Amy Schalet's research has focused on sexuality and culture. She has authored several publications on comparative adolescent sexuality. Her book Raging Hormones, Regulated Love, to be published by the University of Chicago Press, examines approaches to adolescent sexuality in American and Dutch middle-class families. Prior to coming to the University of Massachusetts Amherst, Dr. Schalet held a three-year postdoctoral fellowship at the School of Medicine at the University of California, San Francisco, where she pursued the public health and policy implications of her research on adolescent sexual health.

Dr. Schalet has given plenary addresses at several public health conferences, including the CDC Conference on STD-Prevention. She was recently awarded a grant by the Ford Foundation entitled, "Advancing Sexuality Education, Health and Policy Using a New ABCD for Adolescent Sexuality" which will expand previous work with physicians to educators, administrators, and school-based nurses.