Carlos M. Gradil, DVM, MS, PhD, DACT

Extension Associate Professor

Phone: 413-577-2214
Fax: 413-545-6326
Email: cgradil@vasci.umass.edu
Classes: Equine Diseases, Parasites & Treatment; Equine Reproduction; Horse Management
Equine Reproductive Services:
http://www.umass.edu/vasci/eqreprodctr/

M.S./Ph.D.: University of Minnesota
DVM: University of Lisbon, Portugal
Postdoctoral Training:
University of Minnesota
University of Ottawa
Cornell University

Honors and other distinctions:
AID, Fulbright, NATO, Rockefeller Fellow
Phi Zeta, Kappa Chapter
Diplomate of the American College of Theriogenology

Assisted reproductive technologies :

My current research interests include determination of PLC zeta (PLCζ) concentration in sperm of dogs and equine and how it relates to fertility. Some cases of male infertility, especially those associated with normal sperm numbers and motility may be caused by decreased amounts of a factor(s) in the sperm responsible for inducing egg activation and initiation of embryo development. Less than optimal fertility may be also explained by decreased amounts of this protein in sperm. This putative factor is likely to be the recently identified PLCζ. We are securing specimens of infertile dogs and stallions that visit our services as has been recently published in: C. Gradil, S-Y. Yoon, J. Brown, C. He, P. Visconti, R. Fissore. 2006. PLCζ: a marker of fertility for stallions? Animal Reproduction Science 94:23-25.

Publications

Gradil CM, Watson RE, Renshaw RW, Gilbert RO, Dubovi EJ.1999. Detection of bovine immunodeficiency virus DNA in the blood and semen of experimentally infected bulls. Veterinary Microbiology. 70:21-31.

Gradil CM, Ball BA. 2000. The use of pentoxifylline to improve motility of cryopreserved equine spermatozoa. Theriogenology. 54 (7): 1041-1047.

Volkmann DH, Gilbert RO, Gradil C, Linke R. 2002. Leukocytes trapped in the fetal membranes of newborn foals. Theriogenology 58:787-790.

C. Gradil, S-Y. Yoon, J. Brown, C. He, P. Visconti, R. Fissore. 2006. PLCζ: a marker of fertility for stallions? Animal Reproduction Science 94:23-25.

Frederico L, Gerard M, C Pinto, C Gradil. 2006. Bilateral occurrence of granulosa-theca cell tumors in an Arabian mare. The Canadian Veterinary Journal. In Press

Pertinent Book Chapters

Gradil CM, Yeager A, Concannon P. 2000. Pregnancy Diagnosis in the Bitch. In: Kirk’s Current Veterinary Therapy, XIII edition, (J. Bonagura ed). W. B Saunders Company, Philadelphia, PA.

Gradil CM, Yeager A, Concannon P. 2006. Assessment of reproductive problems in the dog Recent Advances in Small Animal Reproduction Concannon P.W. , England G. , Verstegen J. and Linde-Forsberg C. (Eds.) In Verstegen III J. and Linde-Forsberg C. (Eds.). International Veterinary Information Service, Ithaca NY ( www.ivis.org) , Last updated: 19-Apr-2006; A1234.0406.

Gradil CM. 2006. Subinvolution of placental sites. Veterinary Clinical Advisor. In Press.

CM Gradil. 2006. Chapter 215: Semen analysis; Blackwell’s Five-Minute Veterinary Consult: Diagnostic Procedures and Laboratory Tests. Shelly Vaden, Joyce Knoll, Larry P. Tilley and Frank WK Smith, Jr (Eds). In Press.

CM Gradil. 2006. Chapter 216: Semen Collection; Blackwell’s Five-Minute Veterinary Consult: Diagnostic Procedures and Laboratory Tests. Shelly Vaden, Joyce Knoll, Larry P. Tilley and Frank WK Smith, Jr (Eds). In Press.

CM Gradil. 2006. Chapter 217: Semen Preservation. Blackwell’s Five-Minute Veterinary Consult: Diagnostic Procedures and Laboratory Tests. Shelly Vaden, Joyce Knoll, Larry P. Tilley and Frank WK Smith, Jr (Eds). In Press.

Other activities:

Founder in 1996 and present co-owner of < cafereprod-L@cornell.edu > a mailing list in small animal reproduction. The list is subscribed by over 250 leading names in the field worldwide facilitating access to expert opinion and contacts to veterinary colleges and reproduction specialty practices around the world.