Mechanical properties of individual cells are determined by a specific composition and an arrangement of sub-cellular organelles. Since cells can be viewed as heterogeneous polymeric materials exhibiting strain-rate dependent mechanical properties, we are interested in cells’ nonlinear mechanical responses in high-strain-rate regimes and the development of high-strain-rate biomechanical characterization methods.
In order to apply HSR mechanical stimuli to a single cell, we are trying to employ a recently developed micro-ballistics technique that can produce a high-speed collision of a single micro-particle to a target specimen. Utilizing extreme mechanical stimuli from the microscopic collision, we are trying to differentiate any subtle difference in the intrinsic mechanical properties of individual cancer cells.
Learn more at blogs.umass.edu/leejh/
- BS Physics, Dankook University, South Korea, 1994
- MS Physics, Dankook University, South Korea, 1996
- PhD Condensed Matter Physics, Iowa State University, 2006
- Postdoctoral Associate, Ames Laboratory-USDOE, 2006-207
- Postdoctoral Associate, Materials Science & Engineering, MIT 2007-2011
- Research Scientist, Rice University, 2011-2014