The University of Massachusetts Amherst

Small Molecule Delivery & Nutraceuticals

Emrick and colleagues have developed a polymeric pro-drug that exhibits reduced drug uptake in healthy tissues and enhanced drug accumulation in tumors using BALB/c mice bearing 4T1 tumors. These pro-drugs has no apparent innate or adaptive immune system response (Mol. Pharm. 2016, 11, 1715-1720).

Understand the self-assembly of carrier molecules and utilize them to develop efficient delivery vehicles for small molecules and nutraceuticals. These molecules are non-covalently encapsulated in carriers or developed in a pro-drug format. Strategies for controlled release and targeted delivery to specific cells and tissues are being developed. Impact areas include oncology, liver diseases such as NASH, and food-based products such as nutraceuticals.

S. Thayumanavan
Leadership Team
Steering Committee
Eric Decker
Steering Committee
Todd Emrick
Steering Committee
Neil Forbes
Steering Committee
D. Julian McClements
Steering Committee
David Moorman
Steering Committee
Gregory N. Tew
Steering Committee
Contact Info

D. Julian McClements, Food Science
(413) 545-1019

Todd Emrick, Polymer Science & Engineering
(413) 577-1613