( A B C D F G H J K L M N P R S T V W X Y Z

Please select the first letter of the last name you are looking for.

Yossi Chait


My research interests lie at the interface of engineering, mathematics, and medicine. 

Current Research

My current research is focused in developing personalized diagnostic and treatment protocols in end-stage kidney disease: (1) anemia management protocols based on a mathematical model of erythropoiesis, (2) absolute blood volume measurement during hemodialysis based on advanced intravascular blood kinetic model, (3) optimal ultrafiltration profiles with individualized hemodynamic targets, and (4) non-invasive measurement of hemodynamic parameters during hemodialysis.

Learn more at

Academic Background

  • B.S The Ohio State University, Columbus 1982
  • M.S Michigan State University, East Lansing 1984
  • PH.D. Michigan State University, East Lansing 1988
Chait Y, Kalim S, Horowitz J, Hollot CV, Ankers ED, Germain MJ, Thadhani RI. The greatly misunderstood erythropoietin resistance index and the case for a new responsiveness measure. Hemodial Int. 2016 20(3):392-8, PMID: 26843352.
Shrestha RP, Horowitz J, Hollot CV, Germain MJ, Widness JA, Mock DM, Veng-Pedersen P, Chait Y. Models for the red blood cell lifespan. J Pharmacokinet Pharmacodyn. 2016 Jun;43(3):259-74, PMID: 27039311.
Gaweda AE, Ginzburg YZ, Chait Y, Germain MJ, Aronoff GR, Rachmilewitz E. Iron dosing in kidney disease: inconsistency of evidence and clinical practice. Nephrol Dial Transplant. 2015 30(2):187-9, PMID: 24821751.
Chait Y, Horowitz J, Nichols B, Shrestha RP, Hollot CV, Germain MJ. Control-relevant erythropoiesis modeling in end-stage renal disease. IEEE Trans Biomed Eng. 2014 61(3):658-64, PMID: 24235247.
Merrill S, Horowitz J, Traino AC, Chipkin SR, Hollot CV, Chait Y. Accuracy and optimal timing of activity measurements in estimating the absorbed dose of radioiodine in the treatment of Graves' disease. Phys Med Biol. 2011 56(3): 557-71, PMID: 21212469
Degon M, Chipkin SR, Hollot CV, Zoeller RT, Chait Y. A Mathematical Model of the Human Thyroid, Mathematical Biosciences, 2008 212(1):22-53, PMID: 18291425.
Contact Info

Mechanical and Industrial Engineering
ELAB 1 208d
160 Governors Drive
Amherst, MA 01003-9292

(413) 545-0134