity in Mice: Importance of Cytochrome P450-Derived Fatty Acid Epoxides, Obesity 25: 132-140.

2016

44. Q. Sun, X. Xiao, Y. Kim, D. Kim, K. S. Yoon, J. M. Clark, and Y. Park (2016) Imidacloprid Promotes High Fat Diet-Induced Adiposity and Insulin Resistance in Male C57BL/6J Mice, J. Ag. Food Chem64: 9293-9306. PMCID:PMC5325319

45. J. Kim, M. Y. Park, H. K. Kim, Y. Park, and K.-Y. Whang (2016) Cortisone and Dexamethasone Inhibit C2C12 Myogenesis by Modulating AKT and mTor Signaling Pathway, Biosci. Biotech. Biochem. 80: 2093-2099. DOI: 10.1080/09168451.2016.1210502

46. Y. Kim and Y. Park (2016) Conjugated Linoleic Acid (CLA) Promotes Endurance Capacity Via Peroxisome Proliferator-Activated Receptor δ-Mediated Mechanism in Mice, J. Nutr. Biochem. 38: 125-133.

47. Y. Kim, D. J. Good, and Y. Park (2016) Conjugated Linoleic Acid (CLA) Improves Muscle Metabolism via Stimulating Mitochondrial Biogenesis Signaling in Genetically Induced Inactive Adult-Onset Obese Mice, Eur. J. Lipid Sci. Tech. 118: 1305-1316.

48. H. M. Abdulla, P. Akabari, B. Paulose, D. Schnell, W. Qi, Y. Park, A. Pareek, and O. P. Dhankher (2016) Transcriptome Profiling of Camelina sativa to Identify Genes Involved in Triacylglycerol Biosynthesis and Accumulation in the Developing Seeds, Biotech. Biofuels9: 136.

49. J. Kim, Q. Sun, Y. Yue, K. S. Yoon, K.-Y. Whang, J. M. Clark, and Y. Park (2016) 4,4’- Dichlorodiphenyltrichloroethane (DDT) and 4,4’-Dichlorodiphenyldichloroethylene (DDE) Promote Adipogenesis in 3T3-L1 Adipocyte Cell Culture, Pesticide Biochem. Phys131: 40-45.

50. Q. Sun, W. Qi, J. J. Yang, K. S. Yoon, J. M. Clark, and Y. Park (2016) Fipronil Promotes Adipogenesis Via AMPKα-Mediated Pathway in 3T3-L1 Adipocytes, Food Chem. Tox. 92: 217-223.

51. Q. Sun, Y. Yue, P. Shen, J. J. Yang, and Y. Park (2016) Cranberry Bioactives Decrease Fat Accumulation in C. elegansJ. Med. Food. 19: 427-433.

52. J. H. Kim, Y. Kim, Y. J. Kim and Y. Park (2016) Conjugated Linoleic Acid-Potential Health Benefits as a Functional Food Ingredient, Ann. Rev. Food Sci. Tech. 7:221-244.

53. L. Cui, H. T. Cho, D. J. McClements, E. A. Decker, and Y. Park (2016) Effects of salts on oxidative stability of lipids in oil-in-water emulsion, Food Chem. 197: 1130-1135.

54. D. Colmenares, Q. Sun, P. Shen, Y. Yue, D. J. McClements, and Y. Park (2016) Delivery of Dietary Triglycerides to Caernohabditis elegans Using Lipid Nanoparticles: Nanoemulsion-Based Delivery Systems, Food Chem202: 451-457.

55. Y. Kim, J. Kim, K.-Y. Whang, and Y. Park (2016) Impact of Conjugated Linoleic Acid (CLA) on Skeletal Muscle Metabolism, Lipids 51: 159-178.

2015

56. Y. Kim, D. Kim, D. J. Good, and Y. Park (2015) Effects of Post-Weaning Administration of Conjugated Linoleic Acid on Development of Obesity in Nescient Basic Helix-Loop-Helix 2 Knockout Mice, J. Ag. Food Chem. 63: 5212-5223.

57. L. Salvia-Trujillo, Q. Sun, B.-H. Um, Y. Park, and D. J. McClements (2015) In Vitro and In Vivo Study of Fucoxanthin Bioavailability From Nanoemulsion-Based Delivery Systems: Impact of Lipid Carrier type, J. Func. Foods 17: 293-304.

58. J. H. Kim, Y. J. Kim, and Y. Park (2015) Conjugated Linoleic Acid and Postmenopausal Women’s Health, J. Food Sci. 80:R1137-R1143.

59. Y. Kim and Y. Park (2015) Conjugated Linoleic Acid (CLA) Stimulates Mitochondrial Biogenesis Signaling by the Upregulation of Peroxisome Proliferator-Activated Receptor- γ Coactivator 1α in C2C12 Cells, Lipids 50: 329-338.

60. J. Wong, Y. Kim, YH. Park, S.-H. Lee, S. J. Baek, and Y. Park (2015) Isomer Specificity of Conjugated Linoleic Acid on Suppression of Osteosarcomas, J. Nature Sci. 1: e67.

61. X. Xiao, J. Kim, Q. Sun, D. Kim, C.-S. Park, T.-S. Lu, and Y. Park (2015) Preventive Effects of Cranberry Products on Experimental Colitis Induced by Dextran Sulfate Sodium in Mice, Food Chem. 167: 438-446.

62. K.-J. Kim, J. Lee, Y. Park, and S.-H. Lee (2015) ATF3 Mediates Anti-Cancer Activity of trans-10, cis-12- Conjugated Linoleic Acid in Human Colon Cancer Cells, Biomol. Therap. 23: 134-140.

2014

63. J. Kim, YH Park, K. S. Yoon, J. M. Clark, and Y. Park (2014) Permethrin alters adipogenesis in 3T3-L1 adipocytes and causes insulin resistance in C2C12 myotubes, J. Biochem. Mol. Tox. 28:418-424.

64. M. Lahlou, R. Kanneganti, L. J. Massingill, G. A. Broderic, Y. Park, M. W. Pariza, J. D. Ferguson, and Z. Wu (2014) Grazing Increases the Concentration of Conjugated Linoleic Acid in Milk of Dairy Cows, Animal: Int. J. Animal Biosci. 8:1091-1200.

65. J. Kim, YH. Park, and Y. Park (2014) trans-10,cis-12 Conjugated Linoleic Acid Promotes Osteoblastogenesis via SMAD Mediated Mechanism in Bone Marrow Mesenchymal Stem Cells, J. Func. Foods 8:367-376. PMCID: PMC4095819

66. H. T. Cho, L. Salvia-Trujillo, J. Kim, Y. Park, H. Xiao, and D. J. McClements (2014) Influence of Droplet Size and Composition on Bioavailability of Long Chain Fatty Acids and Coenzyme Q10: An In Vivo Study, Food Chem. 156:117-122.

2013

67. J. Kim, YH. Park, K. S. Yoon, J. M. Clark, and Y. Park (2013) Imidacloprid, a neonicotinoid insecticide, induces insulin resistance, J. Toxicol. Sci. 38: 655-660.

68. YH. Park, Y. Kim, K. S. Yoon, J. Kim, J. M. Clark, J. Lee, and Y. Park (2013) A Neonicotinoid Insecticide, Imidacloprid, Potentiates Lipid Accumulation in 3T3-L1 Adipocytes, J. Agric. Food Chem61:255-259.

69. YH. Park, J. Kim, A. G. Scrimgeour, M. L. Condlin, D. Kim and Y. Park (2013) Conjugated Linoleic Acid and Calcium Co-Supplementation Improves Bone Health in Ovariectomized Mice, Food Chem. 140:280-288. PMCID: PMC3625250

70. J. H. Kim, YH. Park, D. Kim, D. J. Good, and Y. Park (2013) Dietary Conjugated Nonadecadienoic Acid Prevents Adult-Onset Obesity in Nescient Basic Helix-Loop-Helix 2 Knockout Mice, J. Nutr. Biochem. 24:556- 566.

71. J. Kim, YH. Park, S.-H. Lee, and Y. Park (2013) trans-10,cis-12 Conjugated Linoleic Acid Promotes Bone Formation by Inhibiting Adipogenesis by Peroxisome Proliferator Activated Receptor-γ Dependent Mechanisms and by Directly Enhancing Osteoblastogenesis From Bone Marrow Mesenchymal Stem Cells, J. Nutr. Biochem.  24:672-679. PMCID: PMC3482420

2012

72. J. H. Kim, D. Gilliard, D. J. Good, and Y. Park (2012) Preventive Effects of Conjugated Linoleic Acid on Obesity by Improved Physical Activity in Nescient Basic Helix-Loop-Helix 2 Knockout Mice During Growth Period, Food Function 3:1280-1285.

73. Y. Li, J. Kim, Y. Park, and D. J. McClements (2012) Modulation of Lipid Digestibility using Structured Emulsion-Based Delivery Systems: Comparison of in vivo and in vitro Measurements, Food Function 3:528- 536.

74. J. H. Kim, J. Kim, and Y. Park (2012) trans-10,cis-12 Conjugated Linoleic Acid Enhances Endurance Capacity by Increasing Fatty Acid Oxidation and Reducing Glycogen Utilization in Mice, Lipids 47: 855-863.

75. J. H. Kim, YH. Park, D. Kim, and Y. Park (2012) Dietary Influences on Physical Activity and Energy Expenditure in C57BL/6J Mice, J. Food Sci. 77:H63-H68.

76. A. Dilzer, and Y. Park (2012) Implication of Conjugated Linoleic Acid (CLA) in Human Health, Crit. Rev. Food Sci. Nutr. 52: 488-513.

77. YH. Park, and Y. Park (2012) Conjugated Fatty Acids Increase Energy Expenditure by Increasing Voluntary Movement in Mice, Food Chem. 133: 400-409.

2011

78. YH. Park, M. Terk, and Y. Park (2011) Interaction between Dietary Conjugated Linoleic Acid (CLA) and Calcium Supplementation on Bone and Fat Mass, J. Bone Miner. Meta. 29: 268-278.

79. K.-H. Kim, and Y. Park (2011) Food Components with Anti-Obesity Effects, Ann. Rev. Food Sci. Tech. 2: 237- 257.

2010

80. YH. Park, and Y. Park (2010) Conjugated Nonadecadienoic Acid is More Potent Than Conjugated Linoleic Acid on Body Fat Reduction, J. Nutr. Biochem. 21: 764-773.

81. E. A. Decker, and Y. Park (2010) Healthier meat products as functional food, Meat Science 86: 49-55.

82. Y. Park, K. J. Albright, J. M. Storkson, W. Liu, and M. W. Pariza (2010) Effects of Dietary Conjugated Linoleic Acid (CLA) on Spontaneously Hypertensive Rats, J. Functional Foods 2: 54-59.

2009

83. Y. Park (2009) Conjugated Linoleic Acid (CLA): Good or bad trans fat? J. Food Comp. Anal22S: S4-S12.

84. Y. Park, and M. W. Pariza (2009) Bioactivities and Potential Mechanisms of Action for Conjugated Fatty Acids, Food Sci. Biotech. 18: 586-593.

85. D. J. McClements, E. A. Decker, Y. Park, and J. Weiss (2009) Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods, Crit. Rev. Food Sci. Nutr. 49: 577-606.

86. S. J. Hur, F. Whitcomb, S. Rhee, YH. Park, D. J. Good, and Y. Park (2009) Effects of trans-10,cis-12 Conjugated Linoleic Acid on Body Composition in Genetically Obese Mice, J. Med. Food 12: 56-63.

87. D. J. McClements, E. A. Decker, and Y. Park (2009) Controlling Lipid Bioavailability through Physicochemical and Structural Approaches, Crit. Rev. Food Sci. Nutr. 49: 48-67.

2008

88. YH. Park, M. W. Pariza, and Y. Park (2008) Co-supplementation of Dietary Calcium and Conjugated Linoleic Acid (CLA) Improves Bone Mass in Mice, J. Food Sci. 73: C556-C560.

89. D. J. McClements, E. A. Decker, Y. Park, and J. Weiss (2008) Designing food structure to control stability, digestion, release and absorption of lipophilic food components, Food Biophysics 3: 219-228.

90. S. Mahadevan, YH. Park, and Y. Park (2008) Modulation of Cholesterol Metabolism by Ginkgo biloba L. Nuts and their Extract, Food Res. Int. 41: 89-95.

91. S. Mahadevan, and Y. Park (2008) Multifaceted Therapeutic Benefits of Ginkgo biloba L.: Chemistry, Efficacy, Safety and Uses, J. Food Sci. 73: R14-19.

2007

92. Y. Park, K. J. Albright, J. M. Storkson, W. Liu, YH. Park, and M. W. Pariza (2007) Influence of Stearidonic Acid on Lipoprotein Secretion and Fatty Acid Composition in HepG2 Cells, J. Food Lipids 14: 366-376.

93. Y. Park, K. J. Albright, J. M. Storkson, W. Liu, and M. W. Pariza (2007) Conjugated Linoleic Acid (CLA) Prevents Body Fat and Weight Gain in an Animal Model, J. Food Sci. 72: S612-S617.

94. S. J. Hur and Y. Park (2007) Effects of Conjugated Linoleic Acid on Bone Formation and Rheumatoid Arthritis, Eur. J. Pharmacol. 568: 16-24.

95. G. Y. Park, S. Mun, YH. Park, S. Rhee, E. A. Decker, J. Weiss, D. J. McClements, and Y. Park (2007) Influence of Encapsulation of Emulsified Lipids with Chitosan on their In Vivo Digestibility, Food Chem. 104: 761-767.

96. Y. Park, M. Yang, J. M. Storkson, K. J. Albright, W. Liu, M. E. Cook, and M. W. Pariza (2007) Effects of Conjugated Linoleic Acid (CLA) Isomers on Serum Tumor Necrosis Factor-α Concentration in Mice, J. Food Biochem. 31: 252-265.

97. Y. Park, and M. W. Pariza (2007) Mechanisms of Body Fat Modulation by Conjugated Linoleic Acid (CLA), Food Res. Int. 40: 311-323.

98. Y. Park, Y. L. Ha, and M. W. Pariza (2007) π-Complex Formation of Conjugated Linoleic Acid (CLA) with Iron, Food Chem. 100: 972-976.

2006

99. G. Li, D. Butz, B. Dong, Y. Park, M. W. Pariza, and M. E. Cook (2006) Selective Conjugated Fatty Acids Inhibit Guinea Pig Platelet Aggregation, Eur. J. Pharmacol. 545: 93-99.

100. G. Li, B. Dong, D. E. Butz, Y. Park, M. W. Pariza, and M. E. Cook (2006) NF-κB Independent Inhibition of Lipopolysaccharide-Induced Cyclooxygenase by a Conjugated Linoleic Acid Cognate, Biochim. Biophys. Acta 1761: 969-972.

101. S.-H. Lee, K. Yamaguchi, J.-S. Kim, T. E. Eling, Y. Park, and S. J. Baek (2006) Conjugated Linoleic Acid Stimulates an Anti-Tumorigenic Protein NAG-1 in an Isomer Specific Manner, Carcinogenesis 27: 972-981.

102. S. Mun, E. A. Decker, Y. Park, J. Weiss, and D. J. McClements (2006) Influence of Interfacial Composition on In Vitro Digestibility of Emulsified Lipids: Potential Mechanisms for Chitosan’s Ability to Inhibit Fat Absorption, Food Biophysics 1:21-29.

2005

103. Y. Park, K. J. Albright, and M. W. Pariza (2005) Effects of Conjugated Linoleic Acid on Long Term Feeding in Fischer 344 Rats, Food Chem. Tox. 43: 1273-1279.

104. J. M. Storkson, Y. Park, M. E. Cook, and M. W. Pariza (2005), Effects of trans-10,cis-12 Conjugated Linoleic Acid (CLA) on Cognates on Apolipoprotein B Secretion in HepG2 Cells, Nutr. Res. 25: 387-399.

105. Y. Park, J. M. Storkson, K. J. Albright, W. Liu, and M. W. Pariza (2005) Biological Activities of Conjugated Fatty Acids: Conjugated Eicosadienoic (conj. 20:2Δc11,t13/ t12,c14), Eicosatrienoic (conj. 20:3Δc8,t12,c14), and Heneicosadienoic (conj. 21:2Δc12,t14/ c13,t15) Acids and Other Metabolites of Conjugated Linoleic Acid, Biochim. Biophys. Acta 1687: 120-129.

Prior to joining the University of Massachusetts

106. Y. Park, J. M. Storkson, W. Liu, K. J. Albright, M. E. Cook, and M. W. Pariza (2004) Structure-Activity Relationship of Conjugated Linoleic Acid and its Cognates in Inhibition of Heparin-releasable Lipoprotein Lipase and Glycerol Release from Fully Differentiated 3T3-L1 Adipocytes, J. Nutr. Biochem.15: 561-569.

107. X. Xu, J. Storkson, S. Kim, K. Sugimoto, Y. Park, and M. W. Pariza (2003), Early Effects of Dietary Conjugated Linoleic Acid on Mouse Adipose Tissue Include Inhibiting Lipoprotein Lipase and Glucose Metabolism but Not Enhancing Lipolysis, J. Nutr. 133: 663-667.

108. K. Kang, W. Liu, K. J. Albright, Y. Park, and M. W. Pariza (2003), Trans-10, cis-12 CLA Inhibits Differentiation of 3T3-L1 Adipocytes and Decreases PPARγ Expression, Biochem. Biophy. Res. Comm. 303: 795-799.

109. L. D. Whigham, D. E. Bjorling, A. Higbee, Y. Park, M. W. Pariza, and M. E. Cook (2002), Decreased Antigen-induced Eicosanoid Release in Conjugated Linoleic Acid (CLA)-fed Guinea Pigs, Am. J. Physiol. 284(4): R1104-R1112.

110. Y. Choi, Y. Park, J. M. Storkson, M. W. Pariza, and J. M. Ntambi (2002), Inhibition of Stearoyl-CoA Desaturase Activity by the Cis-9,trans-11 Isomer and the Trans-10,cis-12 Isomer of Conjugated Linoleic Acid in MDA-MB-231 and MCF-7 Human Breast Cancer Cells, Biochem. Biophy. Res. Comm. 294 (4): 785-790.

111. M. R. Kim, Y. Park, K. J. Albright, and M. W. Pariza (2002), Differential Responses of Hamsters and Rats Fed High-fat or Low-fat Diets Supplemented with Conjugated Linoleic Acid, Nutr. Res. 22: 715-722.

112. J. M. Ntambi, Y. Choi, Y. Park, J. M. Peters, and M. W. Pariza (2002), Effects of Conjugated Linoleic Acid (CLA) on Immune Responses, Body Composition and Stearoyl-CoA Desaturase, Can. J. Appl. Physiol. 27 (6): 617-627.

113. Y. Park, K. J. Albright, Z. Y. Cai, and M. W. Pariza (2001), Comparison of Methylation Procedures for Conjugated Linoleic Acid (CLA) and Artifact Formation by Commercial Trimethylsilyl Diazomethane, J. Agri. Food Chem.49: 1158-1164.

114. M. W. Pariza, Y. Park, and M. E. Cook (2001), The Biologically Active Isomers of Conjugated Linoleic Acid, Prog. Lipid Res. 40: 283-298.

115. Y. Choi, Y. Park, M. W. Pariza, and J. M. Ntambi (2001), Regulation of Stearoyl-CoA Desaturase Activity by the trans-10,cis-12 Isomer of Conjugated Linoleic Acid in HepG2 cells, Biochem. Biophy. Res. Comm. 284: 689-693.

116. Y. Park, and M. W. Pariza (2001), The Effects of Dietary Conjugated Nonadecadienoic Acid (CNA) on Body Composition in Mice, Biochim. Biophys. Acta 1533: 171-174.

117. J. M. Peters, Y. Park, F. J. Gonzalez, and M. W. Pariza (2001), Influence of Conjugated Linoleic Acid on Body Composition and Target Gene Expression in Peroxisome Proliferator-Activated Receptor á (PPAR á)- Null Mice, Biochim. Biophys. Acta 1533: 233-242.

118. Y. Park, and M. W. Pariza (2001), Lipoxygenase Inhibitors Enhance Body Fat Reduction in Mice by Conjugated Linoleic Acid and Inhibit Heparin-Releasable Lipoprotein Lipase Activity in 3T3-L1 Adipocytes, Biochim. Biophys. Acta 1534: 27-33.

119. M. Evans, Y. Park, M. Pariza, L. Curtis, B. Kuebler, and M. McIntosh (2001), Trans-10,cis-12 Conjugated Linoleic Acid Reduces Triglyceride Content While Differentially Affecting Peroxisome Proliferator Activated Receptor á2 and aP2 Expression in 3T3-L1 Preadipocytes, Lipids 36: 1223-1232.

120. M. W. Pariza, Y. Park, and M. E. Cook (2000), Mechanisms of Action of Conjugated Linoleic Acid: Evidence and Speculation, Proc. Soc. Exp. Biol. Med223: 8-13.

121. Y. Park, J. M. Storkson, J. M. Ntambi, M. E. Cook, C. J. Sih, and M. W. Pariza (2000), Inhibition of Hepatic Stearoyl-CoA Desaturase Activity by trans-10,cis-12 Conjugated Linoleic Acid and its Derivatives, Biochim. Biophys. Acta, 1486: 285-292.

122. Y. Choi, Y.-C. Kim, Y.-B. Han, Y. Park, M. W. Pariza, and J. M. Ntambi (2000), The Trans-10,cis-12 Isomer of Conjugated Linoleic Acid Downregulates Stearoyl-CoA Desaturase Gene Expression in 3T3-L1 Adipocytes, J. Nutr.130: 1920-1924.

123. Y. Park, J. M. Storkson, K. J. Albright, W. Liu, and M. W. Pariza (1999), Evidence That the Trans-10, Cis- 12 Isomer of Conjugated Linoleic Acid Induces Body Composition Changes in Mice, Lipids34: 235-241.

124. Y. Park, K. J. Albright, J. M. Storkson, W. Liu, M. E. Cook, and M. W. Pariza (1999), Changes in Body Composition in Mice During Feeding and Withdrawal of Conjugated Linoleic Acid, Lipids34: 243-248.

125. M. W. Pariza, Y. Park, and M. E. Cook (1999), Conjugated Linoleic Acid and the Control of Cancer and Obesity, Toxicological Sciences52(suppl): 107-110.

126. Y. Park and M. W. Pariza (1998), Evidence That Commercial Calf and Horse Sera Can Contain Substantial Amounts of trans-10, cis-12 Conjugated Linoleic Acid, Lipids33: 817-819.

127. Y. Park, K. J. Albright, W. Liu, J. M. Storkson, M. E. Cook, and M. W. Pariza (1997), Effects of Conjugated Linoleic Acid on Body Composition in Mice, Lipids32: 853-858.

128. B. -H. Han, D.-Y. Suh, H. O. Yang, Y.-H. Park, Y. H. Kang, and Y. C. Kim (1994), Synthesis and Antiplatelet Effects of the New Antithrombotic Agent Aspalatone with Low Ulcerogenicity, Drug Res. (Arzneimittelforschung.)44(II): 1122-1126.

129. C. C. Miller, Y. Park, M. W. Pariza, and M. E. Cook (1994), Feeding Conjugated Linoleic Acid to Animals Partially Overcomes Catabolic Responses Due to Endotoxin Injection, Biochem. Biophy. Res. Comm.198: 1107-1112.

130. M. E. Cook, C. C. Miller, Y. Park, and M. W. Pariza (1993), Immune Modulation by Altered Nutrient Metabolism: Nutritional Control of Immune-induced Growth Depression, Poultry Sci., 72: 1301-1305.

131. B. H. Han, M. K. Park, and Y.-H. Park (1990), A Lignan from Rubia akaneArch. Pharm. Res., 13(3): 289- 291.