Yahya Modarres-Sadeghi

At the FSI Lab, we use experimental, theoretical and numerical tools to understand different Fluid-Structure Interaction phenomena both from a fundamental point of view and with applications in several fields including biomedical science. An example is the problem of cerebral aneurysms. Cerebral aneurysms are the dilation of part of the wall of an artery in the brain. They can occur at any age, their formation is multifactorial and results from the interplay between a biological process in the arterial wall and hemodynamic forces and stimuli which act on the wall. Repetitive forces on an existing aneurysm can lead either to its gradual expansion or to a sudden rupture, the latter causing a severely disabling and sometimes devastating or fatal intracranial hemorrhage. The artery, the aneurysm attached to it and the pulsatile blood flow inside the artery constitute an FSI problem with flexible structures – arteries and the aneurysm – in contact with pulsatile blood flow. We use advanced FSI modeling tools to derive reduced order models, which can be used to predict the rate of growth and the risk of rupture of cerebral aneurysms.