U.S. Veterinary Immune Reagent Network

Species pages contain targeted molecule updates and indices of commercially available reagents. The buttons below provide Network-wide information.

Progress
Primers
Bioassays
References for Genes
Posters



The buttons below provide information about available reagents from US VIRN project directors (Kingfisher Biotech, Inc) and sister European initiatives (The Immunological Toolbox).




Genes for CYTOKINE/CHEMOKINE and CELL SURFACE MOLECULES may be obtained by emailing: Catfish: Dr. Melanie Wilson; Cattle & Swine: Mr. Ted Hudgens; Chicken: Dr. Hyun Lillehoj; Trout: Dr. John Hansen


Project Description: A major obstacle to disease control in cattle, chickens, pigs, horses and fish is the lack of sufficient immunological reagents. The goal of the US-VIRN is to generate monoclonal antibodies (mAb) that identify the major leukocyte subpopulations (T and B lymphocytes, NK cells, macrophages, dendritic cells, neutrophils), antibody classes and produce bioactive recombinant cytokines and chemokines as well as antibodies to them and their receptors for these species. These reagents will be used to: (1) evaluate changes during disease and following vaccination and (2) give scientests the ability to manipulate immune system cells to ascertain their roles in protective immunity as well as in immunopathology. Development of the above reagents will address the USDA-CSREES goal of enhancing the safety of the Nation's agriculture and food supply by aiding in the development of vaccines. Products developed will benefit a large group of researchers, including veterinary clinicians, immunologists, pathologists, and microbiologists.


Project Funding
USDA-CSREES proposal 2005-01812
Peter Johnson, DVM, Ph.D. , Director
pjohnson@csrees.usda.gov
http://www.csrees.usda.gov












Last updated: July 2009.





For further information about the U.S. Veterinary Immune Reagent Network, contact Dr. Cynthia Baldwin University of Massachusetts Amherst.

For information about the US VIRN website, contact Ms. Dannielle Tompkins, University of Massachusetts Amherst.

Project Directors:

Catfish: Dr. Melanie Wilson & Dr. Eva Bengten,
University of Mississippi Medical Center

Equine: Dr. Bettina Wagner, Cornell University

Poultry: Dr. Hyun Lillehoj, USDA-ARS (Maryland

Cattle: Dr. Cynthia Baldwin, University of Massachusetts

Pig: Dr. Joan Lunney,
USDA-ARS (Maryland)

Trout: Dr. John Hansen, Western Fisheries Research Center, USG &
Dr. Erin Bromage, University of Massachusetts Dartmouth

Protein Expression: Kingfisher Biotech &
Dr. Bettina Wagner,
Cornell University


Related Sites

CIgW website

IMGT Website

GenBank

PubMed

Dutch Cytokine Group

MSU Animal Genomics

National Institute of Allergy and Infectious Diseases

Rabbit Genome Resources

The Immunological Toolbox, BBSRC

VetImm Email List