Our laboratory investigates circulating and resident cell types that have angiogenic potential including hematopoietic stem cells, monocytes, fibroblasts, and pericytes.
These cells communicate with other cell types and influence the cardiovascular environment through the production of cytokines and chemokines that are angiogenic and/or inflammatory. Physical activity is known to confer positive cardiovascular benefits and decrease cardiovascular disease risk. We aim to evaluate how physical activity modulates these cells and their angiogenic and inflammatory signal communication to better understand their contribution to cardiovascular health. Populations of interest are those at risk for cardiovascular disease such as menopausal women and patients with type 2 diabetes. Results from our work may provide novel targets and strategies to reduce the overall cardiovascular disease burden.
Learn more at the Molecular and Cardiovascular Physiology Laboratory website: people.umass.edu/switkows/Laboratory_Home.html
- BS College of William and Mary, 1995
- MS University of Delaware, 2000
- PhD University of Maryland, 2008
- Postdoctoral Training University of Maryland, 2010