Aging, Lysosomes, and Neurodegenerative Disease

Neurodegenerative diseases, such as Alzheimer's and Parkinson's are incurable and debilitating conditions that result in progressive degeneration and / or death of nerve cells. Dr. Kao's work suggests that not only are lysosomes key players in neurodegenerative disease pathogenesis, but that they can be targeted for therapeutic intervention. She will discuss the different ways that protein degradation via the autophagy lysosome pathway can be disturbed in neurodegenerative disease. She will cover recent insights into tauopathy...