Becky Miller
(413) 577-3804
(413) 545-3291
Molecular mechanism of muscle contraction
Background and Training

PhD: San Diego State University and UC San Diego
Postdoctoral training: University of Vermont

Research Summary

Muscle is a complex tissue that couples the energy released from biochemical reactions to mechanical movement, resulting in contraction. To facilitate this contraction (shortening) of the tissue, two proteins, myosin and actin, interact directly and repeatedly. My graduate and postdoctoral training focused on the relationship between structure and function in both myosin and actin. Primarily, I compared the biochemical properties of isolated and purified myosin isoforms or actin isoforms. Currently, I support research activities and mentor students in a laboratory investigating the effects of aging and exercise on skeletal muscle performance.