University of Massachusetts Amherst

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biomedical

Pioneer Valley Life Sciences Institute

PVLSI is a UMass Amherst-Baystate Medical Center collaboration. Biomedical research at PVLSI is dedicated to improving human health by developing creative new approaches for the diagnosis and treatment of disease. By coupling the unique resources of a major research university with one of the largest teaching hospitals in New England, we continue to create interactive teams of allied health professionals, life scientists and physical scientists to focus on clinical disorders and technologies.

Department(s): 

Biology
Shared Resource

College/Unit: 

College of Engineering

Contact: 

Steven D. Goodwin

Resources: 

17000 square feet of newly renovated research space complete with surgical suites animal facilities and bench space for more than fifty researchers.<br>Core facilities for animal care histology and cell culture. Other specialized equipment includes: FACScan confocal laser microscope real time PCR and robotic devices for conventional histology and immunohistochemistry.

Availability: 

Public

Research: 

Muscle Biology and Imaging Laboratory

The mission of the laboratory is to unravel the complex mechanisms of human skeletal muscle function. To accomplish this, we study the muscle's response to an environmental challenge, such as overexertion, disuse, and training. Our studies currently focus on understanding the underpinnings of muscle damage, atrophy, and hypertrophy and their functional outcomes.

Department(s): 

Kinesiology

College/Unit: 

Public Health and Health Sciences

Contact: 

Priscilla Clarkson

Resources: 

Spot insight QE camera, EclipseNET 1.16, EC135-90 power supply, IEC MicroMax RF refrigerated centrifuge, Sorvall Legend RT refrigerated centrifuge, Ultrasonic cell disruptor, Ultra Turrax homogenizer, OWL electrophoretic separation systems for agarose and Polyacrylamide gels, VWR RNA Workstation, Fotodyne Image analysis system (UV and white light)

Availability: 

Private

Research: 

Intelligent Modeling, Analysis and Design (I-MAD) Laboratory

The I-MAD Laboratory seeks new methods and technologies for significantly improving how organizations can effectively manage, reuse, interoperate, and adapt EAMs in the context of their product development activities.

Department(s): 

Mechanical and Industrial Engineering

College/Unit: 

College of Engineering

Contact: 

Ian Grosse

Resources: 

engineering analysis modeling system (ON-TEAM: a Java-based ontological framework) to support product design.

Availability: 

Private

Research: 

Genomics Resource Laboratory

Lab offers a range of analytical services, including: genotyping platforms (microsatellite and SNP analyses); an E-GENE capillary sequencing for size separation of unlabelled PCR products to 2-bp resolution; and gel electrophoresis for SSCP, DGGE, TGGE, and related native and denaturing electrophoresis protocols. Researchers from UMass Amherst, the Five Colleges Consortium and the greater Pioneer Valley scientific community, and beyond are invited to inquire about how to access these services.

Department(s): 

Biology
Shared Resource

College/Unit: 

Natural Sciences and Mathematics
Vice Provost for Research

Contact: 

Stephen Rich

Location: 

B2 Fernald Hall

Resources: 

Two liquid-handling robots and specialized software (EMBOSS, Sequencher; Staden package; Bioedit; FinchTV; MxPro for Stratagene; Totallab analysis for gel image).

Availability: 

Public

Research: 

Computational Biology Laboratory

The UMass Amherst Computational Biology Lab in the Department of Computer Science is concerned with computational and modeling problems behind many of the major questions in molecular biology and genetics. Our bioinformatics research involves the use of machine learning, modeling, and optimization techniques for DNA and protein sequence analysis.

Department(s): 

Computer Science
Shared Resource

College/Unit: 

Natural Sciences and Mathematics

Contact: 

David Kulp, Oliver Brock

Location: 

Computer Science Building

Availability: 

Public

Research: 

Biostatistics Consulting Center

The BCCUMA can support all areas of research, from initial proposal development and study design through statistical analysis and reports.Design for data collection instruments supported include paper questionnaires, scannable forms, computerassisted telephone interviews (CATI), or web-based surveys. The BCCUMA also provides data collection and data entry services.

Department(s): 

Public Health
Shared Resource

College/Unit: 

Public Health and Health Sciences

Contact: 

Elaine Puleo, Penelope Pekow

Availability: 

Private

Research: 

Assistive Technology Laboratory

AT Lab is committed to provide engineering solutions to assist people with various disabilities. The Lab combines the expertise of a faculty group strong in mechatronics, materials and testing, human factors, design theory and adaptive learning.

Department(s): 

Mechanical and Industrial Engineering

College/Unit: 

College of Engineering

Contact: 

Donald Fisher, Sunder Krishnamurty

Availability: 

Private

Research: