Yeonhwa Park

Professor, Francis Chair

Faculty
Yeonhwa Park
Contact
Email
Email
Phone
Location
Room 252, Chenoweth Laboratory

Field of Study

Functional foods (bioactive food components), biologically beneficial effects of conjugated linoleic acid, obesity, and environmental contaminants on  obesity and aging

Research

My current research interests can be divided into two categories; first, food bioactives for prevention of obesity and aging and secondly, investigating environmental contaminants and development of obesity and type 2 diabetes.

A. Food Bioactives for Prevention of Obesity and Aging

This research interest started as I have worked on Conjugated Linoleic Acid (CLA). CLA was originally identified unexpectedly as an anti-cancer principal from ground beef in 1987. Since then, CLA has shown other biologically beneficial activities, including reducing body fat. In addition, I have expanded my research focus for many other food bioactives for obesity prevention. For this, I have used multiple experimental models, such as rodents, Caenorhabditis elegans, Drosophila, as well as many types of mammalian tissue culture models. Among them, C. elegans is also used for identifying potential food bioactives for aging study as this model has many benefits for research for aging, including a short life-span.

B. Environmental Contaminants and Development of Obesity

In line with above mentioned research interest on obesity, it is important to note that current epidemic of obesity and related diseases cannot be explained completely by considering changes in societal, behavioral, or dietary habits of individuals. Recently, there is an emerging body of evidence indicating that exposure to persistent organic pollutants, including insecticides, were positively correlated with e­­xcessive weight gain and altered glucose homeostasis. However, the detailed molecular mechanism regarding how these environmental chemicals perturb metabolism and ultimately contribute to the development of obesity and other related diseases have yet to be elucidated fully. Thus my group is investigating the role of insecticides on development of obesity and type 2 diabetes.

Teaching

FS150 Science of Food (Gen. Ed. BS)
FS270 Biology of Food in Human Health
FS750 Bioactive Food Components

Awards

2017 & 2018 Clarivate Highly Cited Researcher (Agriculture)

2015 Faculty Convocation Award, University of Massachusetts

2015 Timothy Mounts Award, American Oil Chemists’ Society

2014 Thomson Reuters Highly Cited Researcher (Agriculture)

2014 ASN's Korean Nutrition Society Award

2009 Armstrong Fund for Science Award at UMass

ILSI 2007 Future Leader Award

Outstanding Division Volunteer Award 2007, 2008 & 2011 IFT Food Chemistry Division

American Oil Chemists Society 2003 Young Scientist Research Award

Publications

Refereed Journals

2024 

  1. J. Cho, and Y. Park (2024) Development of Aging Research in Caenorhabditis elegans: From Molecular Insights to Therapeutic Application for Healthy Aging, Curr. Res. Food Sci.  9: 100809. 

  2. M. Marin, K. M. Annunziato, M. D. Tompach, W. Liang, S. M Zahn, S. Li, J. J. Doherty, J. Lee, J. M. Clark, Y. Park, and A. R. Timme-Laragy (2024) Maternal PFOS exposure affects offspring development in NrF2-dependent and independent ways in zebrafish (Danio rerio), Aqua. Tox. 271: 106923.  

  3. A. T. Kim, S. Li, Y. Kim, Y.-J. You, and Y. Park (2024) Food preference-based screening method for identification of effectors of substance use disorders using Caenorhabditis elegans, Life Sciences 345: 122580. 

  4. M. D. Tompach, C. K. Gridley, S. Li, Y. Park, J. M. Clark, and A. R. Timme-Laragy (2024) Comparing the effects of developmental exposure to alpha lipoic acid (ALA) and perfluorooctanesulfonic acid (PFOS) in zebrafish (Danio rerio), Food Chem. Tox. 186: 114560. 

2023 

  1. A. T. Kim and Y. Park (2023) Trifuhalol A, a phlorotannin from the brown algae Agarum cribrosum, reduces adipogenesis of human primary adipocytes through Wnt/β-catenin and AMPK-dependent pathways, Curr. Res. Food Sci. 7: 100646. 

  2. J. Cho and Y. Park (2023) Kahweol, a coffee diterpene, increases lifespan via insulin/insulin-like growth factor-1 and AMP-activated protein kinase signaling pathways in Caenorhabditis elegans, Curr. Res. Food Sci. 7: 100618. 

  3. J. Zhang, J. Yang, C. N. Duval, M. L. Edin, A. Williams, L. Lei, M. Tu, E. Pourmand, R. Song, J. P. Graves, L. M. DeGraff, J. J.-L. Wong, Y. Wang, Q. Sun, K. Z. Sanidad, S. Wong, Y. Han, Z. Zhang, K. S. S. Lee, Y. Park, H. Xiao, Z. Liu, E. A. Decker, W. Cui, D. C. Zeldin, and G. Zhang (2023) CYP eicosanoid pathway mediates colon cancer-promoting effects of dietary linoleic acid, FASEB J. 37: e23009. 

  4. D.-H. Jeong, D.-W. Jung, C.-H. Jang, U.-J. Kim, Y. Park, Y. Park, and HS. Lee (2023) Chlorpropham, a carbamate ester herbicide, has an endocrine-disrupting potential by inhibiting the homodimerixation of human androgen receptor, Environ. Pollut. 325: 121437. 

2022 

  1. Z. Qi, J. Lin, R. Gao, W. Wu, Y. Zhang, X. Wei, X. Xiao, H. Wang, Y. Peng, J. M. Clark, Y. Park, and Q. Sun (2022) Transcriptome analysis provides insight into deltamethrin-induced fat accumulation in 3T3-L1 adipocytes, Pest. Biochem. Physiol. 184: 105115.  

  2. H.-S. Lee, D. Amarakoon, G. Tamia, Y. Park, D. Smolensky, and S.-H. Lee (2022) Pendimethalin induces apoptotic cell death through activating ER stress-mediated mitochondrial dysfunction in human umbilical vein endothelial cells, Food Chem. Tox. 168: 113370.  

  3. H.-S. Lee, H.-J. Song, Y. Park, D. Smolensky, and S.-H. Lee (2022) Permethrin inhibits tube formation and viability of endothelial cells, J. Sci. Food Ag. 102: 4079-4085.  

  4. M. A. Roy, C. K. Gridley, S. Li, Y. Park, and A. R. Timme-Laragy (2022) Nrf2a dependent and independent effects of early life exposure to 3,3’-dichlorobiphenyl (PCB-11) in zebrafish (Danio rerio), Aquatic Tox. 249: 106219. PMCID: PMC9701526 

  5. S. Y. Lee, D. Y. Lee, J. H. Kang, J. W. Jeong, J. H. Kim, H. W. Kim, D. H. Oh, J.-M. Kim S.-J. Rhim, G.-D. Kim, H. S. Kim, Y. D. Jang, Y. Park, and S. J. Hur (2022) Alternative experimental approaches to reduce animal use in biomedical studies J. Drug Deliv. Sci. Technol. 68: 103131.  

  6. Y. Park, A. Suvorov, S. B. Symington, and J. M. Clark (2022) Membrane polarization in non-neuronal cells as potential mechanism of metabolic disruption by depolarizing insecticides, Food Chem. Tox. 160: 112804.  

  7. K. M. Annunziato, M. Marin, W. Liang, S. Conlin, W. Qi, J. Doherty, J. Lee, J. M. Clark, Y. Park, and A. R. Timme-Laragy (2022) The Nrf2a pathway impacts on zebrafish offspring development with maternal preconception exposure to perfluorobutanesulfonic acid, Chemosphere 287: 132121. 

2021 

  1. Y. Yue, S. Li, P. Shen, and Y. Park (2021) Caenorhabditis elegans as a model for obesity research, Curr. Res. Food Sci. 4: 692-697. 

  2. Y. Yue, G. Hao, J. Cho, and Y. Park (2021) Curcumin Reduced Fat Accumulation in Caenorhabditis elegans, Curr. Res. Food Sci. 4: 551-556. 

  3. S. J. Baek, B. Hammock, I. K. Hwang, Q. X. Li, N. Moustaid-Moussa, Y. Park, S. Safe, N. Suh, S. S. Yi,  D. C. Zeldin, Q. Zhong, J. A. Bradbury, M. L. Edin, J. P. Graves, H. Y. Jung, Y. H. Jung, M.-B. Kim, W. Kim, J. Lee, H. Li, J.-S. Moon, I. D. Yoo, Y. Yue,  J.-Y. Lee, and H. J. Han (2021) Natural Products in the Prevention of Metabolic Diseases: Lessons Learned from the 20th Frontier Scientists Workshop, Nutrients 13: 1881. 

  4. Y. Yue, J. Wang, P. Shen, K.-H. Kim, and Y. Park (2021) Methylglyoxal influences development of Caenorhabditis elegans via lin-41-dependent pathway, Food Chem. Tox. 152: 112238. 

  5. J. Bai, R. Farias-Pereira, M. Jang, Y. Zhang, S. M. Lee, Y.-S. Kim, Y. Park, J. B. Ahn, G.-H. Kim, K.-H. Kim (2021) Azelaic acid promotes Caenorhabditis elegans longevity at low temperature via an increase in fatty acid desaturation, Pharm. Res. 38: 15-26. 

  6. E. Y. Jung, S. Y. Lee, D. Y. Lee, O. Y. Kim, Y. Park, and S. J. Hur (2021) Effect of encapsulated edible halophyte with different biopolymers on the inhibition of sodium absorption in mouse, Food Sci. Nutr. 9: 1972-1979. 

  7. J. Kim, B. Barbagallo, K. Annunziato, R. Farias-Pereira, J. Doherty, J. Lee, J. Zina, C. Tindall, R. Aresco, C. McVey, M. Johnstone, K. Sant, A. Timme-Laragy, Y. Park, and J. Clark (2021) Maternal Preconception PFOS Exposure of Drosophila melanogaster Alters Reproductive Capacity, Development, Morphology and Nutrient Regulation, Food Chem. Tox. 151: 112153. PMCID: PMC8085153 

  8. R. Farias-Pereira, L. Young, and Y. Park (2021) Neuroprotective effects of green coffee bean extract against Alzheimer’s and Parkinson’s disease: a mini review, Food Life 2021: 1-7. 

  9. K. E. Sant, K. Annunziato, S. Conlin, G. Teicher, P. B. Chen, O. Venezia, G. B. Downes, Y. Park, and A. R. Timme-Laragy (2021) Development exposures to perfluorooctanesulfonic acid (PFOS) impact embryonic nutrition, pancreatic morphology, and adiposity in the zebrafish, Danio rerio, Env. Poll. 275: 116644. 

2020 

  1. D. Y. Lee, S. Y. Lee, H. J. Kang, Y. Park, and S. J. Hur (2020) Development of effective heparin extraction method from pig by-products and analysis of their bioavailability, J. Anim. Sci. Technol. 62: 933-947. 

  2. W. Qi, J. M. Clark, A. R. Timme-Laragy, and Y. Park (2020) Perfluorobutanesulfonic acid (PFBS) Induces Fat Accumulation in HepG2 Human Hepatoma, Tox. Env. Chem. 102: 585-606. PMCID: PMC7986581 

  3. J. Zhang, M. Freund, M. D. Culler, R. Yang, P. B. Chen, Y. Park, E. A. Decker, and G. Zhang (2020) How to Stabilize w-3 Polyunsaturated Fatty Acids (PUFAs) in an Animal Feeding Study? – Effects of Temperature, Oxygen Level, Antioxidant on Oxidative Stability of w-3 PUFAs in a Mouse Diet, J. Ag. Food Chem. 68: 13146-13153. 

  4. J. Bai, R. Farias-Pereira, Y. Zhang, M. Jang, Y. Park, and K.-H, Kim (2020) C. elegans ACAT regulates lipolysis and its-related lifespan in fasting through modulation of the genes in lipolysis and insulin/IGF-1 signaling, Biof. 46: 754-765. 

  5. R. Farias-Pereira, Z. Zhang, C.-S. Park, D. Kim, K.-H. Kim, and Y. Park (2020) Butein Inhibits Lipogenesis in Caenorhabditis elegans, Biofactors 46: 777-787. 

  6. Y. Yue, S. Li, Z. Qian, R. Farias-Pereira, J. Lee, J. J. Doherty, Z. Zhang, Y. Peng, J. M. Clark, A. R. Timme-Laragy, and Y. Park (2020) Perfluorooctanesulfonic acid (PFOS) and perfluorobutanesulfonic acid (PFBS) impaired reproduction and altered offspring physiological functions in Caenorhabditis elegans, Food Chem. Tox. 145: 111695. PMCID: PMC7554236 

  7. W. Qi, J. M. Clark, A. R. Timme-Laragy, and Y. Park (2020) Per- and Polyfluoroalkyl Substances (PFAS) and Obesity, Type 2 Diabetes and Non-alcoholic Fatty Liver Disease: A Review of Epidemiologic Findings, Tox. Env. Chem. 102: 1-36. PMCID: PMC7723340 

  8. M. Xie, J. Yang, J. Zhang, H. Sherman, Z. Zhang, L. M. Minter, B. Hammock, Y. Park, and G. Zhang (2020) Effects of Linoleic Acid-Rich Diet on Plasma Profiles of Eicosanoids and Development of Colitis in Il-10-/- Mice, J. Ag. Food Chem. 68: 7641-7647. 

  9. R. Farias-Pereira, C.-S. Park, and Y. Park (2020) Kahweol reduces food intake of Caenorhabditis elegans, J. Ag. Food Chem. 68: 9683-9689. 

  10. P. B. Chen, L. Young, J. H. Kim, W. Qi, J. M. Clark, and Y. Park (2020) Conjugated Linoleic Acid (CLA) Regulates Female Reproduction via Sex Pheromone Regulation Without Affecting Larval Development in Drosophila melanogaster, Food Life 2020: 37-45. 

  11. J. S. Yang, J. Tongson, K.-H. Kim, and Y. Park (2020) Piceatannol Attenuates Fat Accumulation and Oxidative Stress in Steatosis-Induced HepG2 Cells, Current Res. Food Sci. 3: 92-99. 

  12. R. Farias-Pereira, J. Savarese, Y. Yue, S.-H. Lee, and Y. Park (2020) Fat-Lowering Effects of Isorhamnetin via NHR-49-Dependent pathway in Caenorhabditis elegans, Curr. Res. Food Sci. 2: 70-76. 

  13. R. Farias-Pereira, E. Kim, and Y. Park (2020) Cafestol Increases Fat Oxidation and Energy Expenditure in Caenorhabditis elegans via DAF-12-Dependent Pathway, Food Chem. 307: 125537. 

2019 

  1. J. Zhang, X. Chen, R. Yang, Q. Ma, W. Qi, K. Z. Sanidad, Y. Park, D. Kim, E. A. Decker and G. Zhang (2019) Thermally Processed Oil Exaggerates Colonic Inflammation and Colitis-Associated Colon Tumorigenesis in Mice, Cancer Prev. Res. 12: 741-750. 

  2. P. B. Chen, J. H. Kim, L. Young, J. M. Clark, and Y. Park (2019) Epigallocatechin gallate (EGCG) Alters Body Fat and Lean Mass Through Sex-Dependent Metabolic Mechanisms in Drosophila melanogaster, Int. J. Food Sci. Nutr. 70: 959-969. 

  3. R. Farias-Pereira, C.-S. Park, and Y. Park (2019) Mechanisms of Action of Coffee Bioactive Components on Lipid Metabolism, Food Sci. Biotech. 28: 1287-1296. 

  4. L. Yuan, J. Lin, Y. Xu, Y. Peng, J. M. Clark, R. Gao, Y. Park, and Q. Sun (2019) Deltamethrin Promotes Adipogenesis via AMPKα and ER Stress-Mediated Pathway in 3T3-L1 Adipocytes and Caenorhabditis elegans, Food Chem. Tox. 139: 110791. 

  5. Y. Peng, Q. Sun, and Y. Park (2019) The Bioactive Effects of Chicoric Acid as a Functional Food Ingredient, J. Med. Food 22: 645-652. 

  6. Y. Peng, Q. Sun, R. Gao, and Y. Park (2019) AAK-2 and SKN-1 Are Involved in Chicoric Acid-Induced Lifespan Extension in Caenorhabditis elegans, J. Ag. Food Chem. 67: 9178-9186. 

  7. Y. Yue, P. Shen, A. L. Chang, W. Qi, K.-H. Kim, and Y. Park (2019) trans-Trismethoxy Resveratrol Decreased Fat Accumulation Dependent on fat-6 and fat-7 in Caenorhabditis elegans, Food Func. 10: 4966-4974. 

  8. W. Qi, J. M. Clark, and Y. Park (2019) Ivermectin Decreased Triglyceride Accumulation by Inhibiting Differentiation of 3T3-L1 Preadipocytes, Food Chem. Tox. 131: 110576. 

  9. Y. Peng, Q. Sun, and Y. Park, (2019) Chicoric Acid Promotes Glucose Uptake and Akt Phosphorylation via AMPK-Activated Protein Kinase a-Dependent Pathway, J. Func. Food 59: 8-15.  

  10. Y. Yue, P. Shen, Y. Xu, and Y. Park (2019) p-Coumaric Acid Improves Oxidative and Osmosis Stress Responses in Caenorhabditis elegans, J. Sci. Food and Ag. 99: 1190-1197. 

  11. J. S. Yang, W. Qi, S. Choi, J. M. Clark, D. Kim, and Y. Park (2019) Permethrin and Ivermectin Modulate Lipid Metabolism in Steatosis-Induced HepG2 Hepatocyte, Food Chem. Tox. 125: 595-604. PMCID: PMC6527113 

  12. P. Shen, R. Zhang, D. J. McClements, and Y. Park (2019) Nanoemulsion-Based Delivery Systems for Testing Nutraceutical Efficacy Using Caenorhabditis elegans: Demonstration of Curcumin Bioaccumulation and Body-Fat Reduction, Food Res. Int. 120: 157-160. 

2018 

  1. Y. Xu and Y. Park (2018) Application of Caenorhabditis elegans for Research on Endoplasmic Reticulum Stress, Prev. Nutr. Food Sci. 23: 275-281. 

  2. P. B. Chen, J. H. Kim, D. Kim, J. M. Clark, and Y. Park (2018) Conjugated Linoleic Acid (CLA) Regulates Body Composition and Locomotor Activity in Sex-Dependent Manners in Drosophila melanogaster, Lipids 53: 825-834. 

  3. J. Liu, Y. Peng, Y. Yue, P. Shen, and Y. Park (2018) Epigallocatechin-3-Gallate Reduces Fat Accumulation in Caenorhabditis elegans, Prev. Nutr. Food Sci. 23: 214-219. 

  4. J. S. Yang, and Y. Park (2018) Insecticide Exposure and Development of Non-Alcoholic Fatty Liver Disease, J. Ag. Food Chem. 66: 10132-10138. 

  5. J. S. Yang, S. Symington, J. M. Clark, and Y. Park (2018) Permethrin, a Pyrethroid Insecticide, Regulates ERK1/2 Activation Through Membrane Depolarization-Mediated Pathway in HepG2 Hepatocytes, Food Chem. Tox. 121: 387-395. PMCID:PMC6235143 

  6. W. Qi, J. M. Clark, A. R. Timme-Laragy, and Y. Park (2018) Perfluorobutanesulfonic Acid (PFBS) Potentiates Adipogenesis of 3T3-L1 Adipocytes, Food Chem. Tox. 120: 340-345. PMCID:PMC6169790 

  7. R. Farias-Pereira, J. Oshiro, K.-H. Kim, and Y. Park (2018) Green Coffee Bean Extract and 5-O-Caffeoylquinic Acid Regulate Fat Metabolism in Caenorhabditis elegans, J. Func. Foods. 48: 586-593. 

  8. W. Wang, J. Yang, J. Zhang, Y. Wang, S. H. Hwang, W. Qi, D. Wan, D. Kim, J. Sun, K. Sanidad, H. Yang, Y. Park, J.-Y. Liu, X. Zhao, X. Zheng, Z. Liu, B.D. Hammock, and G. Zhang (2018) Lipidomic Profiling Reveals Soluble Epoxide Hydrolase as a Therapeutic Target of Obesity-Induced Colonic Inflammation, Proc. Nat. Acad Sci. USA. 115: 5283-5288. 

  9. F. Etemadi, A. V. Barker, M. Hashemi, O. R. Zandvakili, and Y. Park (2018) Nutrient Accumulation in Faba Bean Varieties, Comm. Soil Sci. Plant Anal. 49: 2064-2073. 

  10. P. B. Chen, S.-H. Yang, and Y. Park (2018) Adaptations of Skeletal Muscle Mitochondria to Obesity, Exercise, and Polyunsaturated Fatty Acids, Lipids 53: 271-278. 

  11. P. Shen, Y. Yue, J. Zheng, and Y. Park (2018) Caenorhabditis elegans: A Convenient In Vivo Model for Assessing the Impact of Food Bioactive Components on Obesity, Aging, and Alzheimer’s Disease, Ann. Rev. Food Sci. Tech. 9: 1-22. 

  12. P. Shen, Y. Yue, and Y. Park (2018) A Living Model for Obesity and Aging Research: Caenorhabditis elegans, Crit. Rev. Food Sci. Nutr. 58: 741-754. 

  13. Z. Ma, A. Garrido-Maestu, C. Lee, J. Chon, D. Jeong, Y. Yue, K. Sung, Y. Park, and KC. Jeong (2018) Comprehensive In Vitro and In Vivo Evaluation of Chitosan Microparticles for Risk Assessments Using Epithelial Cells and Caenorhabditis elegans, J. Hazard. Mat. 342: 248-256. 

  14. X. Xiao, Q. Sun, Y. Kim, S.-H. Yang, W. Qi, D. Kim, K. S. Yoon, J. M. Clark, and Y. Park (2018) Exposure to Permethrin Promotes High Fat Diet-Induced Weight Gain and Insulin Resistance Male C57BL/6J Mice, Food Chem. Tox. 111: 405-416. PMCID: PMC5756676 

  15. P. Shen, Y. Yue, J. C. Kershaw, O. Wang, K.-H. Kim, D. J. McClements, and Y. Park (2018) Effects of Conjugated Linoleic Acid (CLA) on Fat Accumulation, Activity, and Proteomics Analysis in Caenorhabditis elegans, Food Chem. 249: 193-201. 

2017 

  1. Q. Sun, J. M. Clark, and Y. Park (2017) Environmental Pollutants and Type 2 Diabetes: A Review of Human Studies, Tox. Env. Chem. 99: 1283-1303. 

  2. P. Shen, Y. Yue, K.-H. Kim, and Y. Park (2017) Piceatannol Reduces Fat Accumulation in Caenorhabditis elegans, J. Med. Food 20: 887-894. 

  3. R. Zhang, W. Wu, Z. Shang, Y. Park, L. He, X. Baoshan, and D. J. McClements (2017) Effect of the Composition and Structure of Excipient Emulsion on the Bioaccessibility of Pesticides Residue in Agricultural Products, J. Ag. Food Chem. 65: 9128-9218. 

  4. J. Kim, M. Y. Park, Y. Kim, K. S. Yoon, J. M. Clark, Y. Park, and K.-Y. Whang (2017) 4,4’-Dichlorodiphenyltrichloroethane (DDT) and 4,4’-Dichlorodiphenyldichloroethylene (DDE) Inhibit Myogenesis in C2C12 Myoblasts, J. Sci. Food Ag. 97: 5176-5185. 

  5. Q. Sun, Y. Peng, W. Qi, J. M. Clark, and Y. Park (2017) Permethrin-Induced Insulin Resistance is Dependent on Extracellular Signal-Regulated Kinase -1 (ERK), but Not AMP-Activated Protein Kinase (AMPK) in C2C12 Myotubes, Food Chem. Tox. 109: 95-101. 

  6. X. Xiao, J. M. Clark, and Y. Park (2017) Permethrin Potentiates Adipogenesis via Intracellular Calcium and Endoplasmic Reticulum Stress-Mediated Mechanisms in 3T3-L1 Adipocytes, Food Chem. Tox. 109: 123-129. 

  7. Q. Sun, W. Qi, X. Xiao, S.-H. Yang, D. Kim, K. S. Yoon, J. M. Clark, and Y. Park (2017) Imidacloprid Promotes High Fat Diet-Induced Adiposity in Female C57BL/6J Mice and Enhance Adipogenesis in 3T3-L1 Adipocytes via AMPKa-Mediated Pathway, J. Ag. Food Chem. 65: 6572-6581. PMCID:PMC5576855   

  8. X. Xiao, Y. Kim, D. Kim, K. S. Yoon, J. M. Clark, and Y. Park (2017) Permethrin Alters Glucose Metabolism in Conjunction with High Fat Diet by Potentiating Insulin Resistance and Decreases Voluntary Activities in Female C57BL/6J Mice, Food Chem. Tox. 108: 161-170. PMCID:PMC5588858 

  9. E. Jahanzad, A. V. Barker, M. Hashemi, A. Sadeghpour, T. Eaton, and Y. Park (2017) Improving Yield and Mineral Nutrient Concentration of Potato Tubers Through Cover Cropping, Field Crops Res. 212: 45-51. 

  10. J. Lee, Y. Yue, Y. Park, and S.-H. Lee (2017) 3,3'-Diindolylmethane Suppresses Adipogenesis via AMPK-Dependent Mechanism in 3T3-L1 Adipocytes and Caenorhabditis elegans, J. Med. Food 20: 646-652.  

  11. W. Wang, J. Yang, Y. Nimiya, K. S. S. Lee, K. Sanidad, W. Qi, E. Sukamtoh, Y. Park, Z. Liu, and G. Zhang (2017) w-3 Polyunsaturated Fatty Acids and Their Cytochrome P540-Derived Metabolites Suppress Colorectal Tumor Development in Mice, J. Nutr. Biochem. 48: 29-35. 

  12. P. Shen, Y. Yue, Q. Sun, N. Kasireddy, K.-H. Kim, and Y. Park (2017) Piceatannol Extends the Lifespan of Caenorhabditis elegans Via DAF-16, Biofactors, 43: 379-387. 

  13. X. Xiao, J. M. Clark, and Y. Park (2017) Potential Contribution of Insecticide Exposure and Development of Obesity and Type 2 Diabetes, Food Chem. Tox. 105: 456-474. PMCID:PMC5518693 

  14. S. J. Hur, H. S. Kim, Y. Y. Bahk, and Y. Park (2017) Overview of Conjugated Linoleic Acid Formation and Accumulation in Animal Products, Livestock Sci. 195: 105-111.  

  15. L. Salvia-Trujillo, B. Fumiaki, Y. Park, and D. J. McClements (2017) Influence of Lipid Droplet Size on the Oral Bioavailability of Vitamin D2 Encapsulated in Emulsions: An In Vitro and In Vivo Study, Food Func. 8: 767-777. 

  16. Z. Zhang, R. Zhang, Q. Sun, Y. Park, and D. J. McClements (2017) Confocal Fluorescence Mapping of pH Profile Inside Hydrogel Beads (Microgels) with Controllable Internal pH Values, Food Hydrocolloids 65: 198-205. 

  17. P. Shen, T.-H. Hsieh, Y. Yue, Q. Sun, J. M. Clark, and Y. Park (2017) Deltamethrin Increases the Fat Accumulation in 3T3-L1 Adipocytes and Caenorhabditis elegans, Food Chem. Tox. 101: 149-156. 

  18. W. Wang, J. Yang, W. Qi, H. Yang, C. Wang, B. Tan, B. D. Hammock, Y. Park, D. Kim, and G. Zhang (2017) Lipidomic Profiling of High-Fat Diet-Induced Obesity in Mice: Importance of Cytochrome P450-Derived Fatty Acid Epoxides, Obesity 25: 132-140. 

2016 

  1. Q. Sun, X. Xiao, Y. Kim, D. Kim, K. S. Yoon, J. M. Clark, and Y. Park (2016) Imidacloprid Promotes High Fat Diet-Induced Adiposity and Insulin Resistance in Male C57BL/6J Mice, J. Ag. Food Chem. 64: 9293-9306. PMCID:PMC5325319 

  2. J. Kim, M. Y. Park, H. K. Kim, Y. Park, and K.-Y. Whang (2016) Cortisone and Dexamethasone Inhibit C2C12 Myogenesis by Modulating AKT and mTor Signaling Pathway, Biosci. Biotech. Biochem. 80: 2093-2099. DOI: 10.1080/09168451.2016.1210502 

  3. Y. Kim and Y. Park (2016) Conjugated Linoleic Acid (CLA) Promotes Endurance Capacity Via Peroxisome Proliferator-Activated Receptor δ-Mediated Mechanism in Mice, J. Nutr. Biochem. 38: 125-133. 

  4. Y. Kim, D. J. Good, and Y. Park (2016) Conjugated Linoleic Acid (CLA) Improves Muscle Metabolism via Stimulating Mitochondrial Biogenesis Signaling in Genetically Induced Inactive Adult-Onset Obese Mice, Eur. J. Lipid Sci. Tech. 118: 1305-1316. 

  5. H. M. Abdulla, P. Akabari, B. Paulose, D. Schnell, W. Qi, Y. Park, A. Pareek, and O. P. Dhankher (2016) Transcriptome Profiling of Camelina sativa to Identify Genes Involved in Triacylglycerol Biosynthesis and Accumulation in the Developing Seeds, Biotech. Biofuels. 9: 136. 

  6. J. Kim, Q. Sun, Y. Yue, K. S. Yoon, K.-Y. Whang, J. M. Clark, and Y. Park (2016) 4,4’-Dichlorodiphenyltrichloroethane (DDT) and 4,4’-Dichlorodiphenyldichloroethylene (DDE) Promote Adipogenesis in 3T3-L1 Adipocyte Cell Culture, Pesticide Biochem. Phys. 131: 40-45. 

  7. Q. Sun, W. Qi, J. J. Yang, K. S. Yoon, J. M. Clark, and Y. Park (2016) Fipronil Promotes Adipogenesis Via AMPKα-Mediated Pathway in 3T3-L1 Adipocytes, Food Chem. Tox. 92: 217-223. 

  8. Q. Sun, Y. Yue, P. Shen, J. J. Yang, and Y. Park (2016) Cranberry Bioactives Decrease Fat Accumulation in C. elegans, J. Med. Food. 19: 427-433. 

  9. J. H. Kim, Y. Kim, Y. J. Kim and Y. Park (2016) Conjugated Linoleic Acid-Potential Health Benefits as a Functional Food Ingredient, Ann. Rev. Food Sci. Tech. 7:221-244. 

  10. L. Cui, H. T. Cho, D. J. McClements, E. A. Decker, and Y. Park (2016) Effects of salts on oxidative stability of lipids in oil-in-water emulsion, Food Chem. 197: 1130-1135. 

  11. D. Colmenares, Q. Sun, P. Shen, Y. Yue, D. J. McClements, and Y. Park (2016) Delivery of Dietary Triglycerides to Caernohabditis elegans Using Lipid Nanoparticles: Nanoemulsion-Based Delivery Systems, Food Chem. 202: 451-457. 

  12. Y. Kim, J. Kim, K.-Y. Whang, and Y. Park (2016) Impact of Conjugated Linoleic Acid (CLA) on Skeletal Muscle Metabolism, Lipids 51: 159-178. 

2015 

  1. Y. Kim, D. Kim, D. J. Good, and Y. Park (2015) Effects of Post-Weaning Administration of Conjugated Linoleic Acid on Development of Obesity in Nescient Basic Helix-Loop-Helix 2 Knockout Mice, J. Ag. Food Chem. 63: 5212-5223. 

  2. L. Salvia-Trujillo, Q. Sun, B.-H. Um, Y. Park, and D. J. McClements (2015) In Vitro and In Vivo Study of Fucoxanthin Bioavailability From Nanoemulsion-Based Delivery Systems: Impact of Lipid Carrier type, J. Func. Foods 17: 293-304.  

  3. J. H. Kim, Y. J. Kim, and Y. Park (2015) Conjugated Linoleic Acid and Postmenopausal Women’s Health, J. Food Sci. 80:R1137-R1143. 

  4. Y. Kim and Y. Park (2015) Conjugated Linoleic Acid (CLA) Stimulates Mitochondrial Biogenesis Signaling by the Upregulation of Peroxisome Proliferator-Activated Receptor- γ Coactivator 1α in C2C12 Cells, Lipids 50: 329-338. 

  5. J. Wong, Y. Kim, YH. Park, S.-H. Lee, S. J. Baek, and Y. Park (2015) Isomer Specificity of Conjugated Linoleic Acid on Suppression of Osteosarcomas, J. Nature Sci. 1: e67. 

  6. X. Xiao, J. Kim, Q. Sun, D. Kim, C.-S. Park, T.-S. Lu, and Y. Park (2015) Preventive Effects of Cranberry Products on Experimental Colitis Induced by Dextran Sulfate Sodium in Mice, Food Chem. 167: 438-446. 

  7. K.-J. Kim, J. Lee, Y. Park, and S.-H. Lee (2015) ATF3 Mediates Anti-Cancer Activity of trans-10, cis-12-Conjugated Linoleic Acid in Human Colon Cancer Cells, Biomol. Therap. 23: 134-140. 

2014 

  1. J. Kim, YH Park, K. S. Yoon, J. M. Clark, and Y. Park (2014) Permethrin alters adipogenesis in 3T3-L1 adipocytes and causes insulin resistance in C2C12 myotubes, J. Biochem. Mol. Tox. 28:418-424. 

  2. M. Lahlou, R. Kanneganti, L. J. Massingill, G. A. Broderic, Y. Park, M. W. Pariza, J. D. Ferguson, and Z. Wu (2014) Grazing Increases the Concentration of Conjugated Linoleic Acid in Milk of Dairy Cows, Animal: Int. J. Animal Biosci. 8:1091-1200. 

  3. J. Kim, YH. Park, and Y. Park (2014) trans-10,cis-12 Conjugated Linoleic Acid Promotes Osteoblastogenesis via SMAD Mediated Mechanism in Bone Marrow Mesenchymal Stem Cells, J. Func. Foods 8:367-376. PMCID: PMC4095819 

  4. H. T. Cho, L. Salvia-Trujillo, J. Kim, Y. Park, H. Xiao, and D. J. McClements (2014) Influence of Droplet Size and Composition on Bioavailability of Long Chain Fatty Acids and Coenzyme Q10: An In Vivo Study, Food Chem. 156:117-122. 

2013 

  1. J. Kim, YH. Park, K. S. Yoon, J. M. Clark, and Y. Park (2013) Imidacloprid, a neonicotinoid insecticide, induces insulin resistance, J. Toxicol. Sci. 38: 655-660. 

  2. YH. Park, Y. Kim, K. S. Yoon, J. Kim, J. M. Clark, J. Lee, and Y. Park (2013) A Neonicotinoid Insecticide, Imidacloprid, Potentiates Lipid Accumulation in 3T3-L1 Adipocytes, J. Agric. Food Chem. 61:255-259. 

  3. YH. Park, J. Kim, A. G. Scrimgeour, M. L. Condlin, D. Kim and Y. Park (2013) Conjugated Linoleic Acid and Calcium Co-Supplementation Improves Bone Health in Ovariectomized Mice, Food Chem. 140:280-288. PMCID: PMC3625250 

  4. J. H. Kim, YH. Park, D. Kim, D. J. Good, and Y. Park (2013) Dietary Conjugated Nonadecadienoic Acid Prevents Adult-Onset Obesity in Nescient Basic Helix-Loop-Helix 2 Knockout Mice, J. Nutr. Biochem. 24:556-566. 

  5. J. Kim, YH. Park, S.-H. Lee, and Y. Park (2013) trans-10,cis-12 Conjugated Linoleic Acid Promotes Bone Formation by Inhibiting Adipogenesis by Peroxisome Proliferator Activated Receptor-γ Dependent Mechanisms and by Directly Enhancing Osteoblastogenesis From Bone Marrow Mesenchymal Stem Cells, J. Nutr. Biochem. 24:672-679. PMCID: PMC3482420 

2012 

  1. J. H. Kim, D. Gilliard, D. J. Good, and Y. Park (2012) Preventive Effects of Conjugated Linoleic Acid on Obesity by Improved Physical Activity in Nescient Basic Helix-Loop-Helix 2 Knockout Mice During Growth Period, Food Function 3:1280-1285. 

  2. Y. Li, J. Kim, Y. Park, and D. J. McClements (2012) Modulation of Lipid Digestibility using Structured Emulsion-Based Delivery Systems: Comparison of in vivo and in vitro Measurements, Food Function 3:528-536. 

  3. J. H. Kim, J. Kim, and Y. Park (2012) trans-10,cis-12 Conjugated Linoleic Acid Enhances Endurance Capacity by Increasing Fatty Acid Oxidation and Reducing Glycogen Utilization in Mice, Lipids 47: 855-863. 

  4. J. H. Kim, YH. Park, D. Kim, and Y. Park (2012) Dietary Influences on Physical Activity and Energy Expenditure in C57BL/6J Mice, J. Food Sci. 77:H63-H68. 

  5. A. Dilzer, and Y. Park (2012) Implication of Conjugated Linoleic Acid (CLA) in Human Health, Crit. Rev. Food Sci. Nutr. 52: 488-513. 

  6. YH. Park, and Y. Park (2012) Conjugated Fatty Acids Increase Energy Expenditure by Increasing Voluntary Movement in Mice, Food Chem. 133: 400-409. 

2011 

  1. YH. Park, M. Terk, and Y. Park (2011) Interaction between Dietary Conjugated Linoleic Acid (CLA) and Calcium Supplementation on Bone and Fat Mass, J. Bone Miner. Meta. 29: 268-278. 

  2. K.-H. Kim, and Y. Park (2011) Food Components with Anti-Obesity Effects, Ann. Rev. Food Sci. Tech. 2: 237-257. 

2010 

  1. YH. Park, and Y. Park (2010) Conjugated Nonadecadienoic Acid is More Potent Than Conjugated Linoleic Acid on Body Fat Reduction, J. Nutr. Biochem. 21: 764-773. 

  2. E. A. Decker, and Y. Park (2010) Healthier meat products as functional food, Meat Science 86: 49-55.  

  3. Y. Park, K. J. Albright, J. M. Storkson, W. Liu, and M. W. Pariza (2010) Effects of Dietary Conjugated Linoleic Acid (CLA) on Spontaneously Hypertensive Rats, J. Functional Foods 2: 54-59. 

2009 

  1. Y. Park (2009) Conjugated Linoleic Acid (CLA): Good or bad trans fat? J. Food Comp. Anal. 22S: S4-S12.  

  2. Y. Park, and M. W. Pariza (2009) Bioactivities and Potential Mechanisms of Action for Conjugated Fatty Acids, Food Sci. Biotech. 18: 586-593. 

  3. D. J. McClements, E. A. Decker, Y. Park, and J. Weiss (2009) Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods, Crit. Rev. Food Sci. Nutr. 49: 577-606. 

  4. S. J. Hur, F. Whitcomb, S. Rhee, YH. Park, D. J. Good, and Y. Park (2009) Effects of trans-10,cis-12 Conjugated Linoleic Acid on Body Composition in Genetically Obese Mice, J. Med. Food 12: 56-63. 

  5. D. J. McClements, E. A. Decker, and Y. Park (2009) Controlling Lipid Bioavailability through Physicochemical and Structural Approaches, Crit. Rev. Food Sci. Nutr. 49: 48-67. 

2008 

  1. YH. Park, M. W. Pariza, and Y. Park (2008) Co-supplementation of Dietary Calcium and Conjugated Linoleic Acid (CLA) Improves Bone Mass in Mice, J. Food Sci. 73: C556-C560. 

  2. D. J. McClements, E. A. Decker, Y. Park, and J. Weiss (2008) Designing food structure to control stability, digestion, release and absorption of lipophilic food components, Food Biophysics 3: 219-228.  

  3. S. Mahadevan, YH. Park, and Y. Park (2008) Modulation of Cholesterol Metabolism by Ginkgo biloba L. Nuts and their Extract, Food Res. Int. 41: 89-95. 

  4. S. Mahadevan, and Y. Park (2008) Multifaceted Therapeutic Benefits of Ginkgo biloba L.: Chemistry, Efficacy, Safety and Uses, J. Food Sci. 73: R14-19. 

2007 

  1. Y. Park, K. J. Albright, J. M. Storkson, W. Liu, YH. Park, and M. W. Pariza (2007) Influence of Stearidonic Acid on Lipoprotein Secretion and Fatty Acid Composition in HepG2 Cells, J. Food Lipids 14: 366-376.  

  2. Y. Park, K. J. Albright, J. M. Storkson, W. Liu, and M. W. Pariza (2007) Conjugated Linoleic Acid (CLA) Prevents Body Fat and Weight Gain in an Animal Model, J. Food Sci. 72: S612-S617. 

  3. S. J. Hur and Y. Park (2007) Effects of Conjugated Linoleic Acid on Bone Formation and Rheumatoid Arthritis, Eur. J. Pharmacol. 568: 16-24. 

  4. G. Y. Park, S. Mun, YH. Park, S. Rhee, E. A. Decker, J. Weiss, D. J. McClements, and Y. Park (2007) Influence of Encapsulation of Emulsified Lipids with Chitosan on their In Vivo Digestibility, Food Chem. 104: 761-767. 

  5. Y. Park, M. Yang, J. M. Storkson, K. J. Albright, W. Liu, M. E. Cook, and M. W. Pariza (2007) Effects of Conjugated Linoleic Acid (CLA) Isomers on Serum Tumor Necrosis Factor-α Concentration in Mice, J. Food Biochem. 31: 252-265. 

  6. Y. Park, and M. W. Pariza (2007) Mechanisms of Body Fat Modulation by Conjugated Linoleic Acid (CLA), Food Res. Int. 40: 311-323. 

  7. Y. Park, Y. L. Ha, and M. W. Pariza (2007) π-Complex Formation of Conjugated Linoleic Acid (CLA) with Iron, Food Chem. 100: 972-976. 

2006 

  1. G. Li, D. Butz, B. Dong, Y. Park, M. W. Pariza, and M. E. Cook (2006) Selective Conjugated Fatty Acids Inhibit Guinea Pig Platelet Aggregation, Eur. J. Pharmacol. 545: 93-99.  

  2. G. Li, B. Dong, D. E. Butz, Y. Park, M. W. Pariza, and M. E. Cook (2006) NF-κB Independent Inhibition of Lipopolysaccharide-Induced Cyclooxygenase by a Conjugated Linoleic Acid Cognate, Biochim. Biophys. Acta 1761: 969-972. 

  3. S.-H. Lee, K. Yamaguchi, J.-S. Kim, T. E. Eling, Y. Park, and S. J. Baek (2006) Conjugated Linoleic Acid Stimulates an Anti-Tumorigenic Protein NAG-1 in an Isomer Specific Manner, Carcinogenesis 27: 972-981. 

  4. S. Mun, E. A. Decker, Y. Park, J. Weiss, and D. J. McClements (2006) Influence of Interfacial Composition on In Vitro Digestibility of Emulsified Lipids: Potential Mechanisms for Chitosan’s Ability to Inhibit Fat Absorption, Food Biophysics 1:21-29. 

2005 

  1. Y. Park, K. J. Albright, and M. W. Pariza (2005) Effects of Conjugated Linoleic Acid on Long Term Feeding in Fischer 344 Rats, Food Chem. Tox. 43: 1273-1279. 

  2. J. M. Storkson, Y. Park, M. E. Cook, and M. W. Pariza (2005), Effects of trans-10,cis-12 Conjugated Linoleic Acid (CLA) on Cognates on Apolipoprotein B Secretion in HepG2 Cells, Nutr. Res. 25: 387-399. 

  3. Y. Park, J. M. Storkson, K. J. Albright, W. Liu, and M. W. Pariza (2005) Biological Activities of Conjugated Fatty Acids: Conjugated Eicosadienoic (conj. 20:2Δc11,t13/ t12,c14), Eicosatrienoic (conj. 20:3Δc8,t12,c14), and Heneicosadienoic (conj. 21:2Δc12,t14/ c13,t15) Acids and Other Metabolites of Conjugated Linoleic Acid, Biochim. Biophys. Acta 1687: 120-129.