Simons Investigators in Mathematical Modeling of Living Systems

Simons Investigators in Mathematical Modeling of Living Systems (MMLS) is a joint program of the Mathematics and Physical Sciences and Life Sciences divisions of the Simons Foundation. Investigators in MMLS are outstanding scientists, often with mathematics or theoretical physics backgrounds, now engaged in research based on mathematical modeling in the life sciences.

A broad spectrum of research areas within the life sciences will be considered, ranging from cellular-level issues of organization, regulation, signaling, and morphogenic dynamics to the properties of organisms and ecology, as well as neuroscience and evolution; however, preference will be given to areas in which modeling approaches are less established and, for this reason, bioinformatics- and genomics-related proposals fall outside the scope of the program. In all cases, preference will be given to work that relates closely to experiment, developing mathematical models that can explain data, suggest new classes of experiments and introduce important new concepts.

  • Eligibility: at the time of appointment (August 1, 2018), Investigators should be in the early stages of an academic career (within 8 years of the start of first faculty position) and have a primary appointment as a faculty member. Their primary department affiliation must have a PhD program.
  • Award Amount: $660,000 over 5 years ($100,000/year in research support for Investigator; $10,000/year for the Investigator's department; $22,000/year in overhead) 
  • Number of Awards: 7
  • Number of UMass Amherst Nominees: up to 2 

Internal Application Process

The internal selection process will be led by a committee composed of the deans of internal applicants' respective schools and colleges or their designees and, if necessary, the Provost, Vice Chancellor for Research Engagement, or faculty with relevant expertise and informed by the grant programs' guidelines and submission requirements.

If you are interested in applying to either of these programs please email a pre-proposal with the following items, in the order listed, in a single PDF by September 16, 2017 to

  • A research statement outlining your research vision and plans (two-page limit; references and figures do not need to be included in the page limit but should not exceed an additional page).
  • Curriculum vitae, including Ph.D. year, institution, advisor, postdoctoral institutions and advisors, positions held subsequent to award of doctorate, and up-to-date publication list. 
  • A list of postdoctoral fellows and Ph.D. students previously and currently supervised.
  • List of current and pending grant awards.

For additional information, visit the programs' website.  To view the typical profile of successful nominees, applicants are encouraged to visit Current Awardees.  If you have technical questions about the grant program(s) or your eligibility, please contact Liz Smith in Corporate and Foundation Relations.