U.S. Veterinary Immune Reagent Network

Cattle

Recombinant proteins have been made for the following genes: CCL2, CCL5, CCL11, CXCL9, CXCL10, CXCL11, IFN-γ, IFN-α, IL-1β, IL-2, IL-4, IL-6, IL-8, IL-13, IL-15, IL-17, IL-23A, TNF-α
Recombinant proteins will be made for the following genes:
IFN-β, IL-5, IL-7, IL-10, IL-12p35, IL-12p40, IL-18,

Monoclonals antibodies will be made to the:

Cell Surface Molecules:

TCRγ: fusion completed September 2008; 3 mAbs,contact Dr. Cynthia Baldwin, UMass Amherst about monoclonals.

TCRδ: Ig vector protein immunized and fusion scheduled 4/2/09(UMass Amherst); re-cloned into IL-4 vector December 2009 (Cornell) with monoclonal production scheduled (UMass Amherst).

IL-10Rβ: protein produced (Cornell).

IL-23R: protein produced (Cornell).

CCR7: protein produced;several mAbs produced; screening and characterization ongoing(UMass Amherst).

Cytokines and Chemokines:

IL-13: fusion completed Decemeber 2008; mAbs lost specificity;mammlian expressed protein produced (UMass Amherst); immunizations in progress.

IFNα: protein production scheduled December 2008 (Kingfisher);mammalian expressed protein produced (UMass Amherst); immunizations in progress.

IL-17: protein production scheduled Spring 2010 (Kingfisher); mammalian expressed proteins produced(UMass Amherst); immunizations in progress.

IL-23: protein production scheduled February 2009 (Kingfisher).

IL-6: protein scheduled April 2009 (Kingfisher); mammalian expressed proteins produced (UMass Amherst); immunizations in progress.

Click here to download the survey form.
Then fill it out, and send it back to the appropriate species coordinator.

Last updated: July 2011