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Seth Donahue


Developing new tissue engineering strategies for bone regeneration by utilizing innovative biomaterials to deliver stem cells and gene therapy to large bone defects.

Current Research

Hydrogel delivery of mesenchymal stem cells for bone regeneration. Collagen scaffold delivery of microRNA or bone regeneration. Bioinspired design for 3D printing. The Donahue lab studies the biology, physiology, and mechanics of bone from animals that have adapted to extreme environmental conditions. Examples include Trinidadian guppies, little pocket mice, arctic ground squirrels, bighorn sheep, hibernating bears, and dinosaurs. We also use more traditional laboratory rodent models to study treatments for osteoporosis and tissue engineering approaches to regenerating new bone tissue.

Learn more: https://www.umass.edu/engineering/about/directory/seth-donahue

Learn more: The Donahue Lab

Complete list of published works: https://scholar.google.com/citations?user=5qyCWDMAAAAJ&hl=en

Academic Background

  • BS 1992, Worcester Polytechnic Institute - Mechanical Engineering
  • MS 1997, University of California, Davis - Biomedical Engineering
  • PhD 1999, University of California, Davis - Biomedical Engineering
  • Post-Doc 2001, Pennsylvania State University Medical Center - Orthopaedics
Contact Info

Biomedical Engineering
LSL 625
240 Thatcher Road
Amherst, MA 01003-9292

Office: (413) 545-6366
Email: swdonahue@umass.edu