University of Massachusetts Amherst

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Jungwoo Lee

Jungwoo Lee
Associate Professor, Department of Chemical Engineering


School or College: 

College of Engineering


Dr. Jungwoo Lee, Associate Professor in the Department of Chemical Engineering, earned his B.E. in Chemical Engineering from Korea University and his Ph.D. in Biomedical Engineering from the University of Michigan-Ann Arbor. After completing his postdoctoral training at Massachusetts General Hospital, Dr. Lee began focusing his research on bone marrow tissue engineering and cancer metastasis. He has received numerous accolades, including the Junior Faculty Award from the College of Engineering at UMass-Amherst, the President Young Investigator Award from the Korean Institute of Chemical Engineers, the Early Career Investigator Award from the METAvivor Foundation, the Career Award from the National Science Foundation, and the Pathway to Independence Award from the National Institutes of Health.

Research Proposal Title: 

Bioengineered 3D Human Bone and Marrow Mechanoculture Models to promote Healthy Skeletal Aging and Metastasis-free Survivorship


Dr. Lee's research is centered on developing bioengineered bone marrow where bone and blood biology are functionally integrated, for basic and translational research purposes. These models strive to facilitate a comprehensive understanding of bone marrow development, aging, and metastasis, ultimately leading to targeted anti-aging and anti-metastasis pharmacological strategies. The successful creation of humanized bone and marrow models holds significant potential for impacting bone marrow transplantation and living bone grafts. To reproduce the unique complexity of bone marrow, which consists of the hardest (bone) and softest (marrow) tissues, Dr. Lee employs advanced biomaterials, stem cell biology, and various mechanoculture techniques. This approach enables him to replicate the biophysical and biochemical intricacies of the human body in microphysiological bone marrow tissue models. Dr. Lee aims to establish, validate, and apply human bone marrow models in the realms of aging and cancer research.