Contact
Email
Location
LSL N263
Education
Postdoc, Brain/Cognitive Aging; University of California, San Francisco  2024
PhD, Neuroscience; Pohang University of Science and Technology 2017
 
Research interests
The Park Lab is dedicated to advancing our fundamental understanding of cognitive decline associated with aging and age-related neurological conditions, with a specific focus on body-to-brain communication. Our research places a keen emphasis on exploring the roles of platelets and platelet factors in brain/cognitive aging. 
 
Publications

Park C, Hahn O, Gupta S, Moreno A, Kedir B, Wang D, Villeda S, Wyss-Coray T, Dubal D. “Platelet factors are induced by longevity factor klotho and enhance cognition in young and aging mice.” (2023) Nat Aging. 3(8): 1067–1078.

Castner S, Gupta S, Wang D, Moreno A, Park C, Chen C, Poon Y, Groen A, Greenberg K, David K, Boone D, Baxter MG, Williams GV, Dubal D. “Longevity factor klotho enhances cognition in aged nonhuman primates.” (2023) Nat Aging. 3(8):931-937. 

Suh BK, Lee SA, Park C, Suh Y, Kim SJ, Woo Y, Nhung TTM, Lee SB, Mun DJ, Goo BS, Choi HS, Kim SJ, Park SK. “Schizophrenia-associated dysbindin modulates axonal mitochondrial movement in cooperation with p150 glued.” (2021) Mol Brain. 14(1):14.

Lee DW, Lee S, Min C, Park C, Kim JM, Hwang CS, Park SK, Hwang I. “Cross-species functional conservation and possible origin of the N-terminal specificity domain of mitochondrial presequences.” (2020) Frontiers in Plant Science. 13;11:64.

 Park SJ, Lee SB, Suh Y, Kim SJ, Lee N, Hong JH, Park C, Woo Y, Ishizuka K, Kim JH, Berggren PO, Sawa A,Park SK. “DISC1 Modulates Neuronal Stress Responses by Gate-Keeping ER-Mitochondria Ca2+ Transfer through the MAM.'' (2017) Cell Rep. 5;21(10):2748-2759.

Park C, Lee SA, Hong JH, Suh Y, Park SJ, Suh BK, Woo Y, Choi J, Huh JW, Kim YM, Park SK. “Disrupted-in-schizophrenia 1 (DISC1) and Syntaphilin collaborate to modulate axonal mitochondrial anchoring." (2016) Mol Brain. 2;9(1):69. F1000 Prime Recommended.

Hong JH, Kwak Y, Woo Y, Park C, Lee SA, Lee H, Park SJ, Suh Y, Suh BK, Goo BS, Mun DJ, Sanada K, Nguyen MD, Park SK. “Regulation of the actin cytoskeleton by the Ndel1-Tara complex is critical for cell migration." (2016) Sci Rep. 22;6:31827.

Lee SA, Kim SM, Suh BK, Sun HY, Park YU, Hong JH, Park C, Nguyen MD, Nagata K, Yoo JY, Park SK. “Disrupted-in-schizophrenia 1 (DISC1) regulates dysbindin function by enhancing its stability.” (2015) J Biol Chem. 13;290(11):7087-96.

Park C, Park SK. “Molecular links between mitochondrial dysfunctions and schizophrenia." (2012) Mol Cells. 33(2):105-10.