J. Richard Pilsner
B.A., Hamline University, 1995; M.P.H., Columbia University, 2003; Ph.D., Columbia University, 2007; Robert Wood Johnson Health and Society Scholar, University of Michigan, 2007-10
Environmental Epigenetics, Toxicology, Nutrition, DNA Methylation, Molecular Epidemiology
J. Richard Pilsner is a molecular epidemiologist committed to investigating how environmental and nutritional factors influence health outcomes via epigenetic processes. Epigenetic plays an important role in the functionality of DNA by controlling how genes are expressed. Dr. Pilsner’s environmental epigenetic laboratory has state-of-the-art equipment for high-throughput DNA methylation analyses tailored to population-based research.
Pilsner JR, Hall MN, Liu X, Ilievski V, Slavkovich V, Levy D, Factor-Litvak P, Yunus M, Rahman M, Graziano JH, Gamble MV. Influence of prenatal arsenic exposure and newborn sex on global methylation of cord blood DNA. PLoS One. 2012 7(5):e37147.
Pilsner JR, Liu X, Ahsan H, Ilievski V, Slavkovich V, Levy D, Factor-Litvak P, Graziano JH, Gamble MV. Genomic methylation of peripheral blood leukocyte DNA: influences of arsenic and folate in Bangladeshi adults. Am J Clin Nutr. 2007 Oct;86(4):1179-86.
Pilsner JR, Hu H, Ettinger A, Sánchez BN, Wright RO, Cantonwine D, Lazarus A, Lamadrid-Figueroa H, Mercado-García A, Téllez-Rojo MM, Hernández-Avila M. 2009. Influence of Prenatal Lead Exposure on Genomic Methylation of Cord Blood DNA. Environ Health Perspect: 2009 Sept: 117(9): 1466-71.
Pilsner JR, Hu H, Ettinger A, Sánchez BN, Wright RO, Cantonwine D, Lazarus A, Lamadrid-Figueroa H, Mercado-García A, Téllez-Rojo MM, Hernández-Avila M. Maternal MTHFR Genotype and Haplotype Predict Deficits in Early Cognitive Development in a Lead-exposed Birth Cohort in Mexico City. Am J Clin Nutr. 2010 Jul;92(1):226-34.
Pilsner JR, Liu X, Ahsan H, Ilievski V, Slavkovich V, Levy D, Factor-Litvak P, Graziano JH, Gamble MV. Folate Deficiency, Hyperhomocysteinemia, Low Urinary Creatinine and Hypomethylation of Leukocyte DNA are Risk Factors for Arsenic-Induced Skin Lesions Environ Health Perspect: 2009 Feb; 117(2):254-60.