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Luke’s current research aims to address why the skeletal muscle of older adults may acidify less than younger adults during fatiguing contractile activity. Skeletal muscle acidosis has previously been shown to be related to fatigue, but the exact mechanisms driving the age-related differences in acidosis are not yet known. Several proposed mechanisms have been suggested, such as the availability of oxygen and glycogen, but there has yet to be a comprehensive assessment to understand the age-related differences in acidosis. Luke’s assessment will identify any cumulative or interactive effects of each mechanism on acidosis and further our understanding of age-related fatigue mechanisms.